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Michael Yu Profile
Michael Yu

@michaelkuyu

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Computational and systems biologist, with a focus on microbial life.

Chicago, IL
Joined August 2013
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@michaelkuyu
Michael Yu
1 year
I'm very excited to share our work (with @emily_fogarty11 and @merenbey ) to identify thousands of plasmids in nature and to characterize their evolution and ecology, now out at @NatureMicrobiol!
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nature.com
Nature Microbiology - A set of computational tools to de novo recognize plasmids in complex environments, like the human gut microbiome, and to organize them into evolutionarily cohesive units.
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@michaelkuyu
Michael Yu
1 year
I'm very thankful for @emily_fogarty11 and @merenbey joining me in this scientific adventure!.
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@grok
Grok
2 days
What do you want to know?.
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@michaelkuyu
Michael Yu
1 year
I started working on this project in 2019, only months into a faculty position at @TTIC_Connect. At the time, I was trying to establish myself in a new domain, and I had a burning curiosity to explore the diversity of the microbial world. Trust your scientific instincts!.
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@michaelkuyu
Michael Yu
1 year
Of course you'll find specific ideas about plasmids, but I am generally proud of this work being a case study on how to develop computational methods to discover fundamental truths about biology. I hope it'll have a lasting impact on the greater field in this way. Enjoy reading!.
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@michaelkuyu
Michael Yu
1 year
Check out @merenbey's very nice explanation of the our results, from new algorithms to new biological principles!
@merenbey
A. Murat Eren (Meren)
1 year
I am happy to report that @michaelkuyu and @emily_fogarty11's work that adds more structure to our desire to understand naturally occurring plasmids is now online at @NatureMicrobiol 🎉.
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@michaelkuyu
Michael Yu
1 year
RT @merenbey: I am very happy to report that the years of work we put into studying the ecology and evolution of a single cryptic human gut….
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@michaelkuyu
Michael Yu
2 years
RT @merenbey: Now @emily_fogarty11's pre-print is officially out (🎉), I'd like to tell you more about one of the most curious things we (or….
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@michaelkuyu
Michael Yu
3 years
RT @stochastician: Most "interdisciplinary" seed funding that I've seen operates on what I'll call the "particle accelerator" model of fund….
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@michaelkuyu
Michael Yu
4 years
RT @MicrobiomeVIF: And here a bit of an answers to the biological questions! . #MVIF
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@michaelkuyu
Michael Yu
4 years
I'm excited to be presenting our discovery of >68,000 plasmids and their evolution/ecology at the February #MVIF. Thanks @MicrobiomeVIF!.
@MicrobiomeVIF
Microbiome Virtual International Forum
4 years
🦠 Program #MVIF #6 !🦠. ⭐️Keynote: @SherlockpHolmes .⭐️Selected talks: @doyouseewhy @ClareLou9 @michaelkuyu .⭐️OA highlights: @Sree_sreeram91 @Matt_Snelson. Looking forward to all this talks! 😎. ⬇️Free registration⬇️. See you there, #microbiome people!
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@michaelkuyu
Michael Yu
4 years
RT @merenbey: I'm very honored to be a recipient of one of the most worthy recognitions I could ever imagine receiving: The #ResearchParasi….
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@michaelkuyu
Michael Yu
4 years
Our new work is out! "The genetic and ecological landscape of plasmids in the human gut", with @emily_fogarty11 & @merenbey. Powered by new machine learning and computational methods, applied on a massive collection of microbial genomes and metagenomes.
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biorxiv.org
Plasmids are mobile genetic elements that often carry key determinants of fitness, yet their diversity in natural systems is poorly understood. Here we trained a machine learning model on reference...
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@michaelkuyu
Michael Yu
4 years
RT @minjinlee11: If the shooter drove to “Young’s Asian Massage” & killed the workers there with zero proof of any illegal business, then h….
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@michaelkuyu
Michael Yu
6 years
RT @maralbasoler: New preprint from the lab 'Frequent birth of de novo genes in the compact yeast genome' we show….
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@michaelkuyu
Michael Yu
7 years
RT @NatureNews: We were blown away by some of your responses to our recent Tweet about poor mental health in postgrads. It's time the issue….
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@michaelkuyu
Michael Yu
12 years
I just backed PENGUEMIC - Word Domination on @Kickstarter http://t.co/GlpI6x6x2M.
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@michaelkuyu
Michael Yu
12 years
Cowabunga! First tweet.
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