Sepideh Dolatshahi
@sepiddsh
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Assistant Professor of Biomedical Engineering @UVABME, @MedicineUVA, @UVAEngineers,@UVACancerCenter, @UVAimmunology
Charlottesville, VA
Joined February 2015
I found out this morning that my @NIH @NICHD_NIH F31 fellowship to study the biomechanics of uterine fibroids was CANCELLED.
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This Thursday is where it’s at! Please join us for Immunology Research Day!
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Thank you @jitcancer for highlighting my work, lab, and collaborators! @UVABME @MedicineUVA @UVAimmunology @mgbvirginia1 @RemziyeErdogan5 @UVAEngineers @UVACancerCenter
Meet the Author: Dr. Sepideh Dolatshahi (@sepiddsh), Asst. Prof from @UVABME, is co-senior author of “Spatial colocalization and combined survival benefit of natural killer and CD8 T cells despite profound MHC class I loss in non-small cell lung cancer,” published in #JITC! 1/7
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We believe a mechanistic modeling lens paves the path to rational design of vaccines and personalized therapies by providing a framework to quantitatively assess the relative contributions of regulators, kinetic bottlenecks, personal & population-level vulnerabilities. @UVABME
Our review in @NatImmunol is out this week!🤰💜We summarize regulatory mechanisms of vertical antibody transfer and highlight opportunities to integrate experimental & computational methods to design better maternal vaccines to immunize babies. @sepiddsh
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Here’s a deeper dive into #JITC article: “Spatial colocalization & combined survival benefit of NK & CD8 T cells despite profound MHC class I loss in NSCLC” from @sepiddsh @RemziyeErdogan5 @mgbvirginia1 @kategoundry20 at @UVABME @MedicineUVA @UVACancerCenter @UVAEngineers 1/11
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Delighted to announce that our collaborative work led by PhD student Remziye E Wessel @RemziyeErdogan5 is now published in JITC! @mgbvirginia1 @kategoundry20 @UVABME @MedicineUVA @UVACancerCenter @UVAimmunology @UVAEngineers
New #JITC article: Spatial colocalization and combined survival benefit of natural killer and CD8 T cells despite profound MHC class I loss in non-small cell lung cancer https://t.co/oQSN8iLYwd
@sepiddsh @RemziyeErdogan5 @CraigSlingluff
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I am designing an elective course on Systems Immunology and/or ImmunoEngineering. If you teach a similar course, know a colleague who does, or know of good resources, please message me. I would love to connect and learn from your experience! 🤗👩🏫🙏
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Shay Ladd presented an engaging poster on Day 2 of Southeastern Immunology Symposium! Her work is supported by the CSBC cross consortium award. @SascoVirginia @NCIsysbio #SIS2024 @UVABME @UVAimmunology
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Remziye continues to do amazing work toward improving maternal prenatal vaccines! Today, she presented her work on the Day 1 of Southeastern Immunology Symposium! #SIS2024 @RemziyeErdogan5 @UVAimmunology @UVABME
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Iylan Howson’s summer research was on Golgi fragmentation in melanoma cell lines under Shay Ladd’s supervision in my lab, proud of both of them! She won best poster award at the UVA REU poster session & will be presenting her poster at #BMES2024 @NCIsysbio @SascoVirginia @UVABME
Congrats to all for a successful SASCO symposium and @NCIsysbio site visit! https://t.co/VaT3razZhH The Hot Ones career advising panel was a terrific success (thanks to Iylan from @sepiddsh lab and Jen from @kashatuslab for participating).
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Grateful to the Hypothesis Fund for enabling my lab's research, and thrilled to be joining the HF community! @UVABME
@UVAimmunology
@MedicineUVA
✨New Awards Announcement💫 We're thrilled to announce our newest awardees, who will uncover fundamental knowledge spanning maternal-neonatal health, protein science, microbial signaling, & planetary+ocean sciences. https://t.co/SqXxI9Qhju Hear from our #HFScouts in our 🧵:
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Today’s the day!
The Beirne B. Carter Center for Immunology Research is excited to announce the 2024 Carter/Anderson Symposium with keynote speakers Drs. Padmanee Sharma @PamSharmaMDPhD , Tyler Jacks @LabJacks , Ellen Puré @pennvet , and Elizabeth Jaffee @DrLizJaffee Please join us April 29th!
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Spatial analysis reveals combinative role for NK and CD8 T cells in antitumor immunity despite profound MHC class I loss in non-small cell lung cancer @RemziyeErdogan5 @sepiddsh
https://t.co/iKEaQWPrOb
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, and the need to devise and deploy NK-activating strategies which are likely to be key to developing highly efficacious next generation immunotherapies. Read more here: link. @MedicineUVA @UVAEngineers
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…, their relationship to both tumor cells and other immune cells in the TME, and their activation status in MHC-I-disparate tumor regions. Our study highlights the importance of the dual presence of abundant intratumoral NK cells and CD8 T cells for long-term patient survival,
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@UVAimmunology @UVABME We applied a systems immunology approach based on multicolor imaging of the NSCLC tumor microenvironment (spanning whole tumors, tumor sub-regions, and single-cell resolution) to investigate the presence of lymphocytes, ...
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Thrilled to present our lab’s highly collaborative preprint "Spatial analysis reveals a combinative role for natural killer and CD8 T cells in antitumor immunity despite profound MHC I loss in NSCLC" with Brown and Bullock labs https://t.co/gXtzCXY7uP
@RemziyeErdogan5
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We went green! Special thanks to Gabe Hanson for heading the efforts! #UVAGreenLabs @UVABME @RemziyeErdogan5
🧪🔬Congratulations to the Dolatshahi Systems Immunology Lab for becoming Green Lab Certified! Your lab can make a difference, too! Learn more about becoming Green Lab certified⬇️ https://t.co/cHHI46q5gH
#LabsTuesdays #UVAGreenLabs #labsustainability @sepiddsh
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