Matt Nachtrab
@MattNachtrab
Followers
2,634
Following
186
Media
1,186
Statuses
9,193
Posts are not investment advice. Reposted or liked content does not mean I agree with or support what is written in the content.
Tampa, FL
Joined April 2009
Don't wanna be here?
Send us removal request.
Explore trending content on Musk Viewer
Kendrick
• 686182 Tweets
Rio Grande do Sul
• 271835 Tweets
Madonna
• 183773 Tweets
Nicki
• 107698 Tweets
Ole Miss
• 101365 Tweets
Sony
• 92446 Tweets
DAVI NO PODPAH
• 88694 Tweets
Porto Alegre
• 75203 Tweets
Star Wars
• 71973 Tweets
Hope Hicks
• 59399 Tweets
#David69
• 48549 Tweets
スパコミ
• 41460 Tweets
みどりの日
• 35302 Tweets
Mark Hamill
• 32025 Tweets
Keyshia
• 23454 Tweets
Luton
• 22274 Tweets
#TheAmazingDigitalCircus
• 20774 Tweets
Quintana
• 17567 Tweets
Verstappen
• 17408 Tweets
Getafe
• 12066 Tweets
Lando
• 11538 Tweets
Thiago Silva
• 11379 Tweets
Pomni
• 11175 Tweets
Benedetti
• 10820 Tweets
المعيوف
• 10135 Tweets
Pinned Tweet
For four reasons, I decided to release some of the truth and evidence about Dr. Wang and the investigation that the press refuses to report:
1. The investigation is paused and we are likely go many years with no new information regarding the CUNY investigation of the Dr. Wang…
59
70
253
@Travis_in_Flint
87% of the voters in that district voted for Biden. Second highest % in the whole country. Voters elected district attorneys that ran solely on getting Trump! This is political pursecution. He stands zero chance of a fair trial.
137
611
2K
Marcus Allen, a decorated Marine Veteran and 2019 FBI Charlotte Office Employee of the year, remains on UNPAID disciplinary leave without health benefits for over 2 years for raising simple questions about how the Jan 6 investigation was being portrayed in an email to his FBI…
New Filing: FBI is Breaking the Law in its 2 Years' of Retaliation Against FBI
#Whistleblower
Marcus Allen
Press release:
New complaint to
@JusticeOIG
and OPR:
(full PDF)
🧵1. ...with highlights below.
31
575
1K
89
1K
2K
BREAKING.🚨
@RepMTG
Submits Amazing Proposal for Ukraine Aid Bill to Stop America's 'Sick Business Model'
"America Last. America Last. That's all this is. Every single day, America Last."
Rep. Marjorie Taylor Greene (R-GA) delivered a blistering statement on the House's…
465
3K
9K
87
213
853
@JillFilipovic
It was literally what happened. Jose Ibarra is an illegal alien (as defined by law and he was released on parole). Jose killed Laken after being arrested 3 times (illegally coming in our country, endangering a minor, and shop lifting).
1
37
692
@AyannaPressley
It is literally what the law calls them. The laws call them Illegal Aliens when they come in our country illegal.
6
15
674
@SirBylHolte
The democrat mindset is much more like a cult.
Trump supporters are policy based.
287
24
588
@RealPNavarro
I donated to your defense page you mentioned on Tucker. Be safe. We will be working hard out here trying to ensure a Red Wave.
220
40
580
@LeadingReport
The deletion of a ton of deposition footage is very odd. How could that happen accidentally in a case with an unlimited budget?
15
45
561
@JakeLangJ6
I know you are being treated very unfairly along with many others. At least you are bringing transparency to how unfair our governments investigative, legal, and courts are. Politics has worked its way into something that was designed by our founders to be independent of the…
97
70
521
@Riley_Gaines_
It’s good it was filmed. Depending on the background of what caused this, it should be tried as a hate crime.
18
10
493
@IanJaeger29
That is it :( ? Can we please hold the rest of Republicans responsible for not putting America first? Get involved in your district and elect American first Republicans.
