DMM Journal
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Disease Models & Mechanisms - discovery for human health. A @Co_Biologists Open Access journal that publishes human disease research.
Cambridge, UK
Joined September 2009
The call for papers deadline for our Special Issue 'In Vitro Models of Human Disease to Inform Mechanism and Drug Discovery' is less than one week away!🚨 We're looking forward to receiving your next paper for this exciting special issue! #OpenAccess
https://t.co/JHlPuyQ4pk
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Read more about this research in our interview with co-first authors Meri Uusi-Mäkelä and Sanna-Kaisa Emilia Harjula at Tampere University, Finland. https://t.co/trM9SvUcOr
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Our immune system uses special structures called inflammasomes to detect and respond to harmful bacteria, including those that cause TB. Uusi-Mäkelä & co use #zebrafish to explore the role of a key inflammasome adaptor protein called ASC/PYCARD. https://t.co/trM9SvUcOr
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Two closely related fungi – Cryptococcus deneoformans (Cd) and Cryptococcus neoformans (Cn) – can cause serious infections. Charles-Niño & co explore how Cd and Cn respond to temperature and how they interact with human tissues, including infection. https://t.co/fcK8sHnQLp
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Read our interview with Caroline Beltran, who conducted this research while a postdoc in Gerhard Walzl's lab at Stellenbosch University, South Africa. https://t.co/Mh6QBdhEvh
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Caroline Beltran & co describe a novel and unbiased 3D imaging approach that visualises how the lung granulomas that are characteristic of TB infection form, evolve & spatially organise. 🐭 🫁 https://t.co/Mg6xQGpjQI
#Tuberculosis #Granuloma
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Bats can carry deadly viruses without getting sick. Now, Ng @WeiLunNg1 & Wang give a timely & fascinating #DMMPerspective on the possible translation of discoveries from bats to humans, in the context of treating and preventing #infectiousdiseases. 🦇🧫 https://t.co/uu5PreL8Nn
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Biological conduction bridges skip a beat ❤️ #preLight (from Theodora Stougiannou) of a study generating stem-cell derived AVN-like pacemaker cells + demonstrating their functionality for biological conduction bridge applications in vivo. @StephIrisPro
https://t.co/75nAZ7haoF
prelights.biologists.com
Biological conduction bridges skip a beat. The preprint authors generate AV node-like pacemaker cells from human pluripotent stem cell populations in order to create a biological conduction bridge.
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The G307D variant of TOM1, an endosomal adaptor protein, is linked to inborn errors of immunity. Ryhänen & co use patient cells to show that this mutation disrupts the interaction of TOM1 with TOLLIP, impairing cargo trafficking & autophagy regulation. https://t.co/kdqqn9yaPg
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Read more in our interview with Victor Tapia, a postdoc research associate in Catherine Lawrence's and Paul Kasher's labs at The University of Manchester, UK, investigating the causes and neuroprotective mechanisms of intracerebral haemorrhage. https://t.co/YKi7nnGNyU
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Using a zebrafish model & human brain tissue, Tapia & co find that high levels of CH25H and 25HC are linked to small brain bleeds following COVID-19 infection. They show that 25HC can damage endothelial cells, especially when cholesterol levels are low. https://t.co/pYLIfMQ06o
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We are delighted to announce the topic for our 2026 Journal Meeting. Save the date and register for abstract updates on 'Innovative Preclinical Models for Pediatric Cancer Research'. https://t.co/3dd3pPprKr
#DMM2026cancer
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Read our interview with Claudia Charles-Niño, a postdoctoral associate in Luis Martinez's lab at the University of Florida, USA, who focuses on understanding molecular interactions between pathogens and the host. https://t.co/WL6OMJhbAz
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Claudia Charles-Niño & co highlight how fungal adaptation to temperature influences disease progression, which is particularly relevant as global temperatures rise. https://t.co/fcK8sHooAX
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The call for papers deadline for our Special Issue 'In Vitro Models of Human Disease to Inform Mechanism and Drug Discovery' is less than one week away!🚨 We're looking forward to receiving your next paper for this exciting special issue. #OpenAccess
https://t.co/JHlPuyQCeS
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Thank you Clare Muir for sharing your experience of fee-free #OA publishing in @DMM_Journal via our #ReadAndPublish agreement @EdUniMainLib @EdUniLibraries @ScienceUoE @SBSatEd Read Clare’s paper: https://t.co/n676H497F8 Is your institution participating? https://t.co/WpJcxTtBmG
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Thank you @DMM_Journal and @Co_Biologists for invitation to this 'At a Glance article' on engineered bacteriophages by Kandas Traore in collaboration with Damien Seyer and Agnes Mihajlovski @UniversiteCergy! Thank you to @EutopiaUni for funding @WarwickLifeSci @uniofwarwick.
In this 'At a Glance' article, Kandas Traore & co highlight how engineered #bacteriophages can be tailored to enhance antibacterial therapies and diagnostics and to support innovative biomedical applications beyond antimicrobial resistance challenges. https://t.co/kEvbganVNh
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In this 'At a Glance' article, Kandas Traore & co highlight how engineered #bacteriophages can be tailored to enhance antibacterial therapies and diagnostics and to support innovative biomedical applications beyond antimicrobial resistance challenges. https://t.co/kEvbganVNh
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You can read about Godwin's experience of the one-day programme on antimicrobial resistance at the Biologists @ 100 conference here:
biologists.com
26 June 2025 by Godwin Pius Ohemu Godwin Pius Ohemu is an MSc graduate in epidemiology from the University of Port Harcourt, Nigeria, and holds a Postgraduate Diploma in Global Health Research from...
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Our next extraordinary biologist is Godwin Pius Ohemu, who attended the Biologists @ 100 conference and shared his conference experience in a guest blog. #100biologists
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