Ravi Lal
@raviglal
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Chemical engineering grad student in the Arnold lab @Caltech
Joined August 2021
I'm excited to share our work evolving an enzyme for highly selective synthesis of azetidines with Dave Miller, Luca Marchetti, and @francesarnold! Now published in @J_A_C_S
pubs.acs.org
We report enantioselective one-carbon ring expansion of aziridines to make azetidines as a new-to-nature activity of engineered “carbene transferase” enzymes. A laboratory-evolved variant of cytoch...
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#Preprint up now on #ChemRxiv. Dave Miller, Luca Marchetti, @francesarnold and my work on converting aziridines to azetidines with an enantioselective [1,2]-Stevens rearrangement using an enzyme! https://t.co/V0DyQueT06
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