27
59
507
@BehizyTweets
Deeply saddening that
@potus
is weaponizing the DOJ against our citizens that were protesting. CHAZ had 6 deaths from gunshots and ZERO indictments. She touches a table and is arrested.
16
78
389
@Travis_in_Flint
Thank you so much for reporting on this. I did not know who he was. Many other people yelled out. I hope this man is not charged as he is obviously very angry over the wrongful murder of his son.
6
32
367
@JerichoXVI
@BehizyTweets
@BoomerSooner59
It’s like they keep the most scandalous votes in a drawer to only use in case of emergency
11
14
354
@CollinRugg
@FreeDanneskjold
I absolutely do not look at that picture and think he was trying to make a black face. It just looks like he put a bunch on the bottom of his face. The reaction is overdone.
2
8
323
@wendyp4545
@SpeakerJohnson
They act like a government shutdown is bad... we want them to shut it down and fix the spending issue. He has to be willing to do that.
14
33
301
@Travis_in_Flint
You think he will be exonerated? I think it’s rigged against him. It will just cement more of us to fight back against this tyranny
5
34
265
Elisabeth Bik's public reputation as a key scientific integrity expert is dangerous for the scientific community. Like it or not, she is regarded as an expert in the industry. Journalists' have told me they cal her for her opinion. Her complaints, X posts, and pubpeer comments…
142
64
253
@stillgray
That sounds a lot like the palistinians that celebrate October 7th but cry when they talk about a palistinian dies. This is racism against the security guard
9
9
225
@kylenabecker
It won't end unless we all vote Republicans. We obviously have to add ammendments or laws to prevent the abuse. The democrats have broken the best structure of government the world has ever had. We need to rise again in honor of our founders and root out this evil.
14
52
229
@thevivafrei
I am glad he said bloodbath. I don’t want him to filter. Their reaction to this is just like all the other lies. This was so blatant and so fast and so wrong. It will make more people see how untruthful they are.
4
12
208
@Pmgraham86
@elonmusk
Engineered for safety. My model X was t-boned in the driver door by a Range Rover going 50 mph and the driver didn’t have a scratch.
@elonmusk
7
7
195
2 years after Dr. Bredt and Jordan Thomas' Citizen Petition against $SAVA's Phase 3 Alzheimer's drug, Simufilam, the fog starts to lift and I'm more bullish than ever. Here's why:
1. Large phase 3 trials, despite odds, are near full enrollment. Amid false claims, media smearing,…
24
70
192
@BreannaMorello
A just and expeditious Floridan Congress already acted to revoke squatters rights and allow police to remove them. Government can actually work for the citizens.
“House Bill 621 authorizes property owners to request action by the sheriff's office to immediately remove squatters from your home.
The bill passed overwhelmingly in the Florida senate last week.
The sheriff is required to serve the notice and remove unwanted occupants without…
147
1K
9K
11
48
180
@RaheemKassam
She walked around in the capital building for 10 minutes. No violence. No vandilization. She is found guilty of supporting Trump. Blatant political procecution.
12
44
178
I’ve received encouraging news that screening for the Rethink $sava trial has been concluded, and patients already in the screening process will now fully enroll in the study. Clinical sites have reported positive outcomes for Cassava Patients on Simufilam, adding to their…
17
44
159
After Review of 24 Month $sava data released today (3), I estimate RETHINK and REFOCUS will report about 2.44 and 3.35 ADAS-cog points better than placebo with significance. For details read whole post.
Good luck short sellers. I think you are totally screwed. Big positive…
18
55
169
@TMGPolitics
I'll take the little wins and celebrate. There is a LONG way to go to end this political procecution and hold the those accountable for violations of the constitution.
8
19
182
Congratulations to $sava and their patients. They have completed phase 3 enrollment of almost 2000 patients into their pivotal FDA trials. The team accomplished this in the face of the largest clinical trial interference campaign ever seen. Evil did not prevail, and…
3
43
160
$sava Simufilam patient update from Dr Doug. 2 Alzheimer’s patients are showing positive cognition from BASELINE two years later. Absolutely amazing news! As I expected some decline as time went on. Also didn’t expect noticeable decline and recovery during 6 month placebo in CMS
24
54
160
@kylenabecker
Why can’t our government speak this succinctly about difficult topics? This is brilliantly summarized by the guest.
