Nirav Shah Profile
Nirav Shah

@niravshahmd

Followers
740
Following
331
Media
15
Statuses
220

Joined November 2017
Don't wanna be here? Send us removal request.
@niravshahmd
Nirav Shah
7 months
Excited to share a publication years in the making, our experience with CAR20.19 T cells in relapsed, refractory Mantle Cell Lymphoma now a. Excellent outcomes from IIT @MCWCancerCenter Thanks to great collaborators @timfenske @MediHumdani and many more! https://t.co/aSLSENN27I
Tweet card summary image
ascopubs.org
PURPOSEMantle cell lymphoma (MCL) is an aggressive B-cell malignancy characterized by t(11;14) and bright CD20 expression. To improve outcomes from single targeted CD19 chimeric antigen receptor...
7
11
58
@MeeraMohanMD
Meera Mohan
11 months
Dr. Fenske @timfenske presenting this important late breaking abstract @niravshahmd @MediHumdani @MCWCancerCenter @ASH_hematology #ASH2024
0
4
19
@calliecoombsmd
calliecoombs
11 months
NX-5948 update in CLL - awesome that they permitted CNS involvement (8%). Tox profile looks good. Enrolled variety of BTK mutants. High ORR and responses may deepen.
0
4
9
@HemOncToday
HemOnc Today
11 months
A rapidly delivered tandem CAR T-cell therapy produced favorable outcomes for patients with relapsed or refractory diffuse large B-cell lymphoma, according to data at #ASH24. Healio spoke with @niravshahmd of @MedicalCollege about the data. #Lymphoma https://t.co/dx62UnE1wz
healio.com
SAN DIEGO β€” A rapidly delivered tandem chimeric antigen receptor T-cell therapy produced favorable outcomes for patients with relapsed or refractory diffuse large B-cell lymphoma, according to...
0
1
9
@lymphomahub
Lymphoma Hub
11 months
CONGRESS | #ASH24 | PRESENTATION Nirav Shah @niravshahmd @mcw_oncology presents interim results from the phase II DALY II USA study. Zamto-cel demonstrated encouraging efficacy, with an ORR of 72.8%, and there were low incidences of CRS and ICANS in patients with R/R DLBCL.
1
7
24
@MediHumdani
Mehdi Hamadani, MD
11 months
CD19.20 dual CAR in third or later line DLBCL being presented by @niravshahmd #ASH24
0
12
54
@niravshahmd
Nirav Shah
11 months
Now two multicenter studies with this construct in Europe (2nd line DLBCL) and US (3rd line DLBCL). Thanks to all the people who helped along the way @MCWCancerCenter @MediHumdani @timfenske @Phari among others. Hope to one day see this product approved for pts across the world!
2
1
20
@niravshahmd
Nirav Shah
11 months
https://t.co/Jz6CAmGNGc Excited to share CAR20.19 multicenter data--a nearly 10 year effort. Developed a Phase 1 trial with this construct in 2016, first patient treated at MCW in 2017. Published Phase 1 with target dose, fresh-in/fresh-out CAR cells in Nature Med in 2020.
2
7
24
@MCWCancerCenter
MCW Cancer Center
1 year
In Saturday's #WordOnMedicine podcast, #MCW's @niravshahmd shares how #cancer investigators recently treated the 100th patient in an ongoing #ClinicalTrial using an in-house manufactured, dual-targeted CAR-T therapy for patients with B-cell malignancies: https://t.co/jvYABJAcct
0
4
8
@timfenske
Tim Fenske
2 years
⁦@niravshahmd⁩ presenting our point of care CD19/20 MCL cohort data. N=17. ORR 100%, 88% CR. Only 2 relapses so far. 12% Gr 3 ICANS. No Gr 3-4 CRS. Proud to be part of this work!
1
10
45
@MediHumdani
Mehdi Hamadani, MD
2 years
If you see an eligible DLBCL patient in CR, does #CART outperform AutoHCT? Only available data by @CIBMTR @mshadman Reminds you to keep an open mind, one size does not fit all πŸ™πŸ™ @ASH_hematology for recognizing our work in Press Release #ASH23
7
41
113
@niravshahmd
Nirav Shah
2 years
There is no worse thing MDs have to do than a peer to peer for drug approval. Endless time wasted
0
0
9
@binaytara
Binaytara
2 years
Amazing, and entertaining, session on Aggressive Lymphomas with @sairah__ahmed (@MDAndersonNews), @niravshahmd (@MedicalCollege), and @DholariaMD & @OlaOluwole4 of @VUMChealth here at #HemeSummit23! Great to see lots of audience participation.
0
1
10
@NitinJainMD
Nitin Jain
2 years
1
8
31
@niravshahmd
Nirav Shah
2 years
Excited to be a co-author on my first (hopefully not last) paper in NEJM evaluating outcomes of Pirtobrutinib in CLL after prior covalent BTKi. Data speak for themselves and will be a new option for patients with R/R CLL!
Tweet card summary image
nejm.org
Patients with chronic lymphocytic leukemia (CLL) or small lymphocytic lymphoma (SLL) have poor outcomes after the failure of covalent Bruton’s tyrosine kinase (BTK) inhibitor treatment, and new the...
1
5
54
@LillyOncMed
Lilly Oncology Medical
2 years
NOW PUBLISHED in @JCO_ASCO: Updated results from the phase I/II BRUIN study, investigating a highly selective, non-covalent (reversible) BTKi in patients w/ covalent BTKi pre-treated #MantleCellLymphoma. #lymsm Read the results here: https://t.co/crFIWCwvId
0
7
35
@VJHemOnc
VJHemOnc
2 years
πŸŽ₯ @niravshahmd of @MedicalCollege discusses the rationale and interim results of a study evaluating split-dose R-CHOP for older patients with advanced-stage #DLBCLπŸ‘‡: https://t.co/Ag1kRu84rk @ASCO #LymSM #HemOnc #ImmunoOnc
0
2
9