Bigas/Espinosa Lab
@BigSpinLab
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🔬Research Group focused on Stem cells and Cancer at @HMar_research @CarrerasIJC 👩🔬👨🔬 Dr. Anna Bigas and Dr. Lluís Espinosa working together since 1998
Barcelona
Joined July 2019
Happy to share our minimal fetal-like gene signatures (ColoStem & EpiColoStem) that identify high-risk colorectal tumors in >1,100 patients and are measurable by qPCR in tissue and plasma, enabling patient stratification for future targeted therapies. https://t.co/euQBOf04TF
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Desxifren els esdeveniments genètics que desencadenarien una leucèmia en pacients d’un trastorn rar: la deficiència en GATA2🧬 L’estudi s’ha fet gràcies a models avançats del trastorn fets pels investigadors, una eina clau en la recerca d'ara endavant 👉 https://t.co/nFCXTZZAnf
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La Dra. Anna Bigas, investigadora @HMar_research i @CarrerasIJC, s'incorpora com a #editoraassociada a @Dev_journal📰 Està centrada en el camp de la biologia del desenvolupament i malalties associades a processos embrionaris @Co_Biologists @BigSpinLab
https://t.co/e66Z6mJyKR
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We are delighted to welcome Anna Bigas (@BigSpinLab) from Hospital del Mar Research Institute and Josep Carreras Leukemia Research Institute as a new Associate Editor at Development, handling papers on #haematopoiesis, #signalling and #cancer. https://t.co/QGK39bvOwp
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Check out this new research from the @BigSpinLab! The authors found that IκBα accumulates specifically in the chromatin fraction of mPSCs. 📚 More in @eLife: https://t.co/zau5JFap9E
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🩸Desarrollan modelos de embrión en laboratorio que producen células sanguíneas 🗨️Anna Bigas @BigSpinLab: "Es un trabajo muy preliminar que sugiere que, con las condiciones adecuadas, seremos capaces de obtener muchos tipos celulares" https://t.co/0XnPWkbDCd
sciencemediacentre.es
Un equipo liderado por la Universidad de Cambridge (Reino Unido) ha utilizado células madre humanas para producir estructuras tridimensionales similares a embriones que replican ciertos aspectos del...
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It's always a pleasure to work together!🔬👩🔬
New paper from our lab finally online 🔥. Congrats to the amazing first author 👏🏽 @Fra_Matteini💥, wonderful collaborators Anna Bigas @BigSpinLab and Antonio Del Sol @delSolLab Stem Cell Aging Team @idibell_cat 👇🏽👇🏽👇🏽 Notch in HSC aging https://t.co/K6JcGzKvaO
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New paper from our lab finally online 🔥. Congrats to the amazing first author 👏🏽 @Fra_Matteini💥, wonderful collaborators Anna Bigas @BigSpinLab and Antonio Del Sol @delSolLab Stem Cell Aging Team @idibell_cat 👇🏽👇🏽👇🏽 Notch in HSC aging https://t.co/K6JcGzKvaO
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📢New Workshop on NF-kB: Cell Plasticity and Cancer 📅 Tues 23 Sep ⏰ 9.30 h 📍 Charles Darwin Room The workshop will feature presentations from a range of distinguished experts in oncology research ℹ️ https://t.co/6fJY8lhGJi
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Thrilled to share with you the latest work from my PhD in @BigSpinLab @HMar_research @CarrerasIJC published in @BloodPortfolio We’ve programmed blood stem cells from PSCs using CRISPRa screen and found a new “bloody” cocktail #CRISPR #HSCs #StemCells
https://t.co/uuPoD5C0hL
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🚨New paper out!🚨 🔬 CRISPRa screening during mesodermal differentiation identifies 7 key genes with HSC induction potential. 🧬 A 7-gene cocktail drives multilineage repopulation and self-renewal from mouse ESCs. 📄 Don’t miss it! https://t.co/vHQPJ7FxtU
ashpublications.org
Key PointsCRISPR activation screening during mesodermal differentiation from mouse embryonic stem cells identifies 7 genes with HSC induction potential.A c
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🔬 Join us for the next @hmar_research-@UPFbiomed Seminar! 🗓️15/07 📌Charles Darwin Room Talks by @bigas_anna @BigSpinLab & @AMartinezArias @icreacommunity 👉 https://t.co/NHLo3ABisf
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🚀 New paper out! 🔬Discover how IκBα exerts distinct chromatin- and NF-κB-related regulatory functions, and how its chromatin-related activity restores intestinal stem cell function & differentiation 👉 https://t.co/EJGECOjfG6
cell.com
Daniel Álvarez-Villanueva et al. dissect distinct roles of the NF-κB inhibitor IκBα by generating separation-of-function mutants. Their findings reveal that chromatin-bound IκBα, independent of NF-κB...
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💬 "Som més a prop del somni científic de crear sang artificial amb finalitats terapèutiques"🩸 🔬📺 La recerca del @BigSpinLab, a les notícies de @som3cat ➡️
3cat.cat
Un equip de l'Hospital del Mar ha identificat set gens que permeten crear cèl·lules mare sanguínies
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A step closer to the confident production of #bloodstemcells for regenerative medicine Study published in @BloodJournal, from @BigSpinLab, @HMar_research and @CarrerasIJC
@ASH_hematology @Menendez_Lab @clarabueno_74 @CienciaGob @recercauniscat
https://t.co/PYj1CJLGtE
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Happy to share that our work ‘An unbiased genomewide screen uncovers 7 genes that drive hematopoietic stem cell fate from mouse embryonic stem cells’ as first edition in @BloodJournal. Thank you to all collaborators for making this work possible! https://t.co/LZ4llxGhm3
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🔊New paper out🔬 Click here to know more about how NEMO targets the ATM/IKKα complex to sites of DNA damage, enhancing DNA repair and chemotherapy resistance! https://t.co/HhkzV9eHsG
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New european project to erradicate fetal type tumors! Thanks to all EP PerMed people 🔍🔬🥂❤️
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🔬 Join us for the next @hmar_research - @UPFbiomed seminar 📅18/02 | 🕛 12:00h📍 Charles Darwin Room Featuring: 🎙️ Lluís Espinosa @BigSpinLab @hmar_research 🎙️ @bertaalsina @UPFbiomed
@hospitaldelmar @the_prbb
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400 expertos nacionales e internacionales participarán en el congreso "La Semana de la Ciencia en Cáncer", un espacio que busca fortalecer las conexiones entre científicos. 🎙️ @DeborahSR5
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