7
3
158
Here is a detailed reply to the
@sabinehazanMD
question (7) of the six uBiome papers status.
**The (X) means there is a link(s) below with backup**
The $400m uBiome fraud indictment (8) covered the SmartJane, SmartGut, and Upgrades (rerunning a scan on existing poop or…
10
51
159
$sava or Cassava Science is testing simufilam in 2 phase 3 trials at about 200 trial sites (primarily in the US but a few dozen outside the US) for the treatment of
#Alzheimers
. Both trials have nearly fully enrolled with over 1900 patients. One trial should complete and read…
18
53
152
The FDA cleared the Clinical Trial Sites for the Open Label Trial of simufilam from $sava $savaw.
I reviewed all of the trial sites listed for the Open Label locations (1). I compared the principal investigators at each site to investigators that had investigations by the FDA…
24
42
154
@SirBylHolte
Is this arrests or indictments? Most liberal cities like NY, are taking arrests that would be felony or violent crimes and dropping the indictment to misdemeanor non violent. So the stats look better despite violent arrests being up.
23
10
145
$sava has reported at 12 months that 63% of 100 patients improved an average of 5.6 points in a 17 site US trial. Despite 2 years of attacks on $sava no journal, institution, or government agency has found they manipulated scientific results in any way.
14
53
138
@CollinRugg
@j6prayingrandma
This is political procecution. Our founders warned of this and created constitution to protect citizens from uneven punishment outsized fines and ruling party from procecuting their political opponents. The total damage to the capital was only $1.5m.
7
24
139
$sava responds to
@cuny
with a very well written letter. Full PDF link below (will add court filings in replies to this tweet)
$sava saw exactly what I saw and have tweeted the last few days. They added some more failures. Then the expressed it much more eloquently and…
11
35
138
Research has shown the “from a clinical perspective, plasma p-tau181 can be regarded as an early biomarker for Alzheimer’s disease”. The same article showed strong correlation to other AD biomarkers (Image 2), so plasma pTau181 results do indicate validity in $sava biomarker p2b…
6
39
138
Just when you think
@adamfeuerstein
at
@statnews
could not get any more ridiculous, he shows us once again that he is either purposeful naive and corrupt or just plain naive to drug trials and how they work. Either way it leaves his latest article containing many statements of…
27
37
133
uBiome and Theranos were actual financial frauds.
@MicrobiomDigest
helped uBiome by publishing 5 papers to add legitimacy to the founders insurance billing scheme for SmartJane and SmartGut. The indicted co-founders were Bik’s co-authors and teammates at uBiome. There was a 6th…
8
38
134
$sava has reported unprecedented results in their phase 2 trials as reported by renowned Alzheimer's trial statistician Suzanne Hendrix ((3) video and slides below) saying “the decline of the mild was substantially less than you would normally expect based on comparison the…
15
40
135
Just heard a report from a family member of someone that completed Phase 3 of $sava simufilam and entered in the extended OLE. The report is he is "doing really really well". I don't know if if rethink or refocus.
12
31
135
I just heard from Dr Doug that the two moderate patients in the $Sava taking simufilam “continue to be stable 3 plus years out from initially entering the phase 2 study.”
So his initial reports were that these patients experienced dramatic reversals of their
#Alzheimers
…
11
28
134
@IanJaeger29
I have lost all faith in our federal government and our legal system. We need republicans to sweep so we can get the laws in place to prevent what democrats are doing to trump, his cabinet members, and supporters. It unconstitutional and morally wrong.
11
31
132
New York Times Reports: CUNY Halts Investigation of $sava Alzheimer's researcher citing questions about the integrity of the process.
I have raised some concerns including the lead investigator organizing meetings with known biased
@MicrobiomDigest
and potentially using her as…
16
31
131
$sava RETHINK-ALZ enrollment is complete with 804 patients enrolled. For the 52 week study, the extra 54 patients increase the odds of approval because it is higher powered. The second trial is 1100 patients and should finish soon. Almost 2k patients in an AD trial by a small…
7
27
131
New board member at $sava was number 3 at the FBI. Given Robert Anderson Jr.’s experience, his decision to join $sava puts the risk of any DOJ charges near 0%. The short campaign against $sava was based on a giant hoax.
