Dr Kevin Martell
@kevinmartell
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Radiation Oncologist. Views expressed are my own and do not reflect those of my employer.
Canada
Joined July 2009
AI generated pic w 2 bells on the stethoscope or an absolute boss?🧐
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Thanks @DrSpratticus for highlighting AS in IR ds. @RDC13ro has now updated those data by APP4 (absolute percentage pattern 4/5). 15y FFM same for GG1 vs <5% GG2 (around 95%) #ASTRO25
@ChapinMD @HimanshuNagarMD @AmarUKishan 4/n If WW in IR and AM in GG2 are not safe, then what about AS in GG2? Sunnybrook data shows that this still is not very safe with 15 year mets risk of 16% in their historical data published. Note that almost all mets events occur around or beyond 10 years. @DrAndrewLoblaw
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GETUG-14 trial: In localized prostate cancer, adding 4 months of short-term ADT to high-dose RT improved 5-yr DFS (84% vs 76%, HR 0.64) & reduced biochemical + metastatic failures, without ↑toxicity. No OS benefit seen. @OncoAlert @APCCC_Lugano @EUplatinum @DrYukselUrun
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We’re so proud of your vision and leadership Gerard!
Congratulations Dr Gerard Morton on this well deserved recognition- 2025 Henschke Award recipient. We cannot be more proud of our Canadian Brachytherapy leaders @mirakeyes @CanadianBrachy @UofTDRO
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A rockstar radonc @DrAndrewLoblaw once told me it’s always comforting when you find a study that confirms your biases. This gem I’ve been waiting for for a while now… https://t.co/MtvSLK56yG
thelancet.com
To our knowledge, this is the first randomised trial for metachronous PET-detected nodal recurrences comparing two local treatment approaches (MDT and ENRT) in combination with 6 months of androgen...
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My approach to boosting small psma pet positive nodes. Not perfect but seems to be working. https://t.co/xSAOZDsIP4
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Dr Mendez presenting the acute toxicity results of the HOPE trial looking at 25/5 to the whole pelvis plus brachytherapy.
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New FIGO staging taking histology and substantial LVSI into account @KamravaMD @AnnKloppMD @bindhu2102 @AndrewKellerMD #gynsm
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@DrAndrewLoblaw @aleberlin2 @dr_vesi @kevinmartell @DrMarkCorkum ...Even in #Canada? Heart breaking, I must say...
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you're too modest! It's more of a hypothetical ... Not really patient driven.
@kevinmartell @DrAndrewLoblaw @DrSpratticus @lucascmendez @gerard_morton @dr_vesi @kevinmartell thanx for including me. I am humbled but honestly I am not a GU guru at all...there are stellar people around me including u. Just curious to know what is the post-op PSA and was the mets picked up by PSMA or both PSMA and conventional?
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Agree. VERY TEMPTING! The one's I've treated have done very well...
@kevinmartell @DrAndrewLoblaw @DrSpratticus @SouMyajiT_RO @lucascmendez @gerard_morton Sounds like an interesting question for a trial (that of course would likely not be feasible) When discussed @Sunnybrook consensus is to only treat the PSMA avid disease, preferably on trial. The tempting thing is to only use a short course of ADT to see if the patient is cured
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Interesting! My fear is it might be more nuanced if there were several risk factors for local recurrence but no gross disease. As @dr_vesi hinted it's tempting to check if we've cured a patient after SBRT. TBCC considers ARAT and SBRT for these patients. Prostate bed is grey zone
@kevinmartell @DrAndrewLoblaw @DrSpratticus @SouMyajiT_RO @gerard_morton @dr_vesi A negative PSMA-PET or positive disease uptake in the prostatic fossa is the best predictor for ffp in patients receiving salvage RT (check Emmet j Nucl Med 2020) I don’t treat the prostate bed in patients with known mets, independently of being on conventional or PSMA scans.
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Hey twitterverse/GU gurus. Wondering what your thoughts are. Patients with 1)conventionally detected vs 2)PSMA detected met post RP. You're SBRT/SABRing the met ... Do you treat the prostate bed @DrAndrewLoblaw @DrSpratticus @SouMyajiT_RO @lucascmendez @gerard_morton @dr_vesi
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Lolll
@kevinmartell @DrChowdharyMD @DrAndrewLoblaw @Sunnybrook @seanmmcbride @SbrtSean @brettcoxmd @DrSpratticus @DrLesterColl @ChapinMD @drmattmcfarlane In my experience a #radonc doing prostate biopsies would be seen as overstepping scope of practice and alienate urology colleagues. It sounds great but I just don’t see it as realistic. Urologists owning radonc facilities is $omehow more palatable to the urologist.
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Coming to an upcoming issue of #brachyjournal ... HDRBT toxicities across all reported studies is VERY low. LDR makes sense ... Seeds travel ... Posteriorly
@DrAndrewLoblaw @DrSpratticus Higher toxicity with LDR boost in comparison to HDR-BT boost is more evident now considering this and other recent reports (Hoskin trial, RTOG 0321, TROG Radar, etc) would be possible/feasible to limit ASCENDE-SABR BT arm to HDR boost only?
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🤦♂️🤦♂️🤦♂️ https://t.co/gNhKn9xGNW: Southern Alberta churches, residents file court challenge to COVID-19 rules as cases surge. https://t.co/uB0SYE9vVw via @GoogleNews
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Just finished reviewing a series of abstracts for #wcb2021 - online ... Going to be an exciting conference!
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.@heinvanpoppel: "PSA testing was discouraged, because #ProstateCancer diagnosis automatically led to active treatment. We were not able to discriminate between significant and insignificant cancer." "But times have changed!" 👇 #EPAD20
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Is hypofractionated WPRT safe in high-ish risk prostate cancer patients treated with HDR-BT boost? Check out the HOPE-Trial below! To our knowledge, this is the first RCT investigating this question. https://t.co/vpRHvbh4Qs
@kevinmartell @lhscradonc @rad_onc @axarifin
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.@AHS_CancerCare #TomBakerCancerCentre Radiation Oncologists at our start line of the #CARO2020 #CAROVSM2020 @caro_acro_ca Dr. Pamela Catton Memorial Run / Walk for @CROF_FCRO Let’s go!
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