Mika Martikainen
@mhmartikainen
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Professor and Chief of Neurology at University of Oulu & Oulu University Hospital, Finland. Mito disease, rare disease, movement disorders
Joined December 2012
In mitochondrial disease, some features are extremely important to take into consideration when treating patients. Liver involvement in POLG disease is one good example. A very useful multi centre study just out:
onlinelibrary.wiley.com
Liver involvement in POLG disease is common and associated with high morbidity and mortality. Detailed, large-scale, systematic studies of liver involvement are lacking. This study aims to describe...
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Brilliant. Transmission of knowledge, hunger to learn and understand, love of science; this is what we should learn from our mentors and should try to pass on
What it's all about. 💜🥹 Prof. Joel Mokyr, winner of the @NobelPrize in Economic Sciences, shares a lovely message from a former student.
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Learn how to apply the updated ILAE #SEIZURE classification in clinical practice. This open access practical guide provides useful tips and many cases and videos to optimize educational output. https://t.co/E0RLEYojlX
#epilepsy @yesILAE @EpiDisorders @FilaResearch @IlaeWeb
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Anti-amyloid therapy moves to 'the home' as the FDA approves subcutaneous maintenance dosing for Alzheimer’s disease. Amyloid refers to abnormal protein fragments that clump together in the brain and are strongly linked to Alzheimer’s disease progression. Anderer and colleagues
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Brain atrophy is common in mito disease, also in patients w/o brain related features like epilepsy, ataxia, or stroke like episodes. Stresses the need to develop neuroprotective therapies. Fantastic work by Nora Mickelsson, just out in J Neurol:Â https://t.co/7zwyDpu3xX
link.springer.com
Journal of Neurology - Primary mitochondrial diseases comprise a group of inherited disorders that frequently affect the central nervous system. Previous studies have reported brain imaging...
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New NHS England Neurology Service specification. âś…FND is one of seven core subspecialties âś…FND services MUST be provided in each specialised neurology centre. This is huge recognition of how common FND is in neurology - and unthinkable 20 yrs ago. 1/ https://t.co/XvGo0NIryA
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To shunt or not to shunt, that is the (NPH) question? The first large randomized trial of shunting for normal pressure hydrocephalus (NPH) just dropped in NEJM, and there was clear benefit for walking, and it favored the group receiving shunts. Spoiler alert: Walking improved,
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Kirjoitin @Laakarilehti siitä miten biologiset lääkkeet aloittavat uuden aikakauden Alzheimerin taudin hoidossa. Edelleen on paljon kysymyksiäkin vastattavaksi. @UniOulu @OYS_sairaala
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Our new open access paper looking at Migraine and FND, two of the commonest conditions in neurological practice. Migraine and functional neurological disorder (FND)—a review of comorbidity and potential overlap. https://t.co/Hctieu9iUL 🧵1/
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If you have not been diagnosing SCA27b, Tony Lang says you are likely missing it. Watch out for episodic ataxia presentations that progress to typical ataxia. Thanks for bringing all of us up to speed today in Aspen. @movedisorder #ataxia @NAF_Ataxia @AtaxiaUK
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RFC1 associated disease is indeed an important & still often un-diagnosed condition; in addition to ataxia, sensory neuropathy and chronic cough are important clinical cues. Interestingly, RFC1 expansions also associated w Parkinsonism
CANVAS related ataxia is about to overtake Friedreich's as the most common autosomal recessive ataxia. You heard it first from Professor Lang today DAY 4 ataxia. @movedisorder @NAF_Ataxia @AtaxiaUK @AtaxiaCentreUCL
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This meta-analysis provides evidence that IV thrombolysis does not offer substantial benefit in patients with minor acute ischemic stroke and is associated with increased risks of symptomatic intracranial hemorrhage and mortality: https://t.co/G1PHpZ16sl
#NeuroTwitter #NeuroX
neurology.org
Background and ObjectivesThe therapeutic efficacy and safety of IV thrombolysis (IVT) for patients with minor strokes remain a subject of significant debate and uncertainty. This meta-analysis aimed...
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Use of Antiseizure Medications Early in Pregnancy and the Risk of Major Malformations in the Newborn https://t.co/MnwKLsvuMj
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đź§ On #WorldBrainDay, let's make preventive #BrainHealth an EU priority! EBC drives brain health through awareness campaigns and initiatives in the brain space such as global, EU & national advocacy efforts, projects & @BrainDays. Learn more: https://t.co/wbJY0ir3jk
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Do night and shift work increase or decrease your risk for later dementia? Spoiler alert: new research just dropped in Brain Communications by King-Robson and colleagues and it flips the script on what we thought we knew about night and shift work relative to later dementia risk.
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@EANeurology @CSABrainHealth @EANSonline50 @FENSorg @Euro_Psychiatry @GAMIAN_Europe @IBROorg @EPNSnews @DLR_PT @AgenceRecherche @TomislavSokol @mhmartikainen The #PublicBrainHealthDay, organised by @EANeurology together with @BrainHealth_org, took place yesterday! #EAN2025 The speakers explored how to raise awareness, promote prevention & address key #BrainHealth issues across all age groups & communities. 🎥 https://t.co/iPxqsyzFcU
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Extremely good discussion! Lot of activity around Europe right now, the crucial importance of healthy brains for our societies is increasingly acknowledged.
@EANeurology @CSABrainHealth @EANSonline50 @FENSorg @Euro_Psychiatry @GAMIAN_Europe @IBROorg @EPNSnews @DLR_PT @AgenceRecherche “Brain health is one of the areas with the biggest potential for #research, but also for #investment” - MEP @TomislavSokol. Live from our 2nd TV Studio Session dedicated to National Brain Strategies & an EU Coordination Plan for the Brain with Prof. Dickson & @mhmartikainen.
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Excited to talk tomorrow at #ean2025 on the Brain Health Network Finland and our brain health strategy in the National brain plans & an EU coordination strategy session. Looking forward to a great neurology meeting in Helsinki! @EU_Brain @SuomenNeuro @UniOulu
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Useful reading for all clinicians that may encounter patients w Guillain Barré syndrome:
nature.com
Nature Reviews Neurology - In this Consensus Statement, Leonhard et al. provide a globally applicable guideline for the diagnosis and management of Guillain–Barré syndrome, including...
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Avoin Aivoterveyspäivä EAN-kongressissa 2025 Helsingissä 🧠➡️Lisätietoja tapahtumasta ja rekisteröitymisestä löydät: https://t.co/2emKgTJoGD
#EAN #EANeurology #BrainHealthMission #BrainHealth #PublicBrainHealthDay #ean2025 #Helsinki
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