Dirk the Cancer Fighter
@rushmorealum
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Searching for clues in fight against #MBC. Real life therapy needs to hurry up. #TEQ103 (#ErSO) #CF33 #AOH1996 #MTDH #MYC #MUC1* #OTS2.0 #ERX315 #IL12 #TCR
United States
Joined April 2015
MET-X: “Metasasis is the underlying cause of most solid tumor cancer deaths.MET-X will emphasize detecting & ultimately curing metastasis. Uncovering the fundamental principles of metastasis will form the bedrock of curative therapies” #MBC #bcsm @NIH @VP
fredhutch.org
The Center for Metastasis Research eXcellence (MET-X) is an interdisciplinary and collaborative program at Fred Hutchinson Cancer Center focused on one of the most challenging areas of cancer...
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cool but no Er+ Her2- #MBC in trial?
First MYC Inhibitor Shows Promise in Human Clinical Trial OMO-103, an anti-MYC mini-protein, shows positive safety and anti-tumor activity data in phase I clinical trial. Learn more: https://t.co/IOnnEjDAPj
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BriaCell reports disease control rate of 61% in evaluable Phase 2 advanced #breastcancer patients treated with BriaCell’s Bria-IMT™ regimen – the same formulation being used in BriaCell’s pivotal Phase 3 study. Find details: https://t.co/qLW9cMcVHw $BCTX $BCTXW
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you need an expert on that … @ErikaHamilton9 from the one study: Patients had received a median of 4 prior therapies across all lines… Most patients previously received a CDK/4 inhibitor (87%), fulvestrant (80%), and chemotherapy (76%).
@rushmorealum So if I took Ibrance years ago… possible to take this with either Ibrance or another ck4inhibitor? I think there are studies about inhibitors that may work if you space a few years between them. Anyone know?
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FDA Grants Fast Track Status to Vepdegestrant for ER+/HER2– Metastatic Breast Cancer
onclive.com
Vepdegestrant has received FDA fast track designation for select patients with ER-positive/HER2-negative locally advanced or metastatic breast cancer.
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Your gut feeling on antibiotics, cancer https://t.co/IW5zQO1Z81
science.org
Planned trial will manipulate patients’ microbiomes
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“The City of Hope team has identified human ILC2 cells as a new member of the cell family capable of directly killing all types of cancers, including solid tumors.” Please fast track ILC2 for metastatic breast cancer patients. #WorldCancerDay #MBC #bcsm
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no mention of Er+ Her2- #mbc in @TeamImugene CEO Chong’s presentation at Morgan Healthcare Conference. I’m pretty sure they have Er+ #mbc patients in the ongoing cf-33 trial (oncarlytic virus). I assume Er+ will be in the upcoming OnCARlytics trial (cf-33 w/ cd19). Anyone
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Hollings researchers find Boswellia, an extract of frankincense, shows anti-cancer activity in patients with breast cancer | MUSC Hollings Cancer Center
musc.edu
MUSC Hollings Cancer Center researchers show anti-cancer effects of Boswellia, from same tree that produces frankincense, in small study.
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32 out of 42 patients treated since 2022 remain alive suggesting consistently strong survival benefit. https://t.co/vhg6kpPako $BCTX $BCTXW
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This is.. something. So how to weaponize #AI against #mbc? @RecursionPharma would you please pinpoint 1. a drug to trigger anticipatory UPR in cancer cells.. 2. A molecule to break up the duo MTDH-SND1 3. an MYC inhibitor 4. confirm the best molecule to target miRNA-10b
The future of drug discovery is here. LOWE (LLM-Orchestration Workflow Engine) is a cutting-edge software designed to perform complex #drugdiscovery tasks using a natural language interface. 🎥 Discover what LOWE can do ⬇️ Learn more: https://t.co/jrM1OQPTvn
#JPM24 #TechBio
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anything for Er+ Her2- @cityofhope ??? 4 Breast Cancer Treatment Breakthroughs to Look for in 2024
cityofhope.org
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Is venture philanthropy still a thing? @RNAoncology has something novel for breast cancer. TransCode’s lead therapeutic candidate, TTX-MC138, is a targeted therapy designed to treat cancer patients with metastatic cancer- regardless of type. This could really help a lot of
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