Bruno Lopes Bastos
@BLopesBastos
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Postdoctoral researcher interested in cancer and aging using zebrafish as a model 🇳🇱🇵🇹
Den Haag, Nederland
Joined April 2020
The main study from my postdoc @MGodinhoFerr is out! #Telomerase isn't required for tumor initiation but its lack drives #Cancer #regression later. Regression occurs via tumor-autonomous mechanisms (cell cycle arrest, apoptosis, melanocyte differentiation) and immune rejection.
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RT @imperialcollege: We’ve been named as 1st in the UK and 2nd in the world by QS @worlduniranking! . This recognises Imperial as one of th….
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RT @BLopesBastos: Thank you @preLights and @sandaklyj for highlighting our work! In our latest preprint, we show that blocking telomeric DN….
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Thank you @preLights and @sandaklyj for highlighting our work! In our latest preprint, we show that blocking telomeric DNA damage with antisense oligonucleotides can delay premature aging in zebrafish.Check out their great summary below 👇.
In my latest @preLights post, I highlight this recent work by Giulia Allavena et al. in which the authors find that blocking telomeric DNA damage pathway using antisens oligonucleotides reduces premature aging in zebrafish 🐟🧬. Check it out.
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RT @sandaklyj: In my latest @preLights post, I highlight this recent work by Giulia Allavena et al. in which the authors find that blocking….
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RT @RVfanfaron: A new article from @MGodinhoFerr @ircaninstitute @Univ_CotedAzur shows an important impact of STING signaling on aging u….
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RT @MGodinhoFerr: Join us in Lisbon for the GIMM Festival: #Aging and #Longevity, happening September 4–6! Explore the future of aging with….
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RT @organelletx: 🐟⏳ Aging Triggered from Within!. cGAS-STING pathway drives premature aging in telomerase-deficient zebrafish — linking imm….
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RT @cell_club: cGAS-STING are responsible for premature aging of telomerase-deficient zebrafish | The EMBO Journal
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Check out out latest publication!!.Where we show that #cGAS–#STING inflammation drives premature #aging in response to telomere shortening in #zebrafish.
Happy to share our new paper! 🎉.We show that #cGAS–#STING inflammation drives premature #aging in response to telomere shortening in #zebrafish. 🧬 Telomere-driven aging occurs in 2 stages:.1️⃣ Senescence, inflammaging, cancer.2️⃣ Genome instability, death.
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RT @MGodinhoFerr: Happy to share our new paper! 🎉.We show that #cGAS–#STING inflammation drives premature #aging in response to telomere sh….
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It's super exciting to see The Longevity Papers podcast discuss our recent preprint at [15:50]—highlighting the long-lasting effects of a single-dose treatment in #zebrafish. In their own words: the results are pretty remarkable! .Check it out: #longevity.
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RT @BLopesBastos: Excited to share our latest preprint! We show that telomeric antisense oligonucleotides alleviate premature #aging in tel….
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Excited to share our latest preprint! We show that telomeric antisense oligonucleotides alleviate premature #aging in telomerase mutant #zebrafish. A great collaboration with the labs of @MGodinhoFerr, @FdAdF66 and @MarinaMione.
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New paper out! "Peptide-Modified Lipid Nanoparticles Boost the Antitumor Efficacy of RNA Therapeutics".Engineered LNPs with peptides enhanced RNA delivery and improved cancer treatment. #RNAtherapeutics #CancerResearch #LipidNanoparticles #zebrafish
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Zebrafish Against Cancer: Towards Clinical Relevance.Join our workshop to explore zebrafish in cancer research!.Learn more & register here
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RT @MGodinhoFerr: My latest review👇 #zebrafish🐟 surpass #mice as models of telomere-driven aging! With human-like #telomere dynamics🧬 and #….
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RT @StephanHacker2: Great paper by the groups of @BonnetSylvestre and Ewa Snaar-Jagalska in @ACSCentSci. Ruthenium complexes with a caged i….
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Excited to share our latest study! Cyclic ruthenium-peptide prodrugs penetrate the blood-brain barrier and target #glioblastoma, activated by light in orthotopic #zebrafish tumor model. A promising step toward innovative therapies! #CancerResearch .
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RT @BLopesBastos: The main study from my postdoc @MGodinhoFerr is out! #Telomerase isn't required for tumor initiation but its lack drives….
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