Zach Wallace
@zach_wallace_md
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Rheumatologist at MGH and an Amgen employee. My opinions are my own and do not represent Amgen’s position.
Boston, MA
Joined February 2019
NEW RESEARCH—In a retrospective cohort study, frailty—an approximation of biological age—was a risk factor for severe infection in older adults with ANCA-associated #vasculitis
https://t.co/TKNRzHswDv
@SattuiSEMD @zach_wallace_md
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IgG4-related disease Nearly any organ can be affected ▶️Salivary glands ▶️Lacrimal glands ▶️Orbit ▶️Pancreatobiliary system ▶️Lung ▶️Kidney ▶️Retroperitoneum 👉🏽 https://t.co/758F5iuYwT via @RheumJnl
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Major thanks to everyone who contributed to this team effort and @ARD_BMJ for sharing our work. More to come on the role of complement in IgG4-related disease! @zach_wallace_md @alhkim @MGHrheumatology @MGH_ClinEpi 7/7
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Call for applications for the Phil Robinson Global Scholars Program at #ACR24. Must be an early career #rheum/trainee, #rheum professional/trainee, or patient advocate outside of the U.S. & Canada to apply. Deadline June 28. Learn more → https://t.co/cCpUiBEqBz
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📣 #Uplizna met all endpoints for treatment of IgG4-RD in a placebo-controlled trial, @Amgen announced “For the first time, we know that there is an effective therapy to treat patients living with IgG4-RD,” Dr. Zachary Wallace told us Find out more ⬇️ https://t.co/wL25s9VvUc
healio.com
The monoclonal antibody Uplizna met key endpoints in a phase 3 trial for the treatment of IgG4-related disease, marking the first time a placebo-controlled study has shown benefit in the condition,...
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With @Amgen announcing the positive results for the Phase 3 Registrational Trial evaluating Uplizna® (inebilizumab) for treatment of IgG4-related disease, today is a monumental day for the IgG4-RD community. Learn more: https://t.co/MKhuyNtehv
#IgG4RD #ClinicalTrials
igg4ward.org
We now have confirmation through the MITIGATE trial that the treatment approach of B cell depletion in IgG4-RD is effective.
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Inebilizumab hit its primary and key secondary endpoints for #IgG4RD. Huge moment for the IgG4-RD community! Looking forward to full results. https://t.co/eUKXj7ZDpB..
wwwext.amgen.com
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It is #NationalGoutAwarenessDay. #Gout is form of #arthritis that causes severe pain, swelling, redness, & tenderness in joints. Here are some of our teams studies and findings on this #inflammatory disease.
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Pleased to have the chance to write this with @SattuiSEMD.
Patient-reported outcomes in ANCA-associated vasculitis: are the answers in front of our noses? Editorial on the below study now online in AC&R https://t.co/ItUhNOzTsV
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In recognition of Mental Health Awareness Month, we're exploring different rare disease perspectives, including that of Damon Brooks. Damon, a Person of Color living with IgG4-RD, shares his experience navigating IgG4-RD, & the advice he’d give to others.
igg4ward.org
Being diagnosed with a rare disease is challenging, to say the least. Being diagnosed with a rare disease as a Person of Color can create additional
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#MassGeneral physician @zach_wallace_md was quoted in @Medscape's article on research which found that patients with granulomatosis with polyangiitis who scored high on a sinonasal symptom test are nearly three times as likely to relapse.
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A wonderful piece written by a wonderful person @KDAO2011, thank you! This story hits home as it mirrors my own experiences. Karoshi - {Japanese 過労死: Death by Being Overworked} | RheumNow
rheumnow.com
Over the last few decades, Japanese workers were collapsing dead at their desks or committing suicide due to the high stress stemming from their jobs; Japan coined this phenomenon, “Karoshi.” In...
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Many people with rheumatic disease have higher risk for long COVID. However, that risk has significantly decreased since the beginning of the pandemic, according to a new #NIAMSfunded study. Read the #OpenAccess paper via @jrheum: https://t.co/0XFEvfeMBK
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Established to honor a founding member of @rheum_covid, colleague, friend, & leader in #rheum, the Phil Robinson Global Scholars Program provides scholarships to register for, travel to, & attend #ACR24 in Washington, D.C. Must be an early career #rheum/trainee, #rheum
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"Deliberate efforts to address the cardiovascular risk in patients with #gout are likely to be required to reduce mortality.” Could SGLT2 inhibitors help to treat gout? A review from @MonganInstitute researchers considers the evidence: https://t.co/7JWnmp37XL
hcplive.com
A new review considers how SGLT2 inhibitors like dapagliflozin and empagliflozin have been shown to clinically improve gout while reducing its cardiometabolic and renal comorbidities.
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A great team effort with @GuyKatzMD @YhernandezMD and @mbake013 to provide a perspective that we hope will help clinicians managing #igg4rd @IgG4RD
Thirdly, a brilliant overview of IgG4-related disease by @zach_wallace_md, @GuyKatzMD, @YhernandezMD & @mbake013 So much practical information here, including pathogenesis, pitfalls of diagnosis, and approach to remission✨👇 https://t.co/wB0yriEQkd
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Thirdly, a brilliant overview of IgG4-related disease by @zach_wallace_md, @GuyKatzMD, @YhernandezMD & @mbake013 So much practical information here, including pathogenesis, pitfalls of diagnosis, and approach to remission✨👇 https://t.co/wB0yriEQkd
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Register now for the MGH Comprehensive Large Vessel #Vasculitis course 9/6/24 w optional #ultrasound workshop ✅️ https://t.co/CpoCFqKOIF
#rheumatology #medtwitter #meded @zach_wallace_md #sebastianunizonymd @markmatzamd @minnakohlermd
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Remember Evusheld? Appears that sipavibart (generic name for AZD3152, brand name TBD) should come out soon (w/i a month)! Chatter on the street is a possible EUA Friday. Cost hopefully won’t be an issue. Any other barriers to consider? @LCalabreseDO @jeffsparks @zach_wallace_md
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Accelerate your research career at the Mongan Institute! The 8-month Health Care Data & Delivery Science Certificate Program will help you get the skills and knowledge you need to improve health care quality, access, value, and equity. Apply today! https://t.co/VU08nxohuQ
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