The term scleroderma often is used to describe 2 separate autoimmune disorders: (1) morphea and (2) systemic sclerosis. This Patient Page describes the symptoms, diagnosis, and treatment of scleroderma.

A woman in her 40s with a medical history of complex regional pain syndrome presented to the dermatology department for evaluation of a pruritic recurrent rash on her right anterior thigh that started 1 month prior. Take the Clinical Challenge:

This case study demonstrates that abrocitinib, a selective JAK1 inhibitor, successfully treated a patient with SAPHO syndrome, showing improvement in symptoms and quality of life.

A woman in her 40s presented to a immunobullous disease clinic with a 30-year history of an intensely pruritic eruption predominantly affecting her legs, forearms, and hands. What is your diagnosis?

Sporotrichosis, a subcutaneous mycosis caused by Sporothrix species, has one of the highest human incidence rates in China globally. This case series reports the incidence of sporotrichosis among 6 restaurant workers in Shandong, China.

Acne keloidalis nuchae (AKN) is a chronic skin condition characterized by inflamed hair follicles that can cause hair loss and substantial scarring. This Patient Page describes the symptoms, diagnosis, and treatment of AKN. @drprince.a

Patients with autoimmune skin diseases experienced better survival outcomes after antineoplastic treatment for cancer.

The combination of linperlisib and chidamide was a safe and potentially effective treatment for relapsed or refractory cutaneous T-cell lymphoma.

In this network meta-analysis, sonelokimab, adalimumab, lutikizumab, and bimekizumab were the most effective treatments for moderate to severe hidradenitis suppurativa.

Standard alphapapillomavirus vaccination was found to reduce actinic keratosis burden in immunocompetent individuals with multiple lesions. #AAD2025 .

Most viewed this week from @JAMADerm: . Dupilumab treatment in atopic dermatitis patients is associated with a 58% higher risk of developing psoriasis compared to other systemic agents.

In cutaneous squamous cell carcinoma (CSCC), the number of risk factors is directly associated with increased risks of recurrence, metastasis, and disease-related death.

Bimekizumab, an IL-17A and IL-17F inhibitor, improved severe, treatment-resistant acne conglobata in two patients, suggesting its potential as an effective treatment option.

This consensus statement established diagnostic criteria for metastatic cutaneous Crohn disease (MCD), which include major and minor clinical and histopathological criteria.

Photodynamic therapy exhibited good tolerability and safety in non-immunocompromised patients with localized cutaneous M marinum infections.

A 6-year-old girl presented to an outpatient clinic with a history of a red plaque on her chest for over 4 years. What is your diagnosis?

Most viewed this week from @JAMADerm: . Dupilumab treatment in atopic dermatitis patients is associated with a 58% higher risk of developing psoriasis compared to other systemic agents.

A man in his late 60s was seen for a new onset of an erythematous eruption on his arms and upper trunk. Read the full case report:

Increased environmental pollutants and temperature extremes are associated with a higher burden of atopic dermatitis.

VISIBLE trial Cohort B: Guselkumab effectively clears scalp psoriasis, improves quality of life, and maintains results through 48 weeks in individuals with diverse skin tones.