Brad Sutherland
@BradASutherland
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Associate Professor, Neurovascular Scientist, University of Tasmania. Views are my own.
Hobart, Tasmania
Joined June 2020
Find out more about #ANS2025 symposia for the Hobart 2025 ANS meeting including "New insights into the roles of cerebrovasculature in nutrient supply, waste removal, neurodegenerative diseases and beyond" here: https://t.co/9ztAE2SgYi
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🗣️Calling all ANS members to nominate symposia and speakers for the #ANS2025 conference to be held in Hobart, Tasmania, from 30 Nov-3 Dec! Symposium guidelines: https://t.co/urIErpDeVy Submit porposal here: https://t.co/rw2MBsHIqZ But hurry! Submissions close 5pm, 24/03/2025
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Can't wait for next year's @AusNeuroSoc meeting in Hobart! The conference is in great hands with @ziebs83 @BradASutherland
🥁🥁🥁🥁 It is official and Tasmania will host the ANS 2025! Hope you all can attend! @AusNeuroSoc @ANS_Students @_hellewell_
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🧠🔬 Exciting #HotTopic: microglial "plugs" found at blood vessel contacts in the brain! This opens a new path to understand how microglia interact with the vasculature in health and disease. Don't miss it: https://t.co/6WRsQlU25V
#JCBFMhome #ISCBFM #BrainResearch
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Our new paper published in @BrainBehavImm shows ablating pericytes in mice causes hypoactivity🏃, motor impairment, vessel dysfunction🩸, and widespread gliosis🌟. Another reminder of how important pericytes are for brain function. @BradASutherland @LabGlial (1/3)
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Excited to share that our work showing the #mTOR inhibitor #rapamycin (Sirolimus) can reduce #brain #pericyte constriction following #stroke, is now published in Translational Stroke Research!
link.springer.com
Translational Stroke Research - The contraction and subsequent death of brain pericytes may play a role in microvascular no-reflow following the reopening of an occluded artery during ischemic...
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1/4 We are thrilled to announce that our 🌍 collaboration has resulted in a paper in @_JCBFM. @Gazz4_Science @CathFoster_ @BradASutherland @UTAS_ @SeattleChildrens @uni_copenhagen
https://t.co/Wzp9CHnXtO
journals.sagepub.com
The close spatial relationship between microglia and cerebral blood vessels implicates microglia in vascular development, homeostasis and disease. In this study...
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I am pleased to launch the Multiple Sclerosis Centre of Research Excellence, funded by the NHMRC. I look forward to working with Bruce Taylor, @williamreay96 , Ingrid van der Mei, @aydzhouyuan , @BradASutherland , Jake Gratten, @NatashaJStevens , Leonid Churilov & Chris Gumley
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Numerous pharmacological studies modulating pericyte contraction are currently being published! 👀 This interesting @biorxivpreprint shows that #Rapamycin (#mTOR inhibition) relaxes #pericytes, mitigating capillary dysfunction after stroke reperfusion 🧠 https://t.co/m555pRjAdj
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Excited to share our new preprint showing that the #mTOR inhibitor #rapamycin (Sirolimus) can reduce #brain #pericyte constriction following ischemia in vitro and #MCAO #stroke in vivo. https://t.co/xAxfD2f2Io.
biorxiv.org
The contraction and subsequent death of brain pericytes may play a role in microvascular no-reflow following the re-opening of an occluded artery during ischemic stroke. Mammalian target of rapamycin...
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Check out our new work on how microglia interact with the vasculature through astrocyte end feet using the @AllenInstitute #MICrONS cortical mm^3 dataset! Had a great time working with @Gazz4_Science, @BradASutherland and @SorenGrubb to produce this work!
1/ 🔥 Exciting findings from our collaboration between @UTAS_, @SeattleChildrens, and @uni_copenhagen! We've discovered a new way #microglia interact with 🧠 vasculature, which could reshape our understanding of their role in #brain health and disease. 🧵 https://t.co/iaNFHuURPg
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1/ 🔥 Exciting findings from our collaboration between @UTAS_, @SeattleChildrens, and @uni_copenhagen! We've discovered a new way #microglia interact with 🧠 vasculature, which could reshape our understanding of their role in #brain health and disease. 🧵 https://t.co/iaNFHuURPg
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Our latest publication was just released in Stem Cell Research and Therapy, showing gene expression and functional differences between neural crest and mesoderm iPSC-derived pericytes (iPericytes). Check it out here:
stemcellres.biomedcentral.com
Background Pericytes are multifunctional contractile cells that reside on capillaries. Pericytes are critical regulators of cerebral blood flow and blood–brain barrier function, and pericyte dysfun...
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📢Our lab https://t.co/nmcWR101V0 at @QldBrainInst is looking for a PhD student interested in brain oscillations and their intricate role in restoring function after stroke. Lots of cool techniques such as in vivo electrophysiology and imaging in🐭. Info:
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We invite applications for a postdoctoral position with the Glial Research Team in Hobart, Australia. Please apply online by following this link. https://t.co/LAX7MiMeN3
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Delighted to be awarded an @nhmrc Ideas grant investigating pericytes, microglia and blood vessel breakdown in Alzheimer's Disease. Looking forward to working with Gary Morris, @ziebs83 and @group_deluca and collaborators on this exciting project. @UTAS_MedSci @WickingDementia
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We look forward to starting work on our NHMRC Ideas grant with @FletcherJL, @nickomatics, @BradASutherland and @BruestleLab. Together we will find out how MS-associated genetic variants alter brain cell function.
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Fabulous talk by @BradASutherland at @AusNeuroSoc 2023 in #Brisbane about #pericytes and #microglia in health and disease. @UTAS_ @UTAS_MPH
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Sometimes #pericyte cell culture can get #spooky. Is this #perinormal activity? #HappyHalloween 🎃💀 https://t.co/IwvwB06NB9
@BradASutherland @NatKingScience @jomaree @Jake_Cashion_
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📢 Exciting news - my latest preprint exploring the impacts of pericyte ablation on behaviour and brain health is out! 🧠🩸🐭 https://t.co/z5sxZT7tBG
@BradASutherland @LabGlial Pericytes 🟣 Vessels 🟢 #pericytes #neuroscience (1/3)
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