Sabine Brumm
@BrummSabine
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Research & Teaching Assistant in the process of establishing junior research group at Phytopathology TUM Freising; Interests: Plant-microbe interactions
Likes to travel the world
Joined November 2018
How do plants fine-tune their development at the molecular level? In our latest study we uncover that intrinsically disordered regions play a crucial role for the functional diversification of actin regulatory Medicago SCAR proteins 🚨PrePrint alert 🧵1/9
biorxiv.org
Dynamic actin cytoskeleton reorganisation enables plant developmental processes requiring polarised transport such as root hair and leaf trichome formation. The SCAR/WAVE complex plays a crucial role...
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For more information, please see the attached advert picture or visit: Feel free to contact me if you have any questions. We will start reviewing applications from the 10th of July onwards.
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Please RT: Open PhD Position @TUM @HuckelhovenR (Freising, Germany) Join our team and help us to decode the molecular mechanisms driving plant cell remodeling during fungal infection. Focus: RICs in Barley–Blumeria hordei interaction 🔬 CRISPR, microscopy, proteomics & more
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RT @dromius: What does this look like to you?.This is #Phytophthora palmivora (magenta) infecting roots of barley seedlings. All roots are….
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Amazing people. Glad I got to know all of you.
New Year's Lunch 2025. Happy to be doing research with this team (Isaac Coven, @kos_darius, Matthew Macleod, @Nick_GarciaH, @alan_wanke, @AlexWGuyon. @Rochirmayi, @IamJawaharSingh, & Karen Uchida. @AlbinTeulet and @theduck12908145 are missing on this pic.
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RT @biorxiv_plants: Engineering an Exo70 integrated domain of a barley NLR for improved blast resistance #biorxiv_….
biorxiv.org
Intracellular immune receptors protect plants from microbial invasion by detecting and responding to pathogen-derived effector molecules, often triggering cell death responses. However, pathogen...
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Wrapping up 5 years of research. Left: Barley seeds. Right: Arabidopsis, Benthi and Medicago…bigger seeds means much more storage space needed 😅
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RT @neha_bhatia29: Post-doc position available in my lab at SLCU. If you are passionate about plant development, live imaging and learning….
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Amazing position open in Sheffield. Jim is not only an amazing scientist but also a very kind human. Can 100% recommend working with him.
The Rowe lab is recruiting a #PlantScience PhD student for 2025! You'll use our new ABACUS FRET biosensors to map the dynamic leaf #AbscisicAcid accumulations at low humidity in Arabidopsis, wheat and rice. #PhDposition.
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Uh, it’s online now 🎉. Congratulations to all of you! Amazing work!.
I am very excited to be sharing our new @dromius lab pre-print on a Marchantia gene MpGRAS7, with contributions from @Phil_Carella and @YangWeibing
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RT @AlbinTeulet: 🎃 Our Halloween pumpkin carving contest brought out some amazing creations, but Pumpkin Jail took the top prize! 🏆.@slcupl….
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One of my new favorite websites/resources: Huge thank you to the developers and everyone involved in bringing the genomes together. It’s amazing to have a resource that’s so easy to navigate and extract information from. 🙏 #barley #plantscience 🔎🧬.
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Ullswater Lake in the Lake District, England. Stunning location for a symposium. Looking forward to learn more about root and gut microbiomes at the Rank Symposium the next couple of days. Grateful they also scheduled time for a hike through this amazing landscape tomorrow.
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RT @biorxiv_plants: The genetic basis of replicated bullseye pattern reduction across the Trionum Complex #biorxiv….
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RT @ZMBP_Tuebingen: Job alert 📢.We are looking for a new Independent Junior Group Leader in plant molecular biology @ZMBP_Tuebingen! .Submi….
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Congratulations to everyone! 🎉.
Hot off the press! .A great colab with the @Tolga_Bzkrt team led by @EnochYuen - feat. the P. palmivora effector TIKI (trafficking interference & tissue-killing) and its target TOPGAP (a RabGAP) studied by @edouard_evan & @TulinFrej.
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RT @brockingtonian: JOB ALERT. I’ve have been waiting to offer this for ~10 years. We’re hiring an Expeditionary Botanist to lead our exped….
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Last but not least: Science is a team effort, and this work wouldn’t have been possible without the contributions and support of many! A huge thank you to our amazing co-authors, technical support teams, students, collaborators and funders for their dedication and support.🧵9/9
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What does this mean in broader context? We discuss the possibility that functionally diverse SCAR/WAVE subcomplexes could exist which would overall allow greater diversity in actin regulation across various cellular contexts. 🧵 8/9
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Discussion: Generally, IDRs are also known to act as interaction surfaces. They may contribute to SCAR functionality by fine-tuning protein stability through differential interactions with other proteins. 🧵7/9
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Interestingly, one of this short amino acid sequences decreases protein abundance across different proteins, species and tissue contexts. Example: its fusion to mCitrine leads to a significant decrease of mCitrine protein but not transcript levels in N. benthamiana leaves. 🧵6/9
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