CellSig_Lab
@CellsigL
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CellSig is led by Bart Vanhaesebroeck. We aim to improve understanding & drug targeting of the PI3K/PTEN pathway in cancer & beyond. #PI3Kδ #PI3Kactivators
UCL Cancer Institute, London
Joined October 2019
Dear Klaus – thank you very much for your very kind message: you & your CellSig Colleagues made these PI3K discoveries possible, and continue to do so - we now only need more approved PI3K drugs, inhibitors or activators😊. Keep up the good work !.
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RT @Biochem_Journal: Are you interested in the underlying molecular mechanisms of life? Explore the latest completed issue of the Biochemic….
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RT @BatemanLab: Great to see this published and thanks to all 42 co-authors! Including @SilaUltanir @jansen_ac @palneurolab @UKTSA @CellsigL.
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RT @PIPgen_ITN: The dress that visualizes the different cellular markers of an ADPS patient and a healthy person.@M….
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RT @uclcancer: Join the team at UCL and @CRUKCOLcentre 🚀Research Fellow – Computational Scientist for Proteomics. £43,124–£51,610, Full tim….
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RT @Biochem_Journal: Explore our themed collection, Cell Signaling in the 21st Century. This collection captures new developments in cell s….
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RT @NeilVasan: Inavo improves OS - great news for patients. This is the first PI3Ki to improve OS in ER+ MBC. The future is triplets imo….
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RT @Biochem_Journal: Explore our themed collection, Cell Signaling in the 21st Century. This collection captures new developments in cell s….
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RT @Biochem_Journal: Interested in submitting your work to an independent society publisher? Our journals cover the breadth of the molecula….
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Amazing meeting organised by Lemmon at the Royal Society- honoured to meet the pioneers in the EGF receptor field! This work has led to so many life-saving drugs - truly inspiring!.
James talking at Roy Soc EGFR meeting. Great talk James
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RT @CarrerasIJC: “Queremos estudiar en varios contextos patológicos los diferentes comportamientos que tienen las células endoteliales de u….
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RT @MandySellars36: @benefactgroup In December, they will be giving 120 charities £1,000 each over 12 days. It would mean so much for my ch….
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RT @Biochem_Journal: With over 1.1M article views in 2023, Biochemical Journal has been at the forefront of exploring the mechanisms of lif….
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RT @DrSimonCook1: A meeting to mark 40 years since the EGF receptor was sequenced in Mike Waterfield’s lab at UCL. Promises to be a great m….
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Wonderful piece from Gareth and Alexander - I had the pleasure to meet Graham early in my career, an exciting era of major conceptual advances made by exceptional scientist like him, distilled from simple observations and minimal datasets.
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please join us - exciting place to work!.
Exciting opportunity to come and work with us @uclcancer @CRUKCOLcentre. We are looking for a Computational Scientist for #proteomics to characterise the regulatory phosphoproteome and apply data integration with other multiomics approaches. #TeamMassSpec.
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Manuscript review as it should be!.
All Biochemical Journal papers undergo a rigorous peer review process; however, the Editorial Board is committed to ensuring that, if revisions are recommended, extra experiments not necessary to the paper will not be asked for.
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RT @PIPgen_ITN: PIPgenerating ART exhibition, 26th sept. Come and join as at Denis Murphy gallery, in Cambridge
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It has been a huge pleasure working with the Jones team on this: uncovering organismal roles of @PI3K is key to drug intervention, be it in cancer, overgrowth syndromes, immunology, and other disease settings. Congratulations to the team!!!.
Very Happy to come back from holidays and see our latest work published @NatureGenet with the great @Bartomeu_Colom and Phil Jones' team @sangerinstitute! We show how Pik3ca mutant clones expand in the esophagus in a context-responsive way! Thread below👇.
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Wonderful work from @ConduitSarah in @CellsigL - uncovering new #PI3K alpha signalling & #cilia biology!!! Many thanks to our collaborators at @uclcancer @QMBCI @CICbioGUNE @crick @CarrerasIJC and @NatureComms Editor for his professionalism in handling our MS 👋👋.
Pleased to share our work on a new function and signalling pathway for PI3K in primary cilia signalling hubs This adds a new organelle to the PI3K repertoire and could help better understand PI3K’s role in overgrowth syndromes & cancer.
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