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Dan Chen Profile
Dan Chen

@DanChenMDPhD

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Co-author of the cancer-immunity cycle and the immune set point with Ira Mellman; Opinions are my own.

Joined August 2014
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@DanChenMDPhD
Dan Chen
2 months
RT @JohnCendpts: We all know it's tough out there in @biotech land. Down rounds, IPO window shut, Trumpster fires, all of that. But the sta….
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@DanChenMDPhD
Dan Chen
11 months
RT @BertrandBio: discussant slides on $SMMT #Akeso ivonescimab / $BNTX #Biotheus BNT327 - PM8002 in TNBC, ESG401 TROP2 ADC in HR+/HER2- & T….
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@DanChenMDPhD
Dan Chen
11 months
RT @JonathanWosen: Genentech, a biotech with a storied past, confronts new turbulence in the present. My story for @statnews, based on inte….
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statnews.com
Genentech is a biotech company with a storied past. But what will happen in its future?
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@DanChenMDPhD
Dan Chen
11 months
RT @SethAbramson: Utterly brutal. Deserves 300,000 retweets.
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@DanChenMDPhD
Dan Chen
1 year
Amazing to have Jesse B. Owens, Jennifer Manning, Omid Harandi, Jay Wohlgemuth, Ray Tabibiazar, +++ as partners and founders making this happen!
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linkedin.com
KOMO Biosciences | 1,274 followers on LinkedIn. Next-Generation Targeted Gene Integration Technology | KOMO Biosciences is a next-generation targeted gene integration technology company driven by the...
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@DanChenMDPhD
Dan Chen
1 year
KOMO BIOSCIENCES- #gene #modification, from the dish, accelerating biologic therapy development and manufacturing, to patients. It's exactly the broad #technology and #engineering that Genesis seeks to create, incubate and help grow into companies that benefit human health.
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@DanChenMDPhD
Dan Chen
1 year
Super excited and happy to launch KOMO BIOSCIENCES, the first Genesis BioCapital company and technology! Komo is set to deliver transformative advances in #gene modification.
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endpoints.news
Scientists at the University of Hawaii have improved tools for making large changes to genomes and have licensed the technology to a new startup called Komo Biosciences, its leaders told ...
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@DanChenMDPhD
Dan Chen
1 year
RT @tompowles1: Neoadjuvant chemo/nivo with adjuvant nivo show ⬆️ DFS (HR 0.58) & ⬆️pCR in NSCLC. 23% & 35% didn’t have surgery/adjuvant n….
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@DanChenMDPhD
Dan Chen
1 year
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@DanChenMDPhD
Dan Chen
1 year
γ, flex in clustered plasma membrane protein distance; ο, orientation between two clustered plasma membrane proteins; δ, distance between two cells, plasma membranes, or surfaces; and x, y, z, dimensions of excluded proteins of interest.
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@DanChenMDPhD
Dan Chen
1 year
biophysical relationships that can be described in terms of RBVs as follows: α, distance between two clustered plasma membrane proteins; β, distance between two clusters; n, number of clustered plasma membrane proteins in a cluster; N, number of clusters;.
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@DanChenMDPhD
Dan Chen
1 year
Advances here will not only lead to more powerful therapeutics, it will usher in Directed Design and help us keep our human understanding up with #ai driven findings. Immunity as biophysics at the surface of a T cell.
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@DanChenMDPhD
Dan Chen
1 year
One of the important gaps in our understanding of biology comes from thinking of interactions as 2D diagrams rather than a series of biophysical interactions that occur, for instance, at the cell surface. # cancer #immunity #Immunotherapy #biophysics.
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@DanChenMDPhD
Dan Chen
1 year
a tour de force of a manuscript!.
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@DanChenMDPhD
Dan Chen
1 year
Like Judo- using cancer against itself!.
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@DanChenMDPhD
Dan Chen
1 year
Such an important discovery published by the @KoleRoybal and @jaehyukchoimd labs relating to specific mutations that can drive non-physiologic T cell functional states. Implications for both our understanding of T cell biology and #cancer #immunotherapy approaches.
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@DanChenMDPhD
Dan Chen
2 years
Awesome post! LOL!.
@getnickwright
nick wright
2 years
I know it looks grim right now, but I’m sure Niners fans/media feel fine because of their MVP candidate/unfairly maligned/Joe Montana 2.0 at QB.
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@DanChenMDPhD
Dan Chen
2 years
Continued support for the importance of PDL1 pathway inhibition combined with VEGF blockade. An interesting Venn diagram for non-overlapping but related biology between #cancer #immunotherapy and #angiogenesis. Positive trials now in #NSCLC #HCC #RCC #ProstateCancer #endometrial.
@nataliagandur
Dra. María Natalia Gandur Quiroga
2 years
💫🌟Fantastic talk with the usual clarity!!!👏👏👏.🔬 🔝🔝🔝#CONTACT-2 Phase 3 Study Results are in! Combining cabozantinib & atezolizumab shows promise for mCRPC. By @neerajaiims .🎯 Highlights:.mCRPC with prior NHT failure, extrapelvic nodal or visceral metastasis. 📊 Key
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@DanChenMDPhD
Dan Chen
2 years
RT @ImmunityCP: As we get ready for 2024, let's look back at the Immunity covers of 2023! Thank you to everyone that contributed to the sci….
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@DanChenMDPhD
Dan Chen
2 years
RT @bradloncar: Think this is the most interesting office I’ve visited in Silicon Valley. Love the board in the background with the names o….
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