The Cosa Group
@CosaGroup
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We develop fluorescence methods to study dynamic systems from the single molecule to the cellular level at McGill.
Montréal, Québec
Joined February 2018
Take advantage of your @photoIUPAC2024 inscription and get two free tickets to visit the local museums of the city, thanks to @AjuntamentVLC Check the listed museums⬇️⬇️
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Our latest paper was selected to appear in the PNAS Showcase on Kudos! Check it out here: https://t.co/eX4AkldnyH
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Lipid-derived electrophiles are more than just biomarkers of #ferroptosis. Check out our latest, out now in PNAS: https://t.co/Z7bAGiwzNJ
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Welcome Undergraduates (Cohort 5)! Looking forward to you joining the PROMOTE team this May 2024. @NSERC_CRSNG @SleimanHanadi @F_ANAtico @mmckeague @Yingfu8888 @WildsLab @MollyShoichet @nic_moitessier @CosaGroup
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Our talented Paty Garcia and the McGill Chemistry Outreach Team @McGillChemOut inspiring young girls to see themselves as scientists! So proud of you and the team! @CosaGroup @mcgillu @realventures @McGillChemistry
https://t.co/KxgvsFwneu
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Congratulations to Dr. Zhang who successfully defended his PhD last week!
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Learn about Photostabilizing Strategies for Single-Molecule Fluorescence Microscopy (Lab training module) https://t.co/nIH3Q6cVqF
@CosaGroup, @NSERC_CRSNG
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Congratulations to Dr. Van Kessel who successfully defended his PhD in November!
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Interested in efficient strategies to build nanostructures? Check out our latest pre-print where Paty and @casey_platnich detail their automated synthesis of DNA nanotubes!
biorxiv.org
DNA nanotechnology has revolutionized our ability to position matter at the nanoscale, but the preparation of DNA-based architectures remains laborious. To facilitate the formation of custom struct...
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Curious as to how photodynamic therapy works in bacteria at the single-cell level? Check out our latest paper in @J_A_C_S
pubs.acs.org
Innovative therapeutic approaches are required to battle the rise of antibiotic-resistant bacterial strains. Tapping on reactive oxygen species (ROS) generation in bacteria induced by bactericidal...
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Thanks to @CRBSMcGill for again organizing a fantastic symposium this year. A series of great speakers, including Heidi from the Cosa group!
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Congratulations to Dr. McCain who successfully defended her PhD last month!
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What happens in a cell after lipid hydroperoxide accumulation during ferroptosis? Our latest work brings us closer to an answer. Check it out as a pre-print!
MRP1 inhibition by lipid-derived electrophiles during ferroptosis illustrates a role for protein alkylation in ferroptotic cell death https://t.co/oqYsNttiY5
#bioRxiv
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You saw it as a pre-print, but now it's even better! Check our latest advance in the photoprotection of cyanine dyes.
Superior Photoprotection of Cyanine Dyes with Thio-imidazole Amino Acids | Journal of the American Chemical Society @mcgillu
@McGillChemistry #Photoprotection #CyanineDye #Thioimidazole #AminoAcid
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Congratulations to Dr. Sakaya who successfully defended her PhD last week!
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Wondering how viral polymerases work? Our latest paper uses single-molecule fluorescence studies to investigate HCV polymerase. Check it out @ACS_Infectious
https://t.co/2L6WK9cKlQ
@YasserGidi @LovellTerri
pubs.acs.org
The hepatitis C virus (HCV) nonstructural protein 5B (NS5B) polymerase catalyzes the replication of the (+) single-stranded RNA genome of HCV. In vitro studies have shown that replication can be...
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What a fantastic week it was! Great science and great people.
Clearly, there never was a better time to work on ferroptosis! 10+ yrs after its discovery, #ferroptosis has entered its next phase! Thrilled about the numerous young scientists presenting their groundbreaking work! Stay tuned… @Ferroptosis2306 @Ferroptosis1
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Meet the research leaders that have organized this inaugural Science Research Conference that will allow probe developers and users to come together. #OPCSRC @CosaGroup @Amandeepk28 @lizjnew @SchnermannLab Register Now - Early registration closes 4/23: https://t.co/n4XyHd8k2e
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Frustrated by fluorophores photobleaching? Check out our latest preprint: "Superior Photoprotection of Cyanine Dyes with Thio-imidazole Amino Acids" @ChemRxiv
https://t.co/CMu6DjKqrV
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Curious how lipid membranes behave during oxidation? Check out our latest @ACS_Langmuir:
pubs.acs.org
The physical properties of lipid membranes depend on their lipid composition. Photosensitized singlet oxygen (1O2) provides a handle to spatiotemporally control the generation of lipid hydroperoxides...
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