BrittonLab
@BrittonLab
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Group run twitter account for the Britton Organic Chemistry Lab
Simon Fraser University
Joined November 2021
The Britton Group is looking for new Postdoctoral Researchers! Come join our team at @SFU to get involved in the excited chemistry we do. Interested applicants please contact Dr. Britton (details here https://t.co/IZi6OQ74r1). Hope to hear from you soon! #chemtwitter #chemjobs
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A handful of group members had the chance to represent the lab with some excellent poster and oral presentations in beautiful Banff, Alberta this past week! Thank you to the @BanffSOC committee for organizing such a fun and interactive conference! #chemtwitter
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Congratulations to Ethan for his published review on "Non-carbohydrate syntheses of nucleoside analogues", featuring our group's research on the synthesis of ribo-, imino-, thio-, and carbocyclic nucleoside analogues from simple achiral precursors! https://t.co/atMs2kqLyr
cell.com
Nucleoside analogues (NAs) continue to be a rich source of antiviral and anticancer drug leads and critical components of oligonucleotide therapeutics (ONTs). To support drug development, significant...
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Welcome to our newest PhD student Peter! We had a fun group outing last week to celebrate, enjoying some brews and pizza at Rewind Brewery :) #chemtwitter #teambonding
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New publication out in @angew_chem on the "Synthesis and Diversification of Bridged Nucleoside Analogues" in collaboration with @Merck, @DrLCsquare, and @asymtmm ... check it out! #chemtwitter #nucleosides
https://t.co/aR1zW5LQ54
onlinelibrary.wiley.com
Several processes are reported that enable the rapid diversification of bridged nucleoside analogues (NAs) starting from a common and readily prepared fluorohydrin. Also, several clinically relevant...
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Thank you to the @Stephenson_Lab for hosting us @UBC for our first joint group meeting! We enjoyed learning about the photoredox/electrochemical research your team undertakes and were excited to share a glimpse into our nucleoside/total synthesis research with you! #chemtwitter
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Check out our latest publication in collaboration with @BCCancer featured in JACS!!! Big congratulations to Dr. Daniel Driedger as this was a substantial portion of his PhD thesis! This synthesis of Eleutherobin has been a long time coming (> a decade)!!! https://t.co/tX8CUauoYN
pubs.acs.org
The eleutherobins and sarcodictyins are diterpenoids that belong to an elite family of microtubule-stabilizing natural products that includes the frontline cancer therapy Taxol. To date, members of...
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We enjoyed an amazing BBQ outing yesterday at Strathcona Lookout Park in Deep Cove! The day was filled with fun on the water in paddle boards and canoes (thanks Rob!) along side some competitive spike ball games in the park :) #chemtwitter #teambonding
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Congratulations to Daniel and Darryl for an excellent publication in @ChemicalScience !!! Showcasing an exhaustive and impressive chemical library of 170 polypeptide-like macrolides ... well done! #chemtwitter
https://t.co/YcCK9547mj
pubs.rsc.org
Polyketide-like macrolides (pMLs) represent a privileged class of compounds with a high incidence of bioactivity, however their structural complexity challenges their synthesis and more general...
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Congratulations to Dr. @GarrettMuir (and other Britton lab co-authors) for this interesting investigation of Grignard reactions to C4'-modified nucleoside analogues in collaboration with @Merck , @DrLCsquare , and @asymtmm ... Excellent work everyone! https://t.co/2bINEvR9rB
nature.com
Nature Communications - The Grignard reaction represents one of the most powerful carbon-carbon bond forming reactions and is the subject of continual study. Here, the authors report a halide...
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Britton Lab Christmas Dinner 2024 complete with delicious food from @CRAFTbeermarket and a fun Pirate Santa game🎁🎅🏼 with plenty of 'gift-stealing' (mainly the special cereal and lotto tickets). Merry Christmas and Happy Holidays from our lab to you and yours! #chemtwittter
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Fresh article out now in @ChemicalScience !!! Well done to the team for the hard work put towards this exciting project! Yet another example of how ɑFAR aldol products are excellent and diversifiable precursors towards nucleoside analogues. #chemtwitter
https://t.co/OUNvScdemf
pubs.rsc.org
4′-Thionucleosides (thNAs) are synthetic nucleoside analogues that have attracted attention as leads for drug discovery in oncology and virology. Here we report a de novo thNA synthesis that relies...
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Congratulations to Rob for this exciting achievement and recognition! #chemtwitter
The Bernard Belleau Award is presented to a scientist who has made a distinguished contribution to medicinal chemistry through research involving biochemical or organic chemical mechanisms. Congrats @brittonlab of @SFU on being the recipient of this award. https://t.co/aUAv5Xw2qd
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We recently had a celebration for Simha, a former post-doc in the lab who secured a position at @GileadSciences !!! Thank you Simha for being an excellent leader in the group and an exemplary chemist and experimentalist. All the best in your future endeavours! #chemtwitter
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A delicious welcome lunch at SFU's dining commons (HQ) for new graduate students Megan, Breanna, and Olises and new post-doc Mamda. #chemtwitter
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Congratulations to our very own Dr. @GarrettMuir for his now published work on the synthesis of the phormidolide A macrocycle, recently out in @JOC_OL !! #chemtwitter
Now out in @JOC_OL, we report the synthesis + stereochemical confirmation of the phormidolide A macrocycle. This is a true collaborative venture with the @BrittonLab that has taken many twists and turns (1/2) @SFUChemistry @ChemCambridge @chemistryatuvic
https://t.co/WrsBmWGuXc
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For #GBW2024, let's throw back to an exciting breakthrough by @Vocadlogroup & @BrittonLab! Their sugar-blocking tech for developing therapeutic antibodies to target cancer is being commercialized by GlycoNet-supported startup Carbaform. Read more: https://t.co/1fwm8X3O20
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Congratulations to Suping for recently successfully defending his masters thesis! During his time in the Britton lab, Suping developed some elegant chemistry towards the synthesis of some complex nucleoside analogues. We're very proud of you Suping! #chemtwitter #mastersdefense
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Guillermo presented his work on the formal synthesis of eribulin at the Mexican Academy of Organic Chemistry annual conference ( @AMQO_mexico ) recently! He also did a TV interview to share what a Chemistry PhD does for a living... Way to represent the group well! #chemtwitter
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Some lab members ditched the lab to enjoy a beautiful day on Bowen Island yesterday! A perfect way to end off the week ☀️ #chemistswhohike #chemtwitter
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GlycoNet investigators @VocadloGroup and @BrittonLab at @SFU have created a sugar-blocking technology that “supercharges” antibodies to target cancer more effectively. Read more: https://t.co/5xYOq3ZlRU
#glycotime #glycomics #research #science @SFUresearch @mbbsfu
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