salaitalab
            
            @salaitalab
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              Research group at Emory University studying living/non-living interfaces. #mechanobiology #nanotechnology #biophysics #immunology #integrins #molecularmachines
              
              Atlanta, GA
            
            
              
              Joined November 2016
            
            
           Last week, Sarah, Rachel, and Maia took the stage at the annual SERMACS conference, where they unveiled some truly exciting breakthroughs from the lab. The team's work is pushing boundaries, and it’s inspiring to see their dedication in action! 
          
                
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             Check it out!! Congrats @YuesongH and coauthors! 
           Here we report the DNA Origami Tension Sensor (DOTS) & measure TCR-pMHC forces in cell-cell junctions! Forces measured using microscopy or flow cytometry! @EmoryChem @YuesongH @salaitalab @EmoryUniversity 
          
                
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             Here we report the DNA Origami Tension Sensor (DOTS) & measure TCR-pMHC forces in cell-cell junctions! Forces measured using microscopy or flow cytometry! @EmoryChem @YuesongH @salaitalab @EmoryUniversity 
          
            
            nature.com
              Nature Nanotechnology - The authors present nanoscale DNA origami tension sensors tethered to lipid membranes and reveal the magnitude, dynamics and driving mechanisms of molecular forces...
            
                
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             It’s an exciting week for the Salaita lab! This past Tuesday, Steven Narum defended his thesis titled "Rational Design of a Modular Endosomal Escape Platform to Improve Cytosolic Delivery of Nucleic Acids." Congratulations, Dr. Narum! The future is bright. 
          
                
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             What a phenomenal award season for the Salaita Lab! Congratulations are in order for: Jhordan Rogers- 2024 Quayle Excellence in Research Award @_SarahAbd - 2024 Quayle Early Innovator Award Joe Mancuso- 2024 Quayle Spectrum Scholar Award We could not be more proud of you! 
          
                
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             Force-Induced Site-Specific Enzymatic Cleavage Probes Reveal That Serial Mechanical Engagement Boosts T Cell Activation | JACS @k_salaita @salaitalab @EmoryUniversity @EmoryChem #Enzymatic #Cleavage #MechanicalEngagement #TCell #Activation
          
          
            
            pubs.acs.org
              The T cell membrane is studded with >104 T cell receptors (TCRs) that are used to scan target cells to identify short peptide fragments associated with viral infection or cancerous mutation. These...
            
                
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             On discoveries in the lab: "What looks very smooth and easy is nothing more than lots of practice and very hard work." We spent #15GoodMinutes with Khalid Salaita (@salaitalab) to learn more about his journey and work. Read the article + watch the video: 
          
                
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             The @salaitalab has been at @EmoryUniversity for 14 years. Hear Khalid Salaita, PhD, talk about his career as a chemist, how he balances research and commercialization, and what advice he'd give to his younger self. 
          
                
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             Congratulations to the very awesome and talented @MaiaVierengel for earning the NSF GRFP! We are so proud of you girl 
          
                
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             Sarah is CRUSHing it -- check out her work in detecting molecular compression forces 🧬💪 
          
                
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             Check out Steven's latest work on nucleic acid therapeutic delivery! Using gold nanoparticle-tethered i-motif DNA, we describe smart antisense oligonucleotide (ASO) release upon endosomal acidification and selective membrane disruption. 🧬 #DELVR
             https://t.co/WTMup3tqkZ 
          
          
                
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             Happy International Day of Women and Girls in Science! To the amazing group of women who contribute to the progress, community, and research in the Salaita Group, we appreciate you and we're so proud to have you on our team! 
          
                
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             Check out DNA mechanocapsules for programmable piconewton responsive drug delivery. Congrats Arventh and team!  https://t.co/UbGl0Gtn4f 
          
          
            
            nature.com
              Nature Communications - The mechanical dysregulation of cells is associated with several diseases and strategies to deliver drugs based on the “mechanical phenotype” of a cell are...
            
                
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             Excited to announce the release of Luona's publication on "turbo-charged" DNA motors in Angewandte Chemie!  https://t.co/J5UZnZyems  These DNA-based micro machines move with record-breaking velocity! 
          
            
            onlinelibrary.wiley.com
              Programmable DNA motors with tunable properties. The 0 % GC is the fastest motor and can detect and stall in the presence of single oligonucleotides.
            
                
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             We had a great time presenting on Wednesday night at the Winship Scientific Symposium! Thank you @WinshipAtEmory for hosting us 🥳 
          
                
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             Yuxin's work developing a novel method to amplify cell traction forces, compatible with a 96-well format is out! 
          
                
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