14
33
127
Below, you will find a $sava patient update from Dr. Doug last night on the yahoo finance board. I’d like to hear the shorts fine ONE individual not on Simufilam that is better 2.5 years after
#Alzheimers
symptoms were obvious and diagnosed. I’ll save them the time though……
10
36
125
New screening has now stopped in both Phase III trials of $sava simufilam. Congrats to the team!!!! The hard part of recruitment is now complete.
10
25
124
The new slide on $sava November deck regarding competition is outlining a case for simufilam qualification for FastTrack designation. New drugs can qualify for FastTrack Designation if the drug has advantages in safety, effectiveness, diagnosis, toxicity, OR public health over…
9
28
126
@CollinRugg
Ms. Davis was a virgin at the time and Lizzo’s whole team seemed obsessed about it. This stuff is very bad that Lizzo did to this woman.
Here is the lawsuit documents.
7
62
125
uBiome Fraud and Bik's Role
The numbers (x) have links down below as reference to where I got that information.
The indictment of the uBiome cofounders talks in length about how uBiome used a captive (controlled by uBiome) network of healthcare providers that because the tests…
6
29
123
Do you know how Dr. Wang's science works?
He is targeting a cure to
#Alzheimers
by targeting Receptor Associated Proteins (RAPs) to influence receptor behavior vs. direct receptor integration with agonists and antagonists.
Do you know who the man is that started this short…
@MicrobiomDigest
@MattNachtrab
@cpiller
@adamfeuerstein
@QCMFunds
@noMidwestHedgie
@Adrian_H
Perhaps before spending money on magic cures people should learn some basic facts about how science works.
1
1
2
15
38
121
Scientific research misconduct complainants (
@schrag_matthew
@MicrobiomDigest
,
@Thatsregrettab1
, David Bredt,
@geoffrey_pitt
, and
@adrian_h
) and the journalists (
@chris_said
,
@cpiller
,
@damiangarde
,
@Dereklowe
,
@adamfeuerstein
, and
@pubpeer
) that write articles about research…
15
26
122
@TerriBurton
@engineers_feed
That’s exactly why I though B. I don’t pick a couch up from the middle!
2
0
118
I just put in an order to exercise 40,000 $sava warrants. I asked the company if they prefer a shareholder exercise warrants or buy shares on the open market. The company said they would like the capital from the warrant exercise.
My logic in paying more than market price is…
23
22
152
The additional data analysis by Erika Cecon at the poster yesterday gives much more evidence on the remarkable reduction in AB42 binding to a7 caused by low concentrations of simufilam (a grain of salt in a 10k liter tank of water).
The author is an expert on FRET receptor…
5
33
119
$sava submitted their objections to the Magistrates Recommendation to Dismiss the Defamation lawsuit.
The summary is the Magistrate failed to evaluate all of the $sava allegations as fact and verifiable. She was supposed to assume the allegations are true and all inferences…
7
18
115
To
@MicrobiomDigest
and her short crew:
You are missing what has happened in Dr Wang's lab. He has sacrificed his personal life with his family to help cure disease with science. He is the hardest working person I have ever met.
He has commuted into work at 4am every day to…
16
18
115
Scientific Integrity watchdogs frequently target based on political motives. 60% of Researchers that were brave enough to stand up and speak publicly about Covid-19 said their credibility was attacked. 15% or 48 out of 321 surveyed said they received death threats. Researcher…
7
44
114
The informal
@CUNY
illegally leaked report summarizes the 10 month investigation of the team at CUNY into allegatons against $sava collaboratd Dr. Hoau-Yan Wang.
It is NOT the formal citation from CUNY as the Science article FALSELY states. The investigation took 10 months…
25
18
113
2 Patients were diagnosed with
#Alzheimers
disease over 2 years ago have been taking $sava simufilam for over 2 years and still have cognition better than they started…. Thanks to Paul for the Thanksgiving update.
