Shirley Weiss
@weiss_shirley1
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PhD, Research and development scientist @Collplant
Israel
Joined January 2018
It was a pleasure to be a part of this awesome work, @JManoim!.
My first first-author paper ( is now a real thing at @CurrentBiology! YAY!!!🥳 . Thanks to my super-supervisor @MosheParnas, Toshihide Hige, and the co-authors @dr3wd and @weiss_shirley1. @TAUMedFaculty @Tel_Aviv_Uni @TelAvivUni @UNC_CBP.
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RT @LironRozenkrant: הטוויט הראשון שלי בעברית! :) . המעבדה שלי ( מגייסת למשרת מנהל/ת מעבדה (במעבדה בצפת), וכן אנחנו….
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RT @MosheParnas: Check out our latest preprint led by @JManoim in collaboration with the Hige lab. We show that lateral KC axonal modulati….
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Thank you @medicineino for taking an interest in our work, and for this thoughtful commentary. With @ClaireClamon @DrOrmerod, @JManoim, @MosheParnas.and @JTroyLittleton.
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RT @lab_oren: Check out or new study. Basically - neurons need to silence their activity before pruning. "Use it, or lose it"!. Silencing….
biorxiv.org
Postnatal refinement of neuronal connectivity shapes the mature nervous system. Pruning of exuberant connections involves both cell autonomous and non-cell autonomous mechanisms, such as neuronal...
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RT @koslofflab: As in almost every Nobel prize, there are scientists who made seminar contributions to the field but were not awarded the p….
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RT @masha_niv: פוסטדוקית ישראלית בחו"ל - כל הכבוד לך ולמשפחתך, זה לא קל! להתייעץ במהלך הפוסט, לקבל עידוד ואולי לשפר את סיכויי החזרה למשרה א….
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@GLIA_Journal @MIT_Picower @TAUMedFaculty @ClaireClamon @JManoim @DrOrmerod @MosheParnas @JTroyLittleton Left on the floor of the editing room… The GIF shows a single perineurial cell at the VNC. The robust and Ca2+ activity is visible using a GCaMP6 variant that is tethered to the outer surface of the ER. So much is happening there. Can’t wait to find out what it does.
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We also found that Ca2+ waves originate from the ER and are SOCE, Ryanodine receptor and Gap junction dependent. Genetic interference of these components leads to severe stimuli-induced seizures, supporting the physiological relevance of these Ca2+ waves to brain excitability.
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By performing detailed Ca2+ imaging studies, we show that perineurial cells exhibit robust, complex and dynamic Ca2+ activity that significantly differs between perineurial cells that occupy different brain regions.
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@GLIA_Journal @MIT_Picower @TAUMedFaculty @ClaireClamon @JManoim @DrOrmerod @MosheParnas @JTroyLittleton Using an in vivo RNAi screening in Drosophila, we searched for glial pathways that are crucial for the maintenance of normal brain excitability. We found that perineurial knockdown of dStim, acting in the Store-Operated Calcium Entry pathway (SOCE) leads to severe seizures.
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Thrilled to share our new publication in @GLIA_Journal. Thanks to all the people that worked with me at both @MIT_Picower and @TAUMedFaculty - @ClaireClamon, @JManoim, @DrOrmerod, @MosheParnas and @JTroyLittleton
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RT @JTroyLittleton: Interested in some of the stuff we do in the lab? Elizabeth and Ellen made a recent introduction video for a department….
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RT @KarinaYaniv: Israeli female postdocs- Are you doing your postdoc abroad? We want to keep in touch! Join us so we can follow your progr….
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RT @Yoav_Livneh: Hey Twitter, some personal/professional good news - our new website is live + we are hiring at all levels! If you're into….
weizmann.ac.il
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RT @cshlmeetings: Last year was a momentous one for us and this #infographic provides a look into our 2020; presenting stats like how many….
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RT @JTroyLittleton: Nicole Aponte Santiago.@NicoleApontePhD 's excellent review on invertebrate tonic and phasic neurons is out: https://t.….
frontiersin.org
Defining neuronal cell types and their associated biophysical and synaptic diversity has become an important goal in neuroscience as a mechanism to create co...
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