Centre for Craniofacial & Regenerative Biology
@CCRB27
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Situated on the 27th floor of Guys hospital in London and part of KCL, our research encompasses development, stem cells, materials-science and bio-imaging 🥼🔬
London
Joined March 2020
We are in the process of migrating away from X. Please follow us at Blue Sky (CCRB27) https://t.co/gWb3QXqzGW or Instagram (CCR_27) https://t.co/KMOuYCKZdX
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Looking forward the group aims to test whether MMP9 inhibition can be used as a therapeutic for improving muscle function in ageing mammals. Congratulations to all authors! Read the paper here: https://t.co/lwhgMoVb6k (3/3)
onlinelibrary.wiley.com
Inhibition of MMP9/13 restores both muSC behaviour and regeneration, while macrophage ablation enhances muSC recruitment to the injury, but fails to improve muscle repair in telomerase-deficient...
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First author Dr. Julie Yue Yuan showed MMP9 inhibition acted on inflammatory cells to promote a more effective migratory response of muscle stem cells, resulting in improved muscle repair in telomerase mutants. (2/3)
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New paper from @CCRB27 out in Aging Cell! Work from Robert Knight’s group showed an exciting effect for a metalloprotease inhibitor in enhancing muscle regeneration in a zebrafish model of accelerated ageing. @kingsdentistry
#Regeneration #Zebrafish #MuscleRepair (1/3)
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This study was led by @ml_basa and recently published at @JournalofAnat @anat_soc It is a collaboration between Abigail Tucker and @NAnthwal at @CCRB27 and @rfelice at @CIA_UCL Congratulations to all authors! #ComparativeAnatomy #Evolution #Snakes #Jaws (3/3)
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Follow the link below for myth-busting snake ‘chin’ descriptions that will leave your mouth agape 🐍😮 https://t.co/hQUYIqMGa0 "The wide gape of snakes: A comparison of the developing mandibular symphysis in sauropsids" (2/3)
onlinelibrary.wiley.com
Our analysis explores the adaptations at the mandibular symphysis required to allow extreme lower jaw mobility in macrostomate snakes taking a comparative approach.
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CCRB paper alert! Most snakes can open their mouths so wide they can consume food that is much larger than their own head. This is partly due to their ‘free’ mandibular symphysis, found to be both bone and cartilage-free. So, how ‘free’ is that symphyseal gap? (1/3)
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To celebrate International Women's Day @IWD2025 we have a new podcast series! We chat to 6 different women for 6 minutes each about the challenges and triumphs of being a #womaninSTEM
https://t.co/hD6YRPpjQy
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Happy (belated) International Women's Day! We are proud to be a woman-led department with 50% women PIs. Representation matters. And we have so many brilliant role models for our students and ECRs. #IWD2025 #AccelerateAction #WOMENINSTEMM
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Happy thanksgiving CCRB. Today we hosted a departmental potluck with dishes from all over the the globe 🌏. The range of food was incredible and so delicious 🤤
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The CCRB annual “summer” party was rained off, but fear not a new event took its place in the form of CCRB olympics! ⚽️🏀🏈 what lab sports would you include?
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We are hiring a new lecturer for CCRB! 🚨 Interested in craniofacial and stem cell biology, innovative approaches to regeneration and repair, and big data approaches to understand the complexity of development and disease. Apply by 6th October
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Congratulations to @OliviaDinwoodi2 @Abigailtuckerk1 and @JuanMFons for having one of the most read articles in @DMM_Journal 👏🏾👏🏾👏🏾👏🏾👏🏾
@owen_sansom @hipp_o_neill @jen_morton Next in line 📚 (3/5) #EditorsChoice
@OliviaDinwoodi2, Abigail Tucker, and @JuanMFons used transgenic reporter mice to track wound healing in the three distinct layers of the tympanic membrane. @KingsCollegeLon @CCRB27
https://t.co/v7j9O8e2lP
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It turns out...Komodo dragons have iron-coated teeth! https://t.co/tcp3GGzXP7 Their serrations and tips pop into the mouth with an orange hue. Using different techniques, we show that these iconic lizards have special iron-rich coatings on each tooth, keeping them razor sharp!
nature.com
Nature Ecology & Evolution - Chemical and structural imaging of Komodo dragon teeth reveals that they maintain their sharp cutting edges through iron-enriched coatings, a unique adaptation...
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Scientists have found Komodo dragons, the largest lizards in the world, have iron coated teeth. @AaronLeBlanc6 (@kingsdentistry) says the study gives us clues to how dinosaurs like the T-rex may have ripped apart their prey #ScienceatKings Read more⬇️ https://t.co/xoiW394BTT
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A massive congratulations to @anna_wulf93 🥳 Everyone in CCRB is very proud!
Congratulations to Dr Anna @anna_wulf93 for a successful PhD viva on ALK/GSK3 and neuroblastoma! Thanks to examiners Dr Greg Findlay @gregfindlaylab and Prof John Anderson/UCL for a great day. @INeucrest @CCRB27
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Well done @MichaelRGDack from @GrigoriadisLab for winning best poster at BRS!
Delighted to have won best poster at #BRS2024 @BoneResearchSoc 🍾 Special thank you to @BCRT for the travel grant, giving me the opportunity to attend and present at the meeting!
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Graduation day!👩🎓 🧑🎓 One of the best days of the year sees our amazing PhD students graduate into Drs. It’s a day to celebrate all their hard work with friends and family👨👩👧 Congratulations to all CCRB’s new doctors!
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@DrDanielDoro and @MichaelRGDack presented our latest work on macrophages in osteosarcoma metastasis at @eu_sarc this week. Lovely to catch up with different colleagues from far and wide. Looking forward to the Meeting in Venice next year!
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Next April I will be running the London Marathon raising money for @BCRT! 🏃♂️ 😰 Please donate using the link below to my just giving page and support this amazing charity 🦴🦴 https://t.co/yZAxnzdHsX
justgiving.com
Help Michael Dack raise money to support Bone Cancer Research Trust
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