Arnold_lab
@lab_arnold
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Mucosal immunology lab @UZH 🔬! Eosinophil fanatics👩🏻🔬👨🏽🔬, exploring their fascinating role at steady state, during inflammation 🦠 and cancer.
Experimental Immunology, UZH
Joined October 2021
Happy to present our data on the transcriptional regulation of eosinophils in cancer at the 2025 Granulocyte Meeting, Shanghai #ThePoweOfMany #Gmeeting2025 @lai9uan
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Wonderful time and great science in Shanghai at the #Gmeeting2025 with an exceptional line-up of speakers!
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Happy to present our new data regarding the transcriptional regulation of eosinophils in the tumor microenvironment #iuis2025 @EosinophilSoc
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Exciting new study from @ArielMunitz and his lab reveals a pathological role for the alarmin TSLP in eosinophilic esophagitis, highlighting it as a potential therapeutic target. It was a pleasure to collaborate on this work! https://t.co/cTWN0hxFz1
onlinelibrary.wiley.com
This study described the expression and function of TSLP and IL-33 in an experimental model of EoE. TSLP and IL-33 were overexpressed in human and experimental EoE. Human and mouse esophageal MCs...
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We had such a great time in #Montpellier at the #IES2025. Big congratulations to our awards receivers: Glenn for the best oral abstract talk and travel grant, @danielcrepaz for best abstract slam and James for travel grant! #eosinophils
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@arnoldlab Isabelle with a great overview of eosinophil T cell interactions in a “state of the art” review 💪🏻 #IES2025 @EosinophilSoc
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wonderful time here in Montpellier: exciting science, great people and lots of eosinophils! #IES2025
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#KSMyeloid25 I am delighted to present our @lab_arnold work at the Keystone Symposia in Hannover. Visit me at the poster session and my #talk in the Granulocytes session today to hear more about neonatal #eosinophil tissue integrity functions and their impact on the microbiota!
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Mark your calendars for 22 January 2025! IES & EMBRN are coming together for a joint webinar on Single Cell Dissection of Human Mast Cells, Basophils and Eosinophils. Register now: https://t.co/EpPV5W9wWK
@KhouryMD @DrMMukherjee @RossanaMelo5
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Read our exciting new story about the #eosinophil - #macrophage axis that controls tumor metastasis in CRC 📕
We are very excited to announce the release of our latest preprint exploring eosinophil dynamics in colorectal cancer (CRC)! 🧬🧫👩🔬 https://t.co/jT473t0qeF Find our key findings in the comments below! #colorectalcancer #eosinophils #spp1macrophages #tumormicroenvironment
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📌 This novel eosinophil-macrophage axis may open new avenues for controlling CRC progression and metastasis.
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📌 Eosinophils suppress peritoneal metastases by modulating the differentiation of pro-tumorigenic SPP1+ TAMs
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📌 Eosinophil activation patterns and transcriptional programs are conserved within tumors in mouse and human CRC
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We are very excited to announce the release of our latest preprint exploring eosinophil dynamics in colorectal cancer (CRC)! 🧬🧫👩🔬 https://t.co/jT473t0qeF Find our key findings in the comments below! #colorectalcancer #eosinophils #spp1macrophages #tumormicroenvironment
biorxiv.org
Eosinophils, traditionally associated with allergic responses, have emerged as critical immune modulators in colorectal cancer (CRC). Here, we reveal that eosinophils actively shape the tumor...
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Our key findings include: 📌 Eosinophil activation patterns and transcriptional programs are conserved within tumors in mouse and human CRC
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Abstract submission is now open for the 13th Biennial Congress—taking place 7–11 July 2025 in Montpellier, France! Submit here: https://t.co/ahm1kIzJj3 Key Deadlines: Abstract Submission: 16 March 2025 Late-Breaking Abstracts: 15 May 2025 Presenter Registration: 1 June 2025
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Join Our Research Team! We study immunological mechanisms of allergic diseases, and how these mechanisms may participate in cancer. See: https://t.co/h09xJQFUYY Or: https://t.co/RBaTcdaOtN MSc, PhD & postdoc positions available. DM or mail me with your CV and cover letter 😊
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Check out our lab's latest paper out in @Nature! Congrats to @cocoborrelli and everybody involved 🎉🥳
How are cell-cell interactions governing successful metastatic colonization in the liver? Have a look at our new paper in @nature that introduces an in vivo proximity screen to functionally test cellular interactions in a high-throughput manner. https://t.co/oWFn3Hfj8M 🧵
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How are cell-cell interactions governing successful metastatic colonization in the liver? Have a look at our new paper in @nature that introduces an in vivo proximity screen to functionally test cellular interactions in a high-throughput manner. https://t.co/oWFn3Hfj8M 🧵
nature.com
Nature - Interactions between plexin B2 on hepatocytes and sempahorins on disseminated tumour cells regulate metastatic seeding in the liver.
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Spatial adaptation of eosinophils and their emerging roles in homeostasis, infection and disease https://t.co/N4UO0RIv4T
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