Ondrej Stepanek - Lab of Adaptive Immunity
@AdaptiveImmuni2
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Lab of Adaptive Immunity at the Institute of Molecular Genetics of the ASCR.
Prague, Czech Republic
Joined August 2018
RT @HuranovaMartina: Check out our fresh review on converging mechanisms controlling #cilia dynamics during #cellcycle and #signaling. With….
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RT @HuranovaMartina: Happy to present our story on how #actin and #CDC42 regulate #ectocytosis and #ciliaryvesicle shedding in #BardetBiedl….
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NOD mice are a valuable model of spontaneous type 1 diabetes. Gluten-free diet (GFD) reduces the T1D incidence in NOD mice. Here, we observed that GFD induces small changes in multiple T-cell subsets incl. Tregs, NKT, gdT cells in NOD mice.
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RT @imgprague: 💗Join Eva in the Laboratory of @AdaptiveImmuni2 .Learn more about our PhD projects 👉Join us, we are….
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We have one open PhD student position in the lab this year.
👾Immunology runs the world, be part of it! Apply at the Laboratory of @AdaptiveImmuni2 . Learn more about the PhD project 👉Join us, we are waiting for you!.Your future starts now!.#phd #phdstudent #science #openpositions #phdcommunity #prague
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Thank you for this official update. Our project ActSwiftly started on January 1, 2025. We are working hard to understand T-cell fate choices in adaptive immune responses.
The initial results of the 2023 ERC grant competitions were published in 2023 and early 2024. Meanwhile, funding has become available for researchers on the reserve list!. Check the updated and final lists of researchers selected for funding 👉
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Consequences of the Open Access religion.
Researchers paid $8.968 billion for their findings to be freely accessible. 🧵1/10
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RT @imgprague: 🧠Is your brain ready for PhD?.Learn more about our projects 👉Join us, we are waiting for you!.Your f….
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Indeed. @msmtcr.@zenisek_m.
If I will kill myself, it will be because of unbearable depression from the Czech bureaucracy diminishing & crippling my ability to do science efficiently & competitively. There's so much crap coming from people who claim scientist's time that it becomes a major limiting factor.
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RT @vercanie: Happy to share our newest preprint on #tcells in type 1 #diabetes 👩🔬. Thanks for the excellent collaboration @AdaptiveImmuni….
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Kromě toho, že relativní rozpočet na vědu klesá, tak z toho malého rozpočtu se často musí platit nové výmysly (data management plans, open access publishing), takže reálné peníze na vědu klesají ještě více.
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This work was spearheaded by @vercanie with a great help of other authors. The study could not be carried out without the excellent collaboration with @NeumanVit Zdenek Sumnik, and Martin Modrak from @FnMotol @2LFUK.
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Happy to share our extensive single T-cell transcriptomic analysis of newly diagnosed T1D children (+1y post). Surprisingly, T-cells, incl. Tregs, were biased towards naive/stem phenotypes. Retrospectively, we saw it in previously published data as well.
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RT @Vedazije: Sněm @Akademie_ved_CR : podíl státních peněz na vědu ve vztahu k HDP klesne o pětinu vůči stavu z roku 2020 .
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Congratulations to @tomas_pluskal! He is the very first @EMBO YIP from Czechia. This is phenomenal. He succeeded where numerous of us have failed—in convincing EMBO that there might be scientific talents worth supporting even here.
27 life scientists have been selected as the newest members of the EMBO Young Investigator Programme. Congratulations and welcome!.Read more:.
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This is great. Congratulations to all!.
Czechia scored big in @ERC_Research #CoG competition. 10 grants! I am more happy than if would get one myself😍 This is first about the #excellence of the people writing & defending the grants. Their success was facilitated by #ZdenekStrakos #ERCExpertGroup. Change is possible!
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Of course, many thanks and congrats to ALL authors.
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Our third and last paper at @emboreports this year identifies the role of intraciliary CDC42 in ciliary actin polymerization and cilia ectocytosis in cells with defective BBSome (Bardet-Biedl Syndrome conditions). Congrats to @avishekprasai Olha Ivashchenko and @HuranovaMartina.
Finally online 🥳great work of @avishekprasai and Olha Ivashchenko and @AdaptiveImmuni2 @imgprague and thank to the @emboreports for great effort and help to make our findings even better 💃
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Povinný "Data management plan" samozřejmě je hlavně další byrokracie a zátěž. Dalo by se říct šikana. Přínosy pro komunitu jsou pochybné. A aby mi někdo něco nařizoval s tím, že je to vlastně pro moje dobro, na to si přijdu už příliš plnoletý.
📂📊 Nakládání s daty je individuální, v každém oboru to půjde jinak, ale vždycky to.musí dávat smysl, shodují se data stewardi Tereza Motalová a Martin Schätz. Péče o data se teď totiž stává nejen trendem, ale hlavně nutností. 🔗
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