Axel Troncossi
@AxelTroncossi
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Ph.D. student within the Leigh group at the University of Manchester.
Manchester, England
Joined June 2022
📢Very excited to announce that our team will be moving to @StAndrewsChem 🏴 later this month. I am so very grateful to @wuerthnergroup 🇩🇪for support over the last 3-years and stoked for our teams future! Check out an updated website at https://t.co/EJwFtX9nvg 🚨🔦💡
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Published in #AngewandteChemieNovit: A kinetically controlled catenane synthesis that does not require persistent strong binding interactions nor the addition of templates by @ProfDaveLeigh & co-workers (@OfficialUoM). Read it here: https://t.co/m6dgxcaVcy
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#AngewandteChemieNovit #OnTheCover Metal-Free Active Template Synthesis of Catenanes (David A. Leigh and co-workers) https://t.co/DugwhBrlSw
@ProfDaveLeigh @OfficialUoM 🔓 https://t.co/5FSOLDCrSg
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#AngewandteChemieNovit David A. Leigh (@ProfDaveLeigh) and co-workers @OfficialUoM report a mechanistically fascinating process for metal-free active template synthesis of [2]catenanes #openaccess. Have a look at the manuscript at: 🔓
onlinelibrary.wiley.com
A new strategy for catenane synthesis is reported that does not require persistent strong binding interactions on the components nor the addition of templates. Metal-free active template synthesis...
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📢 Back-to-back paper from the Leigh Group — now in @J_A_C_S! We directly measure the direction of rotation in a catalysis-driven motor using transient intermediates! https://t.co/7q5lepBmZU Huge thanks to @HuakuiLiu @benjamino_acid @StefanBorsley @ProfDaveLeigh
pubs.acs.org
We report the in situ quantification of directional rotation of a new type of catalysis-driven rotary motor featuring a phenyl carboxylic acid rotor attached to a 7-azaindole-N-oxide stator through a...
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🚨 New paper in Angewandte Chemie Novit! 🚨 Metal-free active template synthesis of catenanes — no strong binding or added templates needed!🧪 Huge thanks to Jiankang, Patrick, @enzoolivieri4, and Prof. @ProfDaveLeigh for the supervision! 👉
onlinelibrary.wiley.com
A new strategy for catenane synthesis is reported that does not require persistent strong binding interactions on the components nor the addition of templates. Metal-free active template synthesis...
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Models are typically used in catalysis-driven motors. In this work, it is not required @J_A_C_S . Huge thanks especially to @ProfDaveLeigh and all our outstanding cooperators @AxelTroncossi @benjamino_acid @StefanBorsley Truly a team effort!
pubs.acs.org
We report the in situ quantification of directional rotation of a new type of catalysis-driven rotary motor featuring a phenyl carboxylic acid rotor attached to a 7-azaindole-N-oxide stator through a...
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Thanks to the organisers for an excellent conference at #ISMSC2025. Thoroughly enjoyed some excellent science, meeting lots of new people and catching up with old friends! Thanks also for the opportunity for a talk to share some of the work we are up to in https://t.co/QNkMteIQyp
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Fully funded PhD opportunity in the design, synthesis and characterisation of artificial molecular machines - 2 years at the University of Manchester; 1-2 years at Peking University. Open only to non-Chinese nationals. If interested, please email me asap.
findaphd.com
PhD Project - (UoM - Peking University) Real-Time Observation of the Dynamics of a Catalysis-Driven Molecular Motor Using a Single-Molecule Junction at The University of Manchester, listed on...
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PhD positions (SNSF) available at the University of Basel (Switzerland🇨🇭)! Join a new research group working on innovative catalytic pathways to produce endergonic/endothermic molecules🔥. For more details: https://t.co/4JALiJcMMY & enzo.olivieri.basel@proton.me
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A Catalysis-Driven Dual Molecular Motor | Journal of the American Chemical Society @OfficialUoM
pubs.acs.org
We report on a head-to-tail dual molecular motor consisting of two (identical) motor units whose pyrrole-2-carboxylic rings are turned in contra-rotary (i.e., disrotatory) fashion about a common...
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An incredible honor to receive award! Thank you so much to the committee, friends, collaborators and @SupraMolChem for recognizing my work. Thrilled to share this achievement with my friend @QingHe_HNU. Look forward to meeting you all in @ISMSC2025
Happy to announce that this year we had so many good candidates that we have 2 Sessler Early Career Researcher Prize winners! Qing He (Hunan U.) and Liang Zhang (ECNU)
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Check out how we made a minuscule motor rotate 24 times in one direction on its own! Huge thanks to all involved, especially @ProfDaveLeigh for making this work possible @ACSPublications @HuakuiLiu @AxelTroncossi @StefanBorsley @benjamino_acid @AlexBetts95
pubs.acs.org
Continuous directionally biased 360° rotation about a covalent single bond was recently realized in the form of a chemically fueled 1-phenylpyrrole 2,2′-dicarboxylic acid rotary molecular motor....
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A really fun project from @ProfDaveLeigh, delivered on the back of @PengLaiWang_96 ’s fantastic efforts, ably assisted by @MartinJ_Power and our collaborators in Strasbourg, Alessandro and @GiusepponeLab, who taught us lots of polymer and materials chemistry. Thanks all!
Out now in Nature ( https://t.co/OeF5SGyEAH)! Very happy to have been a part of this journey. We have integrated a catalysis-driven molecular motor into a polymer gel network to better understand the molecular-level transduction of chemical energy to mechanical force. (1/5)
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Very sad news of the passing of @sirfrasersays, a giant of chemistry for four decades. He pioneered (with J-P Sauvage) the chemistry of the mechanical bond (catenanes & rotaxanes) & recognised that their well defined motions could be useful for molecular machinery... 1/3
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Budding molecular magicians are invited to apply for a 4-year PhD studentship on catalysis-driven molecular machinery (e.g. https://t.co/qWudTDBfUo;
https://t.co/Ndx2Xj9UBO; etc) available in my group, autumn 2025 start: https://t.co/azgS1NNh9z. Position open until filled😃
findaphd.com
PhD Project - [FSE Bicentenary PhD] Catalysis-driven molecular machinery at The University of Manchester, listed on FindAPhD.com
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Out in @NatureChemistry with @GuillaumeDeBo grp. Overhand knot substantially increases scission of polymer under tension (≥2.6× faster); deformation by knot tightening activates otherwise unreactive bonds. Congrats @MinZhangw @FSchaufelberger Lucian &Rob!
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Five years in the making with @benjamino_acid and @ProfDaveLeigh! Out now in @angew_chem, find out how to give chemistry direction with our comprehensive review on Molecular Ratchets: https://t.co/3XP62qCi3r A brief description in the tread below.
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Out now as an Accepted Article in @angew_chem, @StefanBorsley & @benjamino_acid review & discuss how chemistry can be driven inexorably away from equilibrium, rather than relax towards it😃 https://t.co/qWudTDBfUo
onlinelibrary.wiley.com
Ratcheting is the mechanism by which stochastic molecular dynamics, and other random exchange processes in chemistry, can be directionally biased and driven away from equilibrium. In this Review we...
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