Are you graduating this year and ready to start your career in the most meaningful way? This is your chance to get on board. #PhD #CancerResearch ➡️ https://t.co/Ln7xs1zphE

We have open PhD positions! Application is now open. Apply to our and other NKI groups via the NKI PhD program at

🎓 Exciting news for graduation master students: In less than one month the NKI PhD program opens! Join our vibrant research community in Amsterdam. Stay tuned! More info on our website: https://t.co/Ln7xs1zphE #PhD

Immensely honored and happy to receive the ERC Consolidator Grant! Looking forward to image many more single molecules in the coming years.

Looking for a PhD position? Interested in understanding gene regulation using live-cell single-molecule imaging technologies? Apply for the NKI PhD program to join our lab or other @NKI_nl labs. https://t.co/ZyuJE43wsH

We are looking for a colleague! Looking for a junior PI position in a vibrant institute? Apply here:

Looking for a PhD? Want to work at a vibrant institute that fosters excellent training and science? Apply to the NKI program! Many top labs have open positions.

Check out our latest review on how cooperativity influences transcriptional bursting. Kudos to the first author Charis Fountas!

End of the summer and need something to look forward to? Submit your abstract for the EMBL Quantitative Biology to Molecular Mechanisms meeting this November! Deadline is almost here. https://t.co/jwUmgZceE2

Abstract deadline is approaching! Register for #EMBLOmics, stellar lineup of speakers, and over 20 talks selected from abstracts. Submit before Aug 27.

Great meeting with many talks from abstracts, register before Aug 27!

Register for #EMBLOmics to join leaders in genomics, functional proteomics, quantitative imaging, microscopy, and theory in discussing data and models 🧬🙌🏻 👉🏾 Over 20 talks will be selected from abstracts - submit yours by 27 Aug! ➡️  https://t.co/UQLKjxuF0m 📅 19 - 22 Nov 2024

We are looking for 2 PhD candidates to study transcription factor DNA binding kinetics and chromatin structure at the single-molecule level in the Lenstra (NKI, Amsterdam) and van Noort (Leiden University) labs. Deadline Sept1.

Fun to write this Journal Club for @NatRevMCB on the 2011 Larson et al. paper in Science, that transformed my scientific thinking as well as my career.

Join our free webinar with @tinekelenstra as she explores gene regulation dynamics in single cells. Discover how misregulation can lead to diseases like cancer and gain insights into transcriptional processes using cutting-edge imaging techniques https://t.co/PPA1X2Z0sH

NKI researcher @tinekelenstra and her colleagues made an algorithm which allowed them to create incredibly detailed recordings of what happens inside a cell: something similar to a relay race occurs on our DNA ➡️ https://t.co/pkc30bikqj

Onderzoeker @tinekelenstra en collega’s maakten een algoritme waardoor ze met een microscoop absurd gedetailleerd kunnen filmen wat er in cellen gebeurt. Wat blijkt: er is een soort estafette gaande op ons DNA ➡️ https://t.co/lIDyorBDzx

4/4 This work was only possible due to the hard work of Wim Pomp and Jos Meeussen! Thanks again to the reviewers for their constructive comments.

3/4 TF exchange may thus be a mechanism to regulate both burst duration and burst frequency upon changing TF concentrations. Such coupling of burst duration and frequency has previously been observed by @gregorscience in Drosophila development.

2/4 If transcription factor (TF) exchange is required to prolong transcriptional bursts, then reducing TF exchange by reducing TF concentration should shorten bursts. In agreement, reduction of the Gal4 concentration doesn't only reduce burst frequency, but also burst duration.