Michael
@mrmickme2
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FAFO warrior and martyr.
Here, there and everywhere.
Joined June 2024
@ACEGIK1476 We need to be super vigilante about what seasonal flu A is up to given the amount of H5 floating around.
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A few brave "contrarian" scientists got it right in 2020. The rest got paid by Fauci (NIH) and industry to mislead the public.
New research shows SARS2 reinfection doesn’t “boost” your immunity - it narrows it. Each infection further imprints and restricts your T-cell diversity, making your immune response less adaptable over time. https://t.co/2zikOfVUpJ
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This coupled with the US community cases from last week tells you that transmission is happening under the radar. This was inevitable given the expanding situation in Africa and the its continued evolution.
Netherlands gov.: "On 17 October 2025, an #mpox infection involving the new mpox variant 1b was diagnosed in the Netherlands. It is the first time that this new mpox variant has been confirmed in the Netherlands." no travel history
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So much H5 activity going on all over the place. Seems to intensify with each migratory season. We’ve been pretty lucky up until now given no evidence of P2P capability. Not sure what happens if and when it figures out how to successfully attach to the upper airways of people.
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This is exactly the kind of stuff you’d expect to see when COVID’s epigenetic scars accelerate immune aging, lowering viral surveillance and letting shingles reappear in people far younger than normal.
Doctors in China report a surge in shingles among younger adults, especially those who had COVID-19. Media call it “the undying cancer” of the post-pandemic era. Some speculate links to shingles to vaccines, but no studies confirm any connection. Source: https://t.co/OK3bEWOqBY
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“It is also becoming increasingly clear that deregulated epigenetic processes contribute to the development of severe diseases, including cancer and auto-inflammatory syndromes”. This pretty much underscores most of Covs bad outcomes in a nutshell.
@YouAreLobbyLud Which is summed up pretty nicely in this editorial from 2020 titled: Infection-induced epigenetic changes and their impact on the pathogenesis of diseases. .
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HPAI mixing amongst ducks. Yeah … not good. You’d wanna contain these things quickly.
US - "Indiana State Board of Animal Health (BOAH) announced that a commercial meat duck farm in Elkhart County with a flock size of 3,500 has had a positive test for the virus known as highly pathogenic avian influenza (HPAI)." https://t.co/v3fDckbSni h/t Commonground #H5N1
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The "Wartburg Effect" is SARS hijacking of mitochondria. Every SARS infection enables earlier onset of cancer. This is a direct 1 to 1 causality we can't evidence because everyone eventually would die of cancer. #AirborneAIDS #AirborneCancer #WartburgEffect #WearN95
A NEW review explores how SARS-CoV-2 may influence cancer risk. ➡️ Unlike classical oncogenic viruses, it doesn’t insert viral oncogenes. Instead, its proteins: -Inhibit tumor suppressors -Activate growth, survival & inflammation pathways 👉 Potential role in cancer initiation
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Both Chikungunya and CoV-2 enhance viral spread by optimizing membrane fusion to gain entry in to host cells. As with both viruses, ad we can see now that even small changes in the fusion machinery are driving big evolutionary and epidemiological shifts leading to more spread.
Scientists have long known that a single change in the virus’s envelope protein — from an alanine (A) to a valine (V) at position 226 (hence “E1-A226V”) — can make it better able to replicate and transmit via Aedes albopictus mosquitoes
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Another example of global warming and vector-borne disease working hand in hand. As I’ve noted many times before, many regions of the world are becoming increasingly difficult, if not outright impossible for humans to inhabit.
Cuba - "The health crisis in Matanzas is worsening with chikungunya, while authorities downplay the situation. Families are suffering from a lack of adequate medical care and insufficient resources." https://t.co/Tn5kzPjAUW h/t Pathfinder
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Given current reinfection rates, I expect the average to keep declining. Cov binds readily to ACE2 on endothelial cells lining the blood vessels that lead to the brain.
A new UK Biobank study found COVID survivors aged 50+ had a higher risk of new-onset dementia vs uninfected controls. Among 54,757 participants followed for 24.1 months, prior infection was linked to a 41% increased risk. https://t.co/Y61kVPdUnA
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You can see it in the sequences in places like France where S2 mutations in XFG lineages acquiring fusion enhancing mutes from LF.7 such as S:G946R. More fusion can often cause more aggressive infections.
France - "An increasing number of patients are presenting to hospitals or doctors with suspected #Covid19 infections. While a resurgence of the epidemic is noticeable, experts are not alarmed but are advocating prevention." https://t.co/TtME9bCc3z h/t Pathfinder
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Still think it's probably a chronic spill over but something new and improved will crack soon I'm betting.
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Cov may well already be responding to post-wave immune pressure in the US. Example such as this NYC JN.1.13.1 (collected in recent weeks): RBD S455A + L456F (reversion) + Y508H; S2 I896T, N960S. Wondering if we will be seeing other sequences containing 455A/456F/508H?
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A brief reminder: COVID’s spike fuses our cells into dysfunctional blobs. For us people that means scarred lungs, weaker hearts, damaged vessels, and more chronic illness. What happens at the cellular level through fusion is now showing up as declining health across the planet.
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NB.1.8.1 and XFG recombining was only a matter of time given how many of these lineages are running concurrently. Likely quite a few more of these incoming. Should up the fitness advantage.
A new recombinant XFY is designated. XFY is a recombinant of XFG.5.1 and NB.1.8.1, it is now only detected in USA, in New York, Wisconsin and Coloardo. Due to its complexity most AIs fail to generate a complete and correct evolutionary graph. https://t.co/BgMczD78tr
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This will inevitably bring with it recurring hospital and workplace disruptions, while long-term health impacts reduce productivity, creating a persistent drag on economies and major social inequalities.
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You can pretty much bank on two significant COVID waves per annum, with at least one mini-surge in between. Occasionally, you’ll see a massive surge, as in 2023/24, when a heavily mutated variant comes along. In this sense, it’s now an endemic virus.
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Unleashing a forever coronavirus on the world has a way of making a country pretty unpopular with the rest of the global community.
Countries by favourable view of China, 2025. 🇳🇬 Nigeria: 81% 🇰🇪 Kenya: 74% 🇮🇩 Indonesia: 65% 🇿🇦 South Africa: 57% 🇬🇷 Greece: 56% 🇲🇽 Mexico: 56% 🇧🇷 Brazil: 51% 🇭🇺 Hungary: 51% 🇦🇷 Argentina: 47% 🇮🇹 Italy: 45% 🇬🇧 UK: 39% 🇪🇸 Spain: 37% 🇫🇷 France: 36% 🇵🇱 Poland: 35% 🇨🇦 Canada: 34% 🇮🇱
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This is what happens when the online propaganda convinces ignorant people that it’s the vaccines and not the underlying virus that’s making people ill.
BREAKING: Gunman in Atlanta was targeting CDC headquarters because he believed the COVID vaccine made him sick - CNN
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