CellSig_Lab
@CellsigL
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CellSig is led by Bart Vanhaesebroeck. We aim to improve understanding & drug targeting of the PI3K/PTEN pathway in cancer & beyond. #PI3Kδ #PI3Kactivators
UCL Cancer Institute, London
Joined October 2019
Dear Klaus – thank you very much for your very kind message: you & your CellSig Colleagues made these PI3K discoveries possible, and continue to do so - we now only need more approved PI3K drugs, inhibitors or activators😊. Keep up the good work !
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Congratulations to Sara Al-Jarrah Setó (‘Sarita’- in white T-shirt in front of picture) for successfully defending her PhD thesis in the @Cellsig Lab at @uclcancer, funded by PIPgen MSCA-ITN EU - https://t.co/NGpUO2F8Ap Wishing everyone a joyful and relaxing summer !!
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Great to see York Posor’s work on PI3K-C2alpha published: https://t.co/UBc5xukIjf, concluding 25 years of research in @CellsigL, dedicated to elucidating the roles of @PI3K family members by gene targeting. Many thanks to @SarahConduit & @BBSRC @EMBO @MSCActions @CRUKresearch
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Are you interested in the underlying molecular mechanisms of life? Explore the latest completed issue of the Biochemical Journal which delves into the newest developments in this exciting area! https://t.co/uG6VJgLKn1
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Great to see this published and thanks to all 42 co-authors! Including @SilaUltanir @jansen_ac @palneurolab @UKTSA @CellsigL
🚀Check out this recent publication from the mTOR Pathway Diseases node - Challenges and opportunities from bench to bedside and the mTOR node https://t.co/K3diRJ1oS5
@BatemanLab @CharlotteRTye
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The dress that visualizes the different cellular markers of an ADPS patient and a healthy person https://t.co/4R1qFiNEC5
@MSCActions #PIPgeneratingART
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Join the team at UCL and @CRUKCOLcentre 🚀Research Fellow – Computational Scientist for Proteomics. £43,124–£51,610, Full time. Closing Date 28-Feb-2025 ➡️ Informal enquiries to @Supersurinova
https://t.co/ZzIsl3roeF
ucl.ac.uk
UCL is consistently ranked as one of the top ten universities in the world (QS World University Rankings 2010-2022) and is No.2 in the UK for research power (Research Excellence Framework 2021).
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Explore our themed collection, Cell Signaling in the 21st Century. This collection captures new developments in cell signaling through research, review articles and perspective pieces. https://t.co/t0TdfBn6Zy
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Inavo improves OS - great news for patients. This is the first PI3Ki to improve OS in ER+ MBC. The future is triplets imo - eventually we will have firstline CDK4/6i + PI3K/AKTi + AI. @PIK3CApathbreak @mbcalliance
https://t.co/bkIeNHBI9V
roche.com
Updated overall survival (OS) results - a key secondary endpoint - reinforce the significant benefit of the ItovebiTM (inavolisib)-based regimen for patients with advanced PIK3CA-mutated, HR-positi...
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Explore our themed collection, Cell Signaling in the 21st Century. This collection captures new developments in cell signaling through research, review articles and perspective pieces. https://t.co/t0TdfBn6Zy
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Interested in submitting your work to an independent society publisher? Our journals cover the breadth of the molecular biosciences. With open access options available, take a look at our journals and find the home for your work: https://t.co/4ttqH2OWxK
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Amazing meeting organised by Lemmon at the Royal Society- honoured to meet the pioneers in the EGF receptor field! This work has led to so many life-saving drugs - truly inspiring!
James talking at Roy Soc EGFR meeting. Great talk James
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“Queremos estudiar en varios contextos patológicos los diferentes comportamientos que tienen las células endoteliales de un mismo vaso, lo que permitirá avanzar en el conocimiento de muchas enfermedades vinculadas a los vasos sanguíneos”. La Dra. @MarionaGraupera explica en
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@benefactgroup In December, they will be giving 120 charities £1,000 each over 12 days. It would mean so much for my charity @GoPI3Ks to win this so we can continue to help those living with PROS. To nominate please follow this link: https://t.co/DEYFuAicyS thank you ☺️
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With over 1.1M article views in 2023, Biochemical Journal has been at the forefront of exploring the mechanisms of life for over 100 years. Find out more about the journal on our website, and consider submitting your high-impact research https://t.co/47bUYt6cSG
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A meeting to mark 40 years since the EGF receptor was sequenced in Mike Waterfield’s lab at UCL. Promises to be a great meeting and it's free!
royalsociety.org
Discussion meeting organised by Professor Mark A Lemmon FRS.
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Wonderful piece from Gareth and Alexander - I had the pleasure to meet Graham early in my career, an exciting era of major conceptual advances made by exceptional scientist like him, distilled from simple observations and minimal datasets.
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please join us - exciting place to work!
Exciting opportunity to come and work with us @uclcancer @CRUKCOLcentre. We are looking for a Computational Scientist for #proteomics to characterise the regulatory phosphoproteome and apply data integration with other multiomics approaches. #TeamMassSpec
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Manuscript review as it should be!
All Biochemical Journal papers undergo a rigorous peer review process; however, the Editorial Board is committed to ensuring that, if revisions are recommended, extra experiments not necessary to the paper will not be asked for.
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PIPgenerating ART exhibition, 26th sept. Come and join as at Denis Murphy gallery, in Cambridge
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We have some free merchandise at the event, one is for the book lovers out there.📚Inauguration, The Denis Murphy Gallery, 26th September, 16.30, 1-3 Chesterton Rd, Cambridge CB4 3AD. Our other merchandise item will be in our next tweet 😃@PIPgen_ITN
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