Proteinbase
@proteinbase
Followers
563
Following
22
Media
8
Statuses
20
The home of protein design data. An open platform by @adaptyvbio for sharing protein designs, their experimental validation and their design methods.
Joined December 2024
Today we’re launching Proteinbase, a single hub for experimental protein design data. Over 1,000 novel proteins are already live, each with computational predictions, experimental validation, and the method used to design them. Everything comes from one lab under standardized
6
51
191
We just opened a community Slack for Proteinbase! If you want to discuss protein design, get help with your workflow, share cool proteins, or give feedback on what we’re building, you’re welcome to join. Here’s the invite link: https://t.co/KTdNuoFrzD Come say hi 👋
0
5
17
Want to dive deeper? Explore individual proteins, full design methods, and other stats in our Proteinbase collection:
0
0
5
The Best ipSAE Award goes to Nick Boyd for his protein 'noble-swan-clay' with a whopping score of 0.92! We received many questions about how ipSAE is calculated - we'll share the exact methods and the reasoning behind in an email to participants soon https://t.co/UHBC9Eh32B
proteinbase.com
Explore experimental data, evaluations, and structure visualisations for noble-swan-clay on Proteinbase. Also known as design_16
3
1
10
We're hitting new records in terms of interest in protein design: • Over 600 people participated • Over 10'000 proteins were submitted • Over 188 different protein design methods were used When uploading their proteins, participants had the option to declare the design
1
4
17
The protein design competition community vote is now open! This edition, we received over 11,000 proteins from over 600 designers. That's more than 5x increase from our last competition. In other words, there's a lot to explore! How to vote: ➡️ Head to https://t.co/fSqIZhFxlu
3
8
31
We just made an app that walks you through designing a novel protein with AI from scratch. Takes about 5 minutes, requires zero biology knowledge. ➡️ https://t.co/JEJD5sd7A7 The best part: we will actually synthesize 1000 of those protein designs in the lab and test their real
25
168
899
Modal is the best platform for running AI models and we use them extensively for all our compute needs. Thanks a lot to the team there for supporting AI for biology research! Find out how to redeem the credits here:
proteinbase.com
Design a protein capable of neutralizing the Nipah virus, a pathogen with up to 75% mortality rate and high pandemic potential, currently lacking effective treatments.
0
0
2
The Nipah virus protein design competition on Proteinbase is heating up! We're now averaging over 500 proteins submitted per day. Want to take the top spot on the leaderboard? @modal now sponsors $500 in credits for you to run protein design models to participate in the
1
6
27
Check out the leaderboard and submit your sequences here:
proteinbase.com
Design a protein capable of neutralizing the Nipah virus, a pathogen with up to 75% mortality rate and high pandemic potential, currently lacking effective treatments.
0
0
2
As a reminder: For wetlab testing, we're selecting - 600 sequences based on the ipSAE ranking - 200 sequences based on an expert ranking - 200 sequences based on a community vote For expert ranking and community vote more details will follow soon!
2
0
2
We've gotten close to 1000 submissions already and now you can find out which ones rank the highest. We're ranking submissions based on average ipSAE score, computed via Boltz2 (check out the competition FAQ for more details).
1
0
1
The leaderboard for the Nipah virus protein design competition is live! Based on popular demand, we're also extending the submission deadline by 1 week -> now open until Sunday November 30.
5
6
24
Want to see the peptides they designed? All sequences + lab validation data are now available on @proteinbase:
proteinbase.com
24 peptide binder sequences designed against the human neonatal Fc receptor (FcRn) with MOG-DFM
0
4
6
Design a protein capable of neutralizing the Nipah virus, a pathogen with up to 75% mortality rate and high pandemic potential, currently lacking effective treatments.
Submissions for the Nipah virus protein design competition on are open! We've already received well over 100 protein designs in just the last couple days. Leaderboard coming soon 👀 Submission Rules: - Up to 10 proteins per submission. - Each sequence must be max 250 AA. - You
1
3
12
🚨 The Protein Design Competition is back: Bigger, better, and more impactful than ever. This time, the global protein design community will test 1,000 novel protein sequences against one of the deadliest known viruses: 🦠 Nipah.
🌍 The biggest decentralized science experiment of 2025 is starting now! The protein design competition returns: we’re inviting scientists, engineers, and hackers from around the world to help design new proteins capable of neutralizing the Nipah virus, a pathogen with up to 75%
0
8
22
Explore the Cradle collection here:
proteinbase.com
12 EGFR binders designed by Cradle for the Adaptyv 2024 protein design competition, generated through Cradle's zero-shot diversification pipeline.
0
0
0
Great to see more and more companies release data on Proteinbase. For every protein design you can find the computational scores and our experimental wet lab results — all available for free for you to understand what are the best protein design models out there.
1
0
0
New collection drop! @cradlebio just released their competition-winning EGFR binders on Proteinbase. Check out how they optimized the commercial antibody Cetuximab and scored the highest affinities in our 2024 Protein Design Competition.
2
6
11