ENIGMA-Addiction Consortium
@AddictionEnigma
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The ENIGMA-Addiction working group analyzes data relevant to addiction phenotypes including case-control comparisons across a variety of substances.
Burlington, Vermont
Joined February 2020
joining the working group has never been this easy! if you have data on 🧠and 🧬 that you would like to contribute to become part of the consortium follow the 2-step registration below: #neuroscience #addiction #bigdata #ScienceTwitter #genetics
https://t.co/MWy8PQpg6L
enigmaaddictionconsortium.com
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The #genetics that contribute to quantity of #alcohol consumed only partially overlaps with the genetics that contribute to alcohol use disorder (#addiction). Similar for #cannabis. @PGCgenetics Substance Use Disorder group.
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A #GWAS of a common #genetic vulnerability factor that underlies several substance use disorders (#addictions) identified 19 independent risk loci, many related to #dopaminergic signaling & regulation (@AlexanderHatoum, Nature Mental Health, in press; https://t.co/UyWbtLY1yV) 2/2
medrxiv.org
Genetic liability to substance use disorders can be parsed into loci conferring general and substance-specific addiction risk. We report a multivariate genome-wide association study that disaggrega...
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Substance use disorders (SUDs, #addiction) are defined by problems caused by misuse of a drug, i.e. #alcohol use disorder by problems caused by misuse of alcohol. There is a lot of comorbidity among SUDs. Current #genetic findings reviewed: https://t.co/3H4QSxShLO (1/10)
cambridge.org
Genetics of substance use disorders: a review - Volume 51 Issue 13
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A GWAS of the factors showed some #genes associated with consumption and others with problems. https://t.co/8dO2CoRZdw (4/4)
psychiatryonline.org
Objective: Genome-wide association studies (GWASs) of the Alcohol Use Disorders Identification Test (AUDIT), a 10-item screen for alcohol use disorder (AUD), have elucidated novel loci for alcohol...
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Job alert!! 📢🚨 We are looking for postdoc to join us. Candidate must have completed doctorate training in a neuroscience-related discipline. Experience with MRI and genetics desirable. More info and contact details in the link below 👇 https://t.co/X1yFmrJZI7
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for those who have missed it here's the latest ENIGMA-Addiction video call hosted on March 23rd – special focus on polygenic risk scores 🧬 and fMRI🧠projects! #Addiction #neurotwitter #genetics @enigmabrains
https://t.co/g6d8Jp92R0
enigmaaddictionconsortium.com
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You are invited to join @ENIGMA_ACRI consortium to do mega analysis for biomarker development with fMRI drug cue reactivity with over 2000 subjects/imaging so far! @AddictionEnigma @enigmabrains @AZilverstand More details in the video: https://t.co/CtdME76ELf
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Our latest contribution is now available! 👏📢 Alcohol dependence in young adults and problematic drinking in adolescents is related to differences in brain structural covariance patterns (1/5) #NeuroTwitter #neuroscience #MRI #addiction
https://t.co/CkHkfGzRNU
onlinelibrary.wiley.com
Background and aims Graph theoretic analysis of structural covariance networks (SCN) provides an assessment of brain organization that has not yet been applied to alcohol dependence (AD). We estima...
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Our #ENIGMA #Addiction #Cue_Reactivity Initiative (ENIGMA-ACRI) consensus paper, led by @EkhtiariHamed and @AZilverstand, is OUT in Nature Protocols! @NatureProtocols @nresearchnews
https://t.co/xGwX9mx4lD Congratulations to @enigmabrains, @AddictionEnigma, and the 60 authors!
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And... IT'S A WRAP! ENIGMA's 2021 Year In Review, and what a year! Take a video tour of ENIGMA's global neuroscience projects, highlighting this year's new discoveries in over 30 brain disorders, by scientists in 45+ countries! https://t.co/wsgImjFo8Z PDF https://t.co/7rOPm5UZ7c
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Our latest work led by @racharabin on gender-specific associations with cocaine use on grey matter volume is out!!! #cocaine #addiction #mri this work was part of a @OHBM special issue celebrating the @enigmabrains 10-year anniversary 🔟🎉🧠🎂 https://t.co/MDixjQvOXA
onlinelibrary.wiley.com
Given the variability of gray matter volume (GMV) in select brain areas between men and women, we used voxel-based morphometry data derived from the ENIGMA Addiction Consortium to investigate...
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Human Brain Mapping Special Issue "ENIGMA: The 1st 10 Years" is OUT! 32 papers, global brain studies: https://t.co/kxlzckOJga Kudos to 2000+ scientists making this possible, +editors @PKochunov @njahanshad @lianne_schmaal @AndersonWinkler Jess Turner Gary Egan Sophia Thomopoulos!
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NEW LAB COLLABORATIVE PAPER OUT Brain structural covariance network differences in adults with alcohol dependence and heavy drinking adolescents #addiction #alcoholawareness #ImagenesQueHablan @URNeuroscience #URochesterResearch @AddictionEnigma @IsamNig
https://t.co/BUu1lPFhwS
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New publication in the group!! WM differences in individuals with dependence on stimulants using data from 11 international sites. Thanks to all our members for making this work possible!! 🙏🥳
our latest work w/@AddictionEnigma is out!! 📢🧠we explored WM differences in a multi-site sample of ~800 individuals with dependence on #cocaine, #methamphetamine and #nicotine and used #MachineLearning to derive brain-based classifications using #DTI
https://t.co/Z48O7gLSIB
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So excited about all the fascinating projects and findings presented in the @AddictionEnigma members meeting today! 🧠Sex differences in neuroanatomy of SUD (@lorenzvnt @HBMRC_ACU), cerebellar volume & SUD (@egarzav), structural covariates of abstinence (@Leon_Fonville) and more!
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Want to join us in the next one?👇👇 https://t.co/MWy8PQpg6L
enigmaaddictionconsortium.com
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better late than never – here is the latest ENIGMA-Addiction teleconference held on June '21 where we discussed polygenic risk scores and new MRI modalities available soon in the group (DTI, rs-fMRI) #addiction #neuroscience
https://t.co/U28fMaVq47
enigmaaddictionconsortium.com
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Do you have #neuroimaging or #genetic data to contribute for secondary analyses? You could become a member of @AddictionEnigma, an international working group of @enigmabrains that collects data relevant to #addiction phenotypes across substances. See flyer for further info👇
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**New paper on @JAMAPsych** Cannabis use associated with accelerated cortical thinning from 14 to 19 years of age predominantly in prefrontal regions #development #brain #neuroscience Read the paper and hear the interview below: https://t.co/ATP6YW3iMp
jamanetwork.com
This cohort study examines the degree to which magnetic resonance imaging–assessed cerebral cortical thickness development is associated with cannabis use in a longitudinal sample of adolescents.
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