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Nora Pyenson Profile
Nora Pyenson

@norapyenson

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Post-doc and @LSRFdtn fellow studying microbiomes. i 💖 bacteria

New York, NY
Joined January 2017
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@norapyenson
Nora Pyenson
9 months
Check out the official Phage Names in Table S1, like Escherichia phage MiataMamis, that were inspired by loved ones and colleagues, and will soon be immortalized in the National Library of Medicine. 📜.
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@norapyenson
Nora Pyenson
9 months
I’m lucky to have had lots of help with my big postdoc project and a special thanks to @asanchez_lab, Kevin Foster, @PaulTurnerLab, @SchluterLab, @joshuagoldford, Odera Nweke, and @AsherLeeks.
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@grok
Grok
4 days
Join millions who have switched to Grok.
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@norapyenson
Nora Pyenson
9 months
And lastly, our study highlights how phages can live as social organisms. Just like organisms in the macroscopic world, these tiny bits of life find ways to coexist 🫂. (8/8).
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@norapyenson
Nora Pyenson
9 months
Our work shows how ecological “niches” are almost endlessly divisible. Even under strict laboratory conditions, the E.coli population had heterogeneity that phage species could rely on. (7/8).
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@norapyenson
Nora Pyenson
9 months
This study shifts how we think about phage diversity in nature. Phages don’t just rely on host genotypic diversity for coexistence. They use diversity in host phenotypes—similar to how viruses infect different tissues in a human made of genetically identical cells. (6/8).
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@norapyenson
Nora Pyenson
9 months
The E. coli culture wasn’t really a single resource, it’s more like a buffet 🥗 of different cellular phenotypes. Different phage species preferred slow 🥬 or fast 🍅 growing cells which enabled their coexistence. (5/8).
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@norapyenson
Nora Pyenson
9 months
We mapped how each species interacted with their neighbor and found that most species didn’t love sharing their host population ⚔️. So how did they coexist despite this hostility? (4/8).
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@norapyenson
Nora Pyenson
9 months
Coexistence wasn’t random or short-lived, but was stable even when we tried to drive different species towards extinction 🦖 (ie. negative frequency dependent selection). (3/8).
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@norapyenson
Nora Pyenson
9 months
We grew diverse phage species on a clonal (non-evolving) E. coli population and expected one species to beat out all others. Instead we found the opposite: multiple species coexisted in every single community. (2/8).
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@norapyenson
Nora Pyenson
9 months
We asked: Can different phage species (bacterial viruses) coexist on a shared resource 🍝 (a genetically identical E. coli population)? The answer was overwhelmingly yes. (1/8).
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@norapyenson
Nora Pyenson
9 months
Is it “winner-takes all” when the simplest living things compete? Check out my fresh publication on phage coexistence in Science and a thread below🧵
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science.org
Bacteriophages are the most abundant and phylogenetically diverse biological entities on Earth, yet the ecological mechanisms that sustain this extraordinary diversity remain unclear. In this study,...
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@norapyenson
Nora Pyenson
11 months
RT @alexjmeeske: The final version of our paper on anti-CRISPRs "in disguise" as Cas proteins is out today in Nature! Congrats to Mark, Edi….
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nature.com
Nature - We demonstrate that phages have co-opted cas genes from CRISPR defence systems, which subsequently evolved anti-defence functions.
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@norapyenson
Nora Pyenson
11 months
RT @ItaiYanai: Postdocs: we want to start a NYC "Postdoc Night Science" forum where fellows meet monthly for a drink and fun practicing the….
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docs.google.com
Sign up here for monthly meetings for postdoctoral fellows in the NYC area to practice the creative scientific process. For questions contact Itai Yanai ([email protected])
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@norapyenson
Nora Pyenson
1 year
RT @AsherLeeks: I am absolutely delighted to be joining the University of British Columbia next year as an Assistant Professor @ZoologyUBC.….
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@norapyenson
Nora Pyenson
1 year
So fun to present at the Social Lives of Viruses Conference! Even if I cant fully explain this tongue microbiome image. 😛 Thanks @AsherLeeks and @sociovirology for organizing #socialviruses.
@sociovirology
Sam Díaz-Muñoz (they/them)
1 year
@norapyenson @norapyenson: "I mean, I'm not a tongue expert" #SocialViruses
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@norapyenson
Nora Pyenson
1 year
RT @ViralZone: Revealing the unexpected: can some bacteriophages transiently infect Human cells?. "A New Inovirus from the Human Blood Enc….
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@norapyenson
Nora Pyenson
1 year
RT @StuWest8: Bacteria with more variable lifestyles have more fluid pangenomes. @AnnaEDewar @Hao7Chunhui @lauriebe….
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@norapyenson
Nora Pyenson
1 year
RT @asanchez_lab: Sharing the protocol we're using in the lab to rapidly & easily assemble combinatorial sets of microbial communities + sc….
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biorxiv.org
Constructing combinatorially complete species assemblages is often necessary to dissect the complexity of microbial interactions and to find optimal microbial consortia. At the moment, this is...
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@norapyenson
Nora Pyenson
1 year
RT @JotheBiologist: Does your department do a yearly or semesterly bioethics or research ethics seminar? Has it gotten dry and stale? Maybe….
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