
Birmingham Clinical Trials Unit
@BhamCTU
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Fully registered clinical trials unit specialising in the design, conduct and analysis of definitive clinical trials and test evaluation studies.
Birmingham, England
Joined August 2018
The views and opinions expressed therein are those of the authors and do not necessarily reflect those of the NIHR, NHS or the DoH.
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CReST showed that stenting as a bridge to surgery reduces stoma formation without detrimental effects in colon cancer patients with left-sided colonic obstruction #ICTD2023 @BJSurgery
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Recruiting from 80 hospitals in 7 global south countries, @CheetahRct found that 1 in 8 surgical site infections could be prevented by changing gloves and instruments before fascial closure for abdominal surgery @TheLancet @NIHR_GSU #ICTD2023
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The @STOPACEi_trial showed that in people with advanced and progressive chronic kidney disease, discontinuation of RAS inhibitors was not associated with difference in rate of decrease in kidney function measured using eGFR @NEJM #ICTD2023
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Published in @JCO_ASCO, FOxTROT showed that six weeks of preoperative chemotherapy for operable colon cancer can be delivered safely and provides better 2-year disease control #ICTD2023.
ascopubs.org
PURPOSENeoadjuvant chemotherapy (NAC) has potential advantages over standard postoperative chemotherapy for locally advanced colon cancer but requires formal evaluation.METHODSPatients with radiolo...
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Funded by @gatesfoundation, the @EmotiveTrial cluster randomised trial showed an immense 60% reduction in severe postpartum haemorrhage after vaginal delivery, reducing the risk of haemorrhage-related maternal death @NEJM #ICTD2023
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BCTU, a UKCRC registered trials unit was 25 years old in 2022. Clinical Trial Units play a key role in the design and delivery of clinical trials. To celebrate #ClinicalTrialsDay we will be tweeting about some of the trials we have delivered over the past 12 months.
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RT @KKCheng4: Proud beyond words of the work of colleagues from @unibirmingham. @unibirm_MDS @IMSR_UoB @UoB_IAHR Partnering with the @WHO a….
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RT @BillGates: I’m very encouraged by the E-MOTIVE Trial results released today at #IMNHC2023 to treat postpartum hemorrhage, the #1 cause….
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If anyone is interested to know more about FOxTROT, @JenSeligmann's tweetorial is essential Friday lunchtime reading!.
🥁🥁🥁Tweetorial .FOxTROT, the 1st ph 3 RCT of neoadjuvant chemo (NAC) in locally advanced colon cancer .We report that NAC is.✅deliverable and safe.✅led to statistically significant reduction in cancer recurrence than upfront surgery.A 🧵 (1/14).#crcsm.
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RT @JenSeligmann: 🥁🥁🥁Tweetorial .FOxTROT, the 1st ph 3 RCT of neoadjuvant chemo (NAC) in locally advanced colon cancer .We report that NAC….
ascopubs.org
PURPOSENeoadjuvant chemotherapy (NAC) has potential advantages over standard postoperative chemotherapy for locally advanced colon cancer but requires formal evaluation.METHODSPatients with radiolo...
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RT @DrJamesGlasbey: Lots of questions emerging about #obstructionrisk in @FoxtrotStudy #NAC group❓. We've done a deep dive into this in upc….
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RT @CR_UK: 📢 News: FOxTROT, a trial we funded, has shown that starting chemotherapy before surgery, instead of after, can significantly cut….
news.cancerresearchuk.org
Giving colon cancer patients chemotherapy before surgery cuts their risk of the disease coming back, according to a trial we funded.
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Thank you to @guardian @GdnHealthcare for featuring the FOxTROT trial results in today's publication!.
theguardian.com
UK trial across three countries finds that giving patients chemotherapy before surgery was more effective
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But that's not all! FOxTROT-2 and 3 are currently active and further researching neoadjuvant chemotherapy in colon cancer. You can find out more at @FoxtrotStudy @LeedsCTRU.
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FOxTROT lead investigators Dion Morton, @seymourmatt1 & Richard Gray. @JenSeligmann @DrJamesGlasbey. Bengt Glimelius & Søren Laurberg. @CR_UK @yorkshirecancer @BobbyMooreFund. #colorectalcancer #clinicalresearch #cancerresearch #bowelcancer #neoadjuvant #foxtrot.
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FOxTROT-1 trial results have been released by @JCO_ASCO!. ✅Pre-operative chemotherapy for locally advanced operable colon cancer is safe.✅Improved histopathological & oncological outcomes.✅Reduced 2-year recurrence .
ascopubs.org
PURPOSENeoadjuvant chemotherapy (NAC) has potential advantages over standard postoperative chemotherapy for locally advanced colon cancer but requires formal evaluation.METHODSPatients with radiolo...
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Our trials WILL, iHOLDS, Giant PANDA and CAPE are all being exhibited at the BCTU stand at #BMFMS at Birmingham's Millennium Point today. Come and speak to the teams for more information on these exciting trials #clinicaltrials #WomensHealth
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