Jacqueline Tabler
@tablerlab
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Developmental biologist using live imaging to understand how the skull grows around the brain. @mpicbg
Dresden Germany
Joined June 2018
Fundamentally, our work demonstrates that mechanisms driving motion in other physical contexts such as gasses, also extend to dynamics generated at the scale of tissues.
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Our work suggests that the slope of a stiffness gradient, not just the absolute tissue stiffnesses, can tune the rate of morphogenesis in vivo.
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We developed a novel biophysical model that provides a simple framework to understand how feedback between stiffness-induced differentiation and cell motility generates can self-propagating wave that expands at a speed set by the stiffness gradient across the tissue.
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Our main findings:.- We find a novel mechanism to drive collective motion DOWN a stiffness gradient. Therefore, our work demonstrates an entirely new alternate mechanism for stiffness-mediated collective mesenchymal motility in vivo.
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Super excited to share with y'all a new mechanism for collective motility in living tissues which can learn about in our latest preprint.🎉.Check it out!.
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RT @carldmodes: New collaboration with the @tablerlab & @florianjug out on Biorxiv Check out @Diana_Afonso_ & @ally….
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RT @mehran_moazen: Don't forget to register for the 2nd "Advances in Craniosynostosis" conference, next Friday. Gre….
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So good to science with these guys.
#lockdown has slowed time so much I went backwards six years! Zoom lab meeting with postdoc alums @ksedzinski, @tablerlab, and @Asakos01. More, more, morphogenesis! Thanks, guys, for the lovely chat.
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RT @mpicbg: The call for a joint @mpicbg & @PoLDresden @tudresden_de junior research group leader on tissue organization and dynamics is st….
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RT @the_Node: New on the Node: Understanding Birth Defects in the Genomic Age.@ashishdeshwar & @nicoleedwds give an early career perspectiv….
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RT @Honigmann_Lab: Check out our work on how to facilitate optical access to apical and lateral membranes of polarized tissue in 2D and 3D….
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RT @viktri08: Our latest preprint: Self-organised symmetry breaking in zebrafish reveals feedback from morphogenesis to pattern formation b….
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So cute.
This beauty, phyllium philippinicum reached Adult last week, look at those beautiful wings and how they mimic a leaf to such detail. Despite the wings this species can’t fly. The wings lack underwings which are essential for flight.
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A fantastic opportunity for those looking for an interdisciplinary postdoc !.
One more week to apply! Deadline to join the interdisciplinary #ELBE Postdoctoral Fellows Program @csbdresden is 12 September. Work with us at the intersection of computer science, physics, and biology! 💻📚🔬 @mpicbg @tudresden_de #MPIPKS
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Woot woot woot! It works!.
The moment of truth - first explant #CRISPR results with @tablerlab @Diana_Afonso_ @andattardi #EMBOmousegenome
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Excited about this week's experiments. !.
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John Wallingford. The 200-year effort to see the embryo
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