Agostinis Lab
@AgostinisLab
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Laboratory of Cell Death Research and Therapy @vib_ccb @KU_Leuven
Joined April 2017
🚨 Where does #lipid peroxidation kick off in #ferroptosis?🔥Excited to reveal #ER-#mitochondria #contactsites as ignition point of the lipid peroxidation cascade!.Huge kudos to our @SassanoLivia &our amazing collaborators making this breakthrough possible.
nature.com
Nature Cell Biology - Sassano et al. identify endoplasmic reticulum–mitochondria contact sites as the intracellular location where phospholipid peroxidation first occurs to promote...
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It is time to leave! Together with a growing number of people and colleagues, we will no longer post or use our X account. You can find us here: @agostinislab.bsky.social. Hope to see you there soon!👋.
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Blazing-fast image creation – using just your voice. Try Grok Imagine.
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Congrats @Franci_Rizz 👏🏻@Julie_bonnereau and all collaborators 🙏 and thanks to our funding agencies @FWOVlaanderen @Stkstichting @vib_ccb.
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🥳 Happy to share our new preprint where we describe the molecular machinery regulating iron transport between lysosomes and mitochondria, how it controls the melanoma drug tolerant persister state and the consequences of its perturbation on ferroptosis.👉
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Absolutely! @CSHANews #Ferroptosis meeting was a huge success! We had a wonderful time in the beautiful Suzhou and discussed exciting science. Thanks to the organisers and to all participants for making this a memorable event! 👏👏👏.
Had an amazing time at the @CSHANews #Ferroptosis meeting in Suzhou China! Amazing science and colleagues. Huge thank you to the organizers! 🤩
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Congratulations to our PhD student Sanket @Sanket4578 and a big thanks to all our collaborators @lab_marine @bstockwell @LambrechtsDlab Francesca Bosisio, Johannes Swimmen 🙏.
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We show that melanoma cell-derived ApoE reshapes lipid architecture and enhances the antioxidant system of the drug-tolerant melanoma cells shielding them from ferroptosis. 2/3.
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🤩Thrilled to share our new study on the autocrine role of melanoma-secreted ApoE in controlling ferroptosis susceptibility across melanoma cell states👇@Sanket4578 et al. 1/3.
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Celebrating the 30th ECDO anniversary 🥳 at the ECDO meeting in Luxembourg with great colleagues @MMittelbrunn, @aksimonlab 🙌🏻 cell death-autophagy- immunology ! #ECDO2024 #celldeath
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Congrats to our Francesca Rizzollo, @Franci_Rizz for winning the 2024 Small World in Motion Competition | Nikon’s Small World:
nikonsmallworld.com
Nikky Corthout - Melanoma cells showing mitochondria and lysosome dynamics
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It was a great pleasure to host Dr. Jessalyn Ubellacker (@HarvardChanSPH) at the CCB. Jessalyin gave a great talk on how melanoma cells metastasizing to the lymph node remodel their ferroptosis dependencies. and we had a wonderful time together in Leuven.
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RT @bstockwell: Looking forward to the CSHA #Ferroptosis #conference in Suzhou Nov 3-8! Abstract deadline has been extended to Sept 20th. H….
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Many congratulations to our postdoc @Julie_bonnereau for winning the @embojournal poster prize at #MRS2024 🥳👏🏻
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💡Another great talk of the last session of #ImmunoOnco24 from Johanna Olweus @JOIweus @UniOslo_Med on the identification of new T cell receptors and how they can be exploited to improve immunotherapy!!!
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Marta Lewandowska from @Mestagtx is giving an excellent talk at #ImmunoOnco24 on the interface of fibroblasts and immune cells interaction!
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🎯In the last session @CoukosGeorge @Ludwig_Cancer at #ImmunoOnco24 gave an enlightening talk on which T cells make it to the tumor in responder and non-responder cancer patients!
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How can we exploit T cells to improve immunotherapy in gliomas? Mind blowing talk from @platten_michael @Plattenlab on #ImmunoOnco24!!!
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Another great talk at #ImmunoOnco24 conference! Amanda Lund @theLundlab @nyulangone is explaining how we can target tumor-associated lymphangiogenesis to modulate metastasis!!!
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💡We just got a deep dive in the T cell dynamics in patients with triple negative breast cancer from Marleen Kok at #ImmunoOnco24 . Very interesting talk on the benefits of immunotherapy in TNBC!
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