Cortés Lab
@CortesLab
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We study DNA topology, the action of topoisomerses and DNA break repair to understand genome organization, dynamics and stability @CNIO
CNIO (Madrid, Spain)
Joined December 2019
🔥🔥🔥 PREPRINT 🔥🔥🔥. Wanna know how your favorite gene affects double-strand break repair outcome/CRISPR-Cas9 gene editing?. Check this out! ⬇️ #REPAIRome.
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RT @GMillanZambrano: Have a look at our review in @MolecularCell . We explore how histone modifications serve as integrators of genome acti….
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RT @JCReyes_lab: En nuestro grupo en @cabimer investigamos sobre el síndrome por deficiencia en el gen CHD8. Buscamos a personas diagnostic….
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RT @rfleiro: Many thanks to @FundlaCaixa @CaixaResearch for the incredible support to work on this important problem together with Borja Ib….
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Very excited with the opportunity to take our basic discoveries on DNA topology and topoisomerase function to possible applications in our fight against cancer with this #CaixaResearch grant. Thanks @CaixaResearch!. Opportunities to join this project @CNIOStopCancer will follow.
🧬 Debido a su rápido crecimiento, las células tumorales son más propensas a acumular nudos y enredos en su ADN. Con una ayuda #CaixaResearch, @CortesLab estudiará cómo pueden estos errores usarse para desarrollar nuevas herramientas de diagnóstico y tratamiento del cáncer.💊
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RT @CNIOStopCancer: @CaixaResearch @CortesLab @Gsabiolab @rfleiro @LlorcaLab En este hilo de @caixaresearch puedes ver cómo fue la ceremoni….
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Very excited with this project in collaboration with @rfleiro, and grateful to @CaixaResearch for the support in this amazing program #CaixaImpulse.
Felipe Cortés, chief of the Topology and DNA breaks Group #CNIOStopCancer @corteslab, recieves funding from #Caixaimpulse2024 for a project aimed at a rapid autodiagnostic test based on CRISPR-Cass.✂.
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Gracias a @CaixaResearch por el apoyo! Junto con @rfleiro intentaremos llevar el potencial diagnóstico de los sistemas CRISPR-Cas al siguiente nivel, suministrando información genética directamente al paciente y acelerando la toma de decisiones clínicas @CNIOStopCancer.
🧬 El sistema CRISPR-Cas tiene un gran potencial diagnóstico, pero necesita muestras con⬆️cantidades de material genético para funcionar. Con apoyo de #CaixaImpulse Innovación, Felipe Cortés validará un método que optimiza CRISPR-Cas para su uso en autodiagnósticos rápidos. 🔗
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RT @chromodyst: An exciting meeting with lots of exciting results and interesting discussions. Thanks everyone for such a great time! https….
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Transcriptional deregulation at the basis of multiple sclerosis!. We feel privileged for the opportunity to add our small contribution to this impressive piece work. A pleasure to collaborate with such great scientists.
Very excited to share our new manuscript reporting a novel mechanism in the progression of Multiple Sclerosis (MS): dysfunction of C-terminal TAF1.Great collaborative effort with @GoCasteloBranco @CortesLab @MatuteC_ @claudio_toma_ @DrDiegoClementelabs 1/9.
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RT @LauberthLab: A new paper from @Lauberthlab by @BholaMannan and Kouki Abe shows how RNA and TOP1 work together to regulate DNA topologic….
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RT @KarstenRippe: 1/ 🤔 Do #chromatinlooping-mediated promoter-#enhancer interactions drive gene expression? Or is the local enrichment of t….
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RT @CMAzzalinLab: 📣New opportunity for #Postdoc researcher!📣.If you are interested in #telomeres and #genomestability, don’t miss this chan….
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@ErnestoLDA1811 @iscorbacho @DanielGLL_ @ChromDyn @rfleiro @gjmacintyre @CNIOStopCancer Thanks Fernando! Still polishing the web tool. Hope to be able to release it soon ….
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RT @LabBermejo: 📢 We are on the lookout 👀 for a PhD candidate! Fully funded 4-year project focused on the molecular dynamics of replication….
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4. The SAGA complex is involved in MMEJ.5. The ID11 cancer mutational signature is caused by insertional NHEJ and linked to VHL loss, hypoxia and renal cancer. And yet many uncharacterized factors/pathways in the list …. Looking forward to the feedback!. Cheers!.
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