TheTaylorLab
@DTaylorLab
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Research lab at Case Western Reserve University using structural biology, molecular mechanism, and cellular outcome to understand and treat cancer.
Cleveland, OH
Joined June 2020
🌟 Exciting News! Eric has been named #PostdocOfTheMonth! 🎉 Check out the full interview on the university's daily news site! #ScienceSpotlight [Link to interview] 📚🔬.
thedaily.case.edu
During his first week as an undergraduate student at Case Western Reserve University, Eric Mosher made a pivotal decision: he joined a lab. That experience laid the groundwork for a four-year...
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RT @KeisukeMotone: Our preprint is out! We hacked the @nanopore sequencer to read amino acids and PTMs along protein strands. This opens up….
biorxiv.org
The ability to sequence single protein molecules in their native, full-length form would enable a more comprehensive understanding of proteomic diversity. Current technologies, however, are limited...
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RT @GoogleDeepMind: Today in partnership with @IsomorphicLabs, we're sharing progress on the next generation of #AlphaFold. 🧬. Our new mode….
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🦠🧬 Dive into the fascinating world of how bacteriophage T4 ingeniously hijacks E. coli's cellular machinery! Unveil the intriguing process of ‘RNAylation’! RNAylation-installing RNA strands onto the arginine residues of target proteins. #RNAylation.👇.
nature.com
Nature - Bacteriophage T4 uses an enzyme known as ADP-ribosyltransferase ModB to modify the translational apparatus of bacteria it infects, not only by ADP-ribosylating proteins, but also by...
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🎉 Kudos to @vignesh_k757 and Cech team for revealing a stunning structure & applying streptavidin grids innovatively! Shedding light on the fascinating functional role of G4 RNA, pushing the boundaries of our understanding. Fantastic achievement! .
science.org
Cryo–electron microscopy structure of RNA-bound PRC2 dimer elucidates an unexpected mechanism of PRC2 inhibition by RNA.
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🎉 Huge congrats to Brendan Sheehan for securing a training grant from the National Institute of General Medical Sciences! 🎓 So proud of this remarkable achievement. Onward and upward! 🌟 #NIGMS #T32 #FutureOfScience #GrantAchievement 🙌🔬.
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RT @gouthamnarla: So proud of our research team and our collaborators; our paper just came out in Nature Communications today.So proud of o….
nature.com
Nature Communications - Loss of PP2A activity is often associated with cancer but the underlying mechanism remains unclear. Here, the authors show that decreased methylation of PP2A catalytic C...
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RT @gpsapkota: PP2A holoenzyme is thought to dephosphorylate hundreds of substrates. By degrading its catalytic subunit followed by an unbi….
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Ever wonder about the hidden costs of drug toxicity? The latest research sheds light on an often overlooked area: the impact of off-target drug interactions on intracellular RNAs. 🧬.#DrugSafety #Transcriptomics #Pharmacology #Toxicity #Innovation.
nature.com
Nature Chemistry - Now a reactivity-based RNA profiling strategy can measure the global off-target transcriptome interactions of small-molecule drugs at single-nucleotide resolution. Using this...
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RT @Zhanyinpeng: Very nice to read, the needs of map the interactions of small-molecule drugs with RNA in cells 🤔🤔🤔.
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🎉 Exciting News! 🎉 A huge congratulations to #twitterless Eric Mosher for securing a Cancer Biology Training Grant from the prestigious @caseccc and @theNCI! Here's to groundbreaking research ahead! 🧪🔬 #CancerResearch #TrainingGrant #TeamExcellence.
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RT @thermosciEMSpec: In honor of @joachimfrank's birthday, the #cryoEM community has convened today to celebrate his contributions to scien….
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RT @Hashemyaser4: Dear #Ribosome and #CryoEM aficionados, join us for a unique opportunity to attend a symposium organized in honor of the….
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RT @SchreiberStuart: NIBR (@NovartisScience) NLRP3 inflammasome inhibitor functions as an intramolecular glue – locking the protein in an i….
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We are big fans of Cathy Hannes @HelloCancerFri1. Cathy is a cancer survivor, blogger, and one of the most positive people we've met. She is a true inspiration!.
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RT @RuthKeri2: It’s official! Bryan Webb is now Dr. Bryan Webb! Great work in CDK7 in #breastcancer and now on to finishing #medschool. P….
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Congratulations to Dr. Tawna Mangosh for the successful defense of her Ph.D. thesis!.
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