5
26
111
I performed a deep research project into
@MicrobiomDigest
work at uBiome and shared it with many journalists to let them know who they are holding up as the hero of integrity. I gave permission to one of the journalists to share the writeup with Bik. She posted snippets of…
@MicrobiomDigest
Upgrade Scheme in Indictment Promoted by Bik Preprint and uBiome Blog Post
In a blog post dated May 8th 2018 , uBiome discussed the reproducibility of the uBiome tests (1). In the blog post, they backed their process of selling upgrades on the same fecal samples stating “how…
3
15
58
10
30
113
Listen to the way one of the world's most advanced Alzheimer's disease statisticians talks about the $sava simufilam data. Many times she talks about the dropping of positive treatment effects from the OLE. She clearly believes there are positive treatment effects from…
4
24
109
Over 80% of $sava Simufilam patients finishing P3 are electing to enter the open-label extension study.
Anyone have any data on what that is like for the Monoclonal antibody drugs?
60-70% of participants are mild. Bodes well for P3 results.
-New August company deck
1
36
112
Exciting news in Alzheimer's research! $SAVA, known for their drug Simufilam, is making waves with their new research published in Frontiers in Aging. Over 500,000 doses given in P2 and P3 studies and zero drug-related side effects! The latest research study highlights…
3
39
110
Aduhelm was discontinued by $biib today. They said it’s not because of safety or efficacy. My take: It is 100% because of efficacy and safety. Patients and Doctors didn’t want it. The cost, health risk, and benefit profile simply made no sense. $Sava simufilam is the most…
19
29
111
$sava has piled more scientific and clinal trial evidence recently supporting my belief that Simufilam is a disease modifying treatment of Mild
#Alzheiemers
patients. This additional evidence has led me to add ~150k more shares since this chain of events started.
1. Simufilam…
13
28
109
@Chris_Said
I have serious issues with the words "credibly accused of fraud" in the attached tweet. A better description is they are being accused of misconduct by outsiders. These outsiders and journalists skip thorough and fair investigations to unfairly and usually incorrectly publicly…
14
9
109
Here is an update from Dr. Doug to help remind everyone why we fight so hard to clear the FUD on $sava. Nearly 3 years later, 2 patients with
#alzheimersdisease
are still better than the started while on simufilam. This does not happen in AD.
#endalz
6
27
111
Goldman from Standford Medicine published a damning article regarding three Amyloid Beta Antibody drugs as a treatment for
#Alzheimers
. In summary, patients are not signing up to receive the drugs. I saw this coming because practicing neurologists I spoke to say they will not…
10
29
105
Today, Lindsay Burns from the $sava team is showing optimism that Simufilam is a disease modifying AD treatment. All the data has backed that up over time-
Quanterix biomarker data
ADAS-Cog data
Patient testimonies
Low drop out rates
Clinical trial site support
Accelerateing P3…
4
30
107
@cuny
were you aware your lead investigator was actively speaking and replying to short seller
@adrian_h
on twitter? He engaged with
@MicrobiomDigest
on a thread with a short seller of $sava spreading FUD about Hoau not teaching any more. Objective?
25
32
109
$SAVA July Simufilam Trial Update
1502 - Estimated phase 3 enrollment
820k -Doses of Simu Administered with ZERO drug related adverse events
1134 - Patients being dosed on Simu
P3 Completion enrollment estimate
Rethink - Aug
Refocus - Dec
March 2024 ~ 900 Completed P3 Trial
5
24
107
$sava strikes back with a lawsuit filed yesterday. I did not read it yet, but it names DAVID BREDT; GEOFFREY PITT; QUINTESSENTIAL CAPITAL MANAGEMENT LLC; ADRIAN HEILBUT; JESSE BRODKIN; ENEA MILIORIS; and PATRICK MARKEY as defendants.
20
33
106
Science magazine should be reporting on how a small molecule drug from Cassava Sciences bound to a Receptor Associated Protein of α7nAChR and reduced Aβ42 binding by 10.9 pIC50 as measured by FRET in 2023.
