Carlos Collet MD PhD
@ColletCarlos
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Interventional Cardiologist. Physician-Scientist. Director of Cardiovascular Imaging, Physiology and Translational Therapeutics at CRF
New York, NY
Joined June 2013
Full house at @crfheart today for a fantastic session with Prof. Stewart Pocock, Chief of Statistics. How to get to primary endpoint hierarchy right? His perspective in how to turn numbers into knowledge that changes practice. #Cardiology #ClinicalTrials #Biostatistics
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This is the perfect case to randomize in a vulnerable plaque study. Looking forward to the results!
Recta final para la inclusion del @VulnerableTrial con el paciente 500 del RCT aleatorizado. Ya quedan 100 para llegar a los 600 objetivo. Esta vez nos ha tocado en Bellvitge. Caso muy claro de una CF con ALM 2,5 mm2, carga placa 80%, arco lipido >300^ y capa fibrosa de 50 micras
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We are thrilled to pioneer the introduction of PPG into U.S. practice, an objective measure of longitudinal pressure loss that refines CAD phenotyping and predicts post-PCI physiology and clinical outcomes. Our recent @JACCJournals Advances State-of-the-Art summarizes the
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Enter a new era of interventional cardiovascular innovation! π We are proud to announce the inaugural TCT Plus Africa, coming to Tunis, Tunisia, in January 2027. ππ Mark your calendar and prepare to embark on a journey of discovery and transformation with global experts from
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Dr @ColletCarlos is speaking at at #ACIC βCan we reliably predict plaque rupture before it happens?β Join over 500 participants and a global expert faculty Register: https://t.co/DpTDJNK5Wv
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Will #CTA become the standard for assessing patients after Left Main PCI? https://t.co/iE4rOuZNbD Our editorial in @JACCJournals @crfheart @ziadalinyc @SCAI
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It's the final day of #TCT2025! Watch Ajay Kirtane and @ColletCarlos wrap up the late-breaking science to come out on Day 4. https://t.co/1OrWVeM2NM
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In patients with de novo coronary artery disease, #DCB angioplasty with rescue stenting was assoc with a higher rate of Device-oriented Composite Endpoint compared to intended DES implantation regarding DoCE at 3 yrs https://t.co/FfAQg6isuO
#TCT2025 #JACC #cvCAD @DFCapodanno
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Congratulations @g_giustinoMD ππππ
π Congratulations to Gennaro Giustino, MD (@g_giustinoMD) for receiving the Thomas J. Linnemeier Spirit of #InterventionalCardiology Young Investigator Award at #TCT2025! πYour work is shaping the future of cardiovascular care. π A huge shoutout to all the incredible
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π₯Just published with β¦@TCTConferenceβ© Impact of PPG on Clinical Outcomes after PCI β¦@American_Heartβ© Patients with low PPG had x2 the risk of adverse events β¦@crfheartβ© β¦@PCRonlineβ© β¦@JACCJournalsβ© β¦@SCAIβ©
ahajournals.org
BACKGROUND: Impaired flow following percutaneous coronary intervention (PCI) is a known predictor of adverse outcomes. The pullback pressure gradient (PPG) is a novel physiological metric that...
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AI generated histology derived from OCT Fascinating images #TCT2025 Learning pathology through OCT! @ziadalinyc @GreggWStone @crfheart @JEscaned @PCRonline
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Just published Thanks and congratulations to all the co-authors @JEscaned @ziadalinyc @divaka_perera @AntonioMariaLe2 @sbrugaletta @PCRonline @crfheart @CircAHA @BernardBruyne @fredericbouisse @DamienCollison
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π§© Why does this matter? βDiffuse disease β lower PPG β more stents, smaller lumens, more calcium β higher risk of stent failure and MI. β
Focal disease β higher PPG β lipid lesion -> better PCI results and almost NO events. This is where physiology changes role β No
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β‘οΈ Does this predicted physiology correlate with 1-year outcomes? π©855 patients (890 vessels) from the multicenter PPG Global registry β²οΈ1-year follow-up πPrimary endpoint: Target Vessel Failure (TVF) = cardiac death, MI, or ischemia-driven revascularization πVessels
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π Using a simple equation with PPG, we estimated what the post-PCI FFR would be before doing the procedure. π©Ί How well does the prediction work? Strong agreement between predicted and measured post-PCI FFR (ΞFFR r = 0.92!)
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π₯ Physiology has evolved. From a diagnostic method to a prognostic tool. π‘ What if we could predict outcomes before we stent? The Pullback Pressure Gradient (PPG)βa metric describing how disease is distributed along the coronary arteryβmay hold that key. Our latest study,
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Great to see @CardioAalst @CoreAalst ranked #3rd from OUS institutions at #TCT2025 πͺπ»πͺπ»πͺπ» @BernardBruyne @EricWyffels @jeroensonck @BarbatoEmmanue1
The SET-10 Power List is here! π
See which international institutions are recognized for their contributions to #TCT2025 β transforming heart care and driving research forward. ππ Congratulations to the #SET10 institutions for leading the charge in #CardioResearch!
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Kicking off #TCT2025 on Saturday morning, we will present the 1 year clinical outcomes of patients treated with PCI in Focal vs Diffuse disease #PPG Physiology will become more clinically relevant than ever before πͺπ»
π¨ #TCT2025 Late-Breaker alert! Dr. @ColletCarlos will share how Pullback Pressure Gradient (PPG) impacts clinical outcomes one-year after #PCI. PPG is a predictive tool that quantifies focal coronary disease to enable precise PCI decision-making for better patient outcomes.ΒΉβ»Β³
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π Ready to learn CT to guide PCI? #TCT2025, is the place to be. Donβt miss the CT-Guided PCI sessions ππ Iβll be presenting, for the first time, onπ Sunday, October 26 β 10:00 AM, data on how calcium density from CCTA impacts stent expansion β this will redefine calcium
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