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Nick Owens Profile
Nick Owens

@nickdlowens

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Group Leader @UniofExeter studying gene regulatory defects in disease. @wellcometrust Career Development Award.

Exeter
Joined January 2016
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@nickdlowens
Nick Owens
9 months
RT @NicolaFestuccia: Our work establishing the orphan nuclear receptor NR5A2 as an essential regulator of early mouse development is finall….
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@nickdlowens
Nick Owens
10 months
RT @ailsamaccalman1: Incredible few days at the Nanopore Community Meeting. Thank you to @nanopore for inviting me to talk about our work l….
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@nickdlowens
Nick Owens
10 months
RT @EricTopol: Genetic underpinnings of menopause age and connections with cancer risk, new mutations in children and reproductive longevit….
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@nickdlowens
Nick Owens
10 months
RT @doctorveera: ExWAS of age at menopause in ~100k women in the UK Biobank reiterates the important role of DNA damage response pathway in….
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@nickdlowens
Nick Owens
10 months
RT @ExeterMed: New research has found 4 genes with some of the largest known effects on timing of #menopause, providing new insight into li….
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@nickdlowens
Nick Owens
11 months
Position open at #PhD, #postdoc or #researchfellow level. Exciting collab. with @MichaelImbeault at Cambridge, @_DiegoBalboa_ and @OtonkoskiT in Helsinki, together with @DrElisaDeFranco and @athattersley in Exeter. Job: My group:
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@nickdlowens
Nick Owens
11 months
#JobAlert Computational #postdoc or #PhD on #singlecell #genomics understanding primate #GRNs involving KRAB ZNF ZNF808 in pancreas development:. Paper: Job: Applications will be reviewed 07/08/2024 but ad will stay open.
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@nickdlowens
Nick Owens
1 year
RT @flanagan_se: Our follow-up paper establishing non-coding cis-regulatory variants in HK1 cause #congenitalhyperinsulinism with variable….
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@nickdlowens
Nick Owens
1 year
RT @ailsamaccalman1: Thrilled to be speaking at the Nanopore Community meeting in September!.
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@nickdlowens
Nick Owens
1 year
RT @nanopore: Ailsa MacCalman is enhancing our understanding of disease & cell regulatory function. At #nanoporeconf, she'll discuss using….
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@nickdlowens
Nick Owens
2 years
RT @flanagan_se: Super pleased that two of our recent genetic discoveries have made it onto Dr. Veera Rajagopal's "Biggest Stories of 2023"….
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@nickdlowens
Nick Owens
2 years
Still time to apply for our #computational #postdoc studying primate specific ZNF808 in pancreas development using #singlecell #Genomics . Job:.
@nickdlowens
Nick Owens
2 years
Not forgetting we are also recruiting a computational post-doc to analyse single-cell data on our discovery that primate-specific ZNF808 is necessary for pancreas development:. Job: Paper:. 5/.
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@nickdlowens
Nick Owens
2 years
RT @nickdlowens: Not forgetting we are also recruiting a computational post-doc to analyse single-cell data on our discovery that primate-s….
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@nickdlowens
Nick Owens
2 years
RT @UniExeterIDSAI: Two fantastic data science and AI roles are available to work with @nickdlowens @uniofexeterHLS. A great opportunity t….
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@nickdlowens
Nick Owens
2 years
Funds available for cross-disciplinary training. Lab post-docs learn to analyse data, comp post-docs learn how to do stuff in lab. Comp post-docs outside bio should consider applying. See for more details. Come and join us in beautiful Devon!. 6/6
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@nickdlowens
Nick Owens
2 years
Not forgetting we are also recruiting a computational post-doc to analyse single-cell data on our discovery that primate-specific ZNF808 is necessary for pancreas development:. Job: Paper:. 5/.
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@nickdlowens
Nick Owens
2 years
Recruiting multiple positions:.1) Lab post-doc - pancreatic differentiation and gene perturbation:. 2) Computational post-doc - stat models of footprinting and convolutional neural nets. 3) Lab technician .4/.
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@nickdlowens
Nick Owens
2 years
We study regulatory regions through the co-operation of multiple transcription factors. We're using single-molecule footprinting (also known as NOMe-seq, Fiber-seq, SMAC-seq, . ) to probe how TFs bind simultaneously and how they're impacted by regulatory variants. 3/.
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@nickdlowens
Nick Owens
2 years
We are studying regulatory regions in pancreas dev. and function to understand rare and common #diabetes and #hyperinsulinism eg. Noncoding variants disrupt a silencer:. Primate Specific ZNF808 is necessary for pancreas dev:. 2/.
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@nickdlowens
Nick Owens
2 years
Amazing to receive @wellcometrust Career Development Award at @exetermed @uniofexeHLS @Exeter_Diabetes . We're studying the sequence code of regulatory regions in disease using lab and computational tools. Recruiting multiple positions:.. See below:.1/6.
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