Expert Quote "a very elegant, robust, and unambiguous experiment…
6
34
102
$sava named 𝙩𝙤𝙥 𝙗𝙞𝙤𝙩𝙚𝙘𝙝 𝙥𝙞𝙘𝙠 for 2023 in Forbes by Contributor Joe Cotton. I think the risks to potential approval were seriously de-risked by Lecanemab FDA approval and ECOR1 investment. Jan update of P3 enrollment is >800; Forbes said 650
7
28
104
@SabinehazanMD
@MicrobiomDigest
was right in the middle of a $400m fraud. She was the Scientific Editorial director, so her writing likely contributed to the documentation for the insurance fraud. She worked on SmartJane that was mentioned 13 times in the indictment.
6
36
104
Second $sava poster at CTAD 2023. The title says it all
"Simufilam’s primary mechanism of action confirmed by time-resolved FRET"
The experts on using FRET to assess binding strength of receptors ran the test.
Screw
@CUNY
, this is third party evidence of Dr. Wang's work.…
12
27
105
If a biotech company wants to reliably and economically learn if their Alzheimer's drug is safe and most likely has a treatment effect, it is smarter to do a larger open label trial than a small placebo trial. $sava brilliantly went this route for the 200 patient open label…
10
18
105
@CollinRugg
She tries to play the victim, but the lawsuit says otherwise. The culture she pushed on the people that worked for her was sick.
@CollinRugg
Ms. Davis was a virgin at the time and Lizzo’s whole team seemed obsessed about it. This stuff is very bad that Lizzo did to this woman.
Here is the lawsuit documents.
7
62
125
3
19
105
I follow and support research in
#AlzheimersDisease
because my grandfather died with dementia, I am an
#apoe4
homozygote (9x more likely to get AD) and all 3 of my children therefor have one APOE4 gene. My brother runs an AD facility. I want to do what I can to find a cure. $sava
7
12
100
Investigators of Dr. Wang inappropriately excluded Western Blots without Molecular Weight Markers from their analysis set with their arbitrary definition of Original Blots. I ran this by an expert (Not Dr. Wang) in this specific area. Policy 1.24 requested the investigative team…
11
25
103
$SAVA shows disease modifying evidence in CMS.
One would expect a symptom-based treatment to RAPIDLY decline during a withdraw study, but Simufilam patients declined at or slower than historical studies show for patients with similar starting MMSE and the same cohort during…
1
24
99
$SAVA is close to reaching their goal of enrolling 1,750 patients for their P3 Simufilam. With 1,587 participants already enrolled, they’re set to reach full enrollment by September end. Hats off to $SAVA, and a heartfelt thanks to all trial participants.
#Alzheimers
7
22
101
@wendyp4545
Where they are getting trump is on process crimes. Biden cooperated. Hur said that Trump resisted their attempts. Process crimes are caused by DOJ and FBI harassment of trump. It’s ridiculous because Biden actually violated the law. Trump did not, but they justify the…
65
19
103
Probes Reporter reports that Undisclosed SEC investigative activity now appears to be over at $sava and they removed them from their SEC watch list. I bet we hear from the company soon on this.
17
38
99
Great quote from Suzanne on $sava simufilam analysis:
"Again what you see that it's VERY RARE to see improvement in a mild group for 12 months. In fact the averages are actually quite a bit lower than that. And the confidence interval around that group with active simufilam…
4
20
100
Tough couple of days for $sava stock but a closer look reveals a resilient and flourishing trajectory. Every month, Cassava successfully mitigates risks, amping up the likelihood of FDA approval for simufilam. The selling pressure is primarily driven by shorts borrowing and…
9
21
99
Just got some data from a very credible source that has a friend in $sava Refocus.
March 2021 MMSE - 17
Sept 2022 MMSE - 24
He has known this gentleman since 1986. The patient was diagnosed with
#Alzheimers
at 59-60 1.5 years before he entered the trial. He does not know…
12
20
98
$sava was picked by
@7Innovator
for his Sept 1st stock saying “A successful outcome for simufilam could turn Cassava into the best-performing stock of our entire 7investing scorecard. For risk-tolerant investors with nerves of steel, this pre-revenue drug developer clearly has…
3
22
99