Brian Tsu
@BriBerryTea
Followers
127
Following
2K
Media
2
Statuses
169
Thunder, Birds, comp bio with a focus on host-viral evolution | Bash, R, Python lang, dogs, and running fanboy (he/him)
United States
Joined November 2016
RT @underthelenns: Excited to see that our review on tripwire effector-triggered immune sensing of viral proteases by CARD8 & NLRP1 is out!….
0
7
0
RT @Daugherty_Lab: Our paper on CARD8-mediated sensing of infection by SARS-CoV-2 (and other coronaviruses and picornaviruses) is now out i….
journals.plos.org
This study describes an innate immune mechanism for sensing coronavirus and picornavirus infection by detecting the activity of virus-encoded proteases. Genetic variants among mammalian hosts affect...
0
18
0
RT @Daugherty_Lab: New paper out in PNAS about how the ability of vertebrates to see is in part due to a gene we acquired from bacteria. ht….
pnas.org
The vertebrate eye was described by Charles Darwin as one of the greatest potential challenges to a theory of natural selection by stepwise evoluti...
0
141
0
RT @clairemlchapman: We rotate together, we join labs together, we get fellowships together! @andrew_kapinos is officially my PhD buddy for….
0
5
0
RT @Neal_Lab: Our paper on "An ERAD-independent role for derlin Dfm1 in maintaining sphingolipid homeostasis" is now out in @embojournal! C….
embopress.org
image image Previously, yeast derlin Dfm1 was found to be critical for retrotranslocating integral membrane substrates targeted for ER‐associated degradation (ERAD). This study reveals an ERAD‐inde...
0
21
0
RT @lizfay20: I dessed as the Red Queen Hypothesis for Halloween this year. I was only missing a treadmill (so I could do all the running I….
0
4
0
RT @Daugherty_Lab: Our paper using evolution to find an antiviral role and viral antagonism of NINL is now published in eLife! https://t.co….
elifesciences.org
Evolution-guided functional analyses identify an activating adaptor of the dynein intracellular transportation machinery, NINL, as a novel component of the antiviral immune response and reveal a...
0
16
0
RT @Neal_Lab: It’s takes a village to launch a dream program like @bummp_ucsd. An amazing team of leaders who will fight tooth and nail for….
0
3
0
RT @Daugherty_Lab: New preprint out showing a cool new host- and virus-specific way that the immune system has evolved to sense coronavirus….
biorxiv.org
Hosts have evolved diverse strategies to respond to microbial infections, including the detection of pathogen-encoded proteases by inflammasome-forming sensors such as NLRP1 and CARD8. Here, we find...
0
29
0
RT @ChinmayK98: I met my science hero @HarmitMalik today!! Such a warm and inspiring person, my academic grandpa from @Daugherty_Lab! https….
0
4
0
RT @ucsdbiosciences: Congratulations to BioSci graduate student Lennice Castro and her advisor Matt Daugherty on receiving a Howard Hughes….
0
8
0
RT @underthelenns: I am a 2022 HHMI Gilliam Fellow! 🥳. Huge thanks to my amazing mentor Matt @Daugherty_Lab who believes in me even when my….
0
12
0
RT @Daugherty_Lab: Extremely proud of Lennice Castro @underthelenns (front and center in the photo below) for being named an HHMI Gilliam F….
0
4
0
RT @Daugherty_Lab: New preprint from my lab and @SamReckPeterson lab describing our evolution-guided discovery of a new host-virus conflict….
biorxiv.org
Viruses interact with the intracellular transport machinery to promote viral replication. Such host-virus interactions can drive host gene adaptation, leaving signatures of pathogen-driven evolution...
0
32
0
RT @yeo_lab: Thank you @Pasquinelli_Lab for a fun collaboration to identify RNAs bound by nuclear and cytoplasmic poly(A)-tail binding prot….
academic.oup.com
Abstract. The poly(A)-tail appended to the 3′-end of most eukaryotic transcripts plays a key role in their stability, nuclear transport, and translation. T
0
23
0
RT @Daugherty_Lab: Congratulations to Lennice Castro (@underthelenns) for being awarded a Ford Foundation Predoctoral Fellowship! Such a gr….
0
6
0
RT @underthelenns: I was happy to get honorable mention last year, and I am THRILLED to say that after applying for the second time I have….
0
5
0
RT @Sonia_Kang: The greatest trick that #academia ever pulled is convincing young impressionable grad students that living close to family….
0
490
0