Keiran Smalley
@LabSmalley
Followers
1K
Following
2K
Media
151
Statuses
1K
Director of the skin cancer research center at Moffitt. Interested in melanoma: cutaneous, acral, pediatric and uveal. #melanoma #uveal #pediatric 🇺🇦
Tampa, FL
Joined November 2019
Out now in @JAMADerm. Our mutational survey of acral nevi demonstrates that most have BRAF mutations!
jamanetwork.com
This cohort study performs targeted next-generation sequencing on a cohort of acral nevi to determine their mutational spectrum.
11
14
82
RT @PatrickHwuMD: Congrats to @LabSmalley and team on their new @jitcancer paper! A 3-drug #immunotherapy combo may overcome resistance in….
moffitt.org
Triplet therapy targeting TIM-3 shows potential to overcome checkpoint resistance in preclinical melanoma models
0
8
0
The most fun image & video creation tool in the world is here. Try it for free in the Grok App.
0
151
2K
RT @jitcancer: New #JITC article: Identification of anti-TIM-3 based checkpoint inhibitor combinations with activity in immunotherapy refra….
0
5
0
RT @LabElsaFlores: Moffitt Study Uncovers New Mechanism of Immunotherapy Resistance | Moffitt Exciting research fr….
moffitt.org
Cancer-induced nerve injury weakens anti-PD-1 treatment, but novel approaches may overcome it
0
6
0
RT @Inside_PM: Treatment-Resistant Melanoma Model Targeted with Triplet Therapy. Combining PD-1, LAG-3, and TIM-3 inhibitors overcomes #che….
insideprecisionmedicine.com
Combining PD-1, LAG-3, and TIM-3 inhibitors overcomes checkpoint resistance in preclinical melanoma models.
0
2
0
RT @KYTsaiLab: So pleased to see this important work published. Congrats in particular to @moranamit2 for this massive effort detailing how….
nature.com
Nature - Perineural invasion and cancer-induced nerve injury of tumour-associated nerves are associated with poor response to anti-PD-1 therapy, which can be reversed by combining anti-PD-1 therapy...
0
3
0
RT @MelanomaReAlli: Moffitt Study Finds Promising New Combo Therapy for Drug-Resistant #Melanoma. By blocking TIM-3 in addition to PD-1 and….
moffitt.org
Triplet therapy targeting TIM-3 shows potential to overcome checkpoint resistance in preclinical melanoma models
0
3
0
RT @PatCarragher: New study from @LabSmalley published in @jitcancer found that triplet therapy targeting TIM-3 shows potential to overcome….
0
1
0
New paper out! Triplet immune checkpoint immunotherapy can reactivate highly exhausted TIM3+ CD8+ T-cells in melanoma @MoffittNews @jitcancer
jitc.bmj.com
Background A significant percentage of melanomas are refractory to immune checkpoint inhibitor (ICI) monotherapies and combinations. As there are currently no effective second-line therapies availa...
1
4
13
RT @KarrethLab: Congratulations to @NeelJasani who defended his thesis last week and his paper was accepted for publication @CR_AACR. Thank….
0
6
0
RT @ATarhiniMDPhD: Our latest published article in Clinical Cancer Research @CCR_AACR | Evidence of potent #immuneactivation systemically….
0
3
0
RT @lynn_schuchter: Today we honor the 10-year anniversary of Tara Miller’s passing, but the truth is we think of Tara every day. And it’s….
0
3
0
RT @MoffittNews: A new study presented at #SMR24 annual meeting could influence how early-stage melanoma patients are selected for sentinel….
moffitt.org
Utilizing a gene expression test could help surgeons and patients decide whether sentinel node biopsy surgery is the right approach
0
2
0
RT @daniela_oaks: Super mega happy for @PatriciaPossik getting the Chris Marshall Award! Paty has done a lot for the Latin American #melano….
0
4
0
RT @InnaSmalley: Join us for the Melanoma Metastasis session at the @SocietyMelanoma Congress 2024. Fantastic lineup of speakers presenting….
0
1
0
And a final uveal melanoma talk from @AndrewEAplin on mechanisms of dormancy and metastasis. @MRFCureOM @SocietyMelanoma
0
2
10
And next our very own @post_reddy giving an update on new drivers of uveal melanoma liver metastasis. @MRFCureOM @MoffittNews @SocietyMelanoma
0
3
15
2
2
16
Very cool talk on acral melanoma in Brazilian patients from @PatriciaPossik. @MelanomaReAlli @SocietyMelanoma
1
2
18
RT @MelanomaReAlli: Team MRA is excited to be at @SocietyMelanoma in NOLA and already diving into some exciting #melanoma #research! #SMR24….
0
4
0