📢 Now accepting applications for the JEM Early Career Travel Award, for grad students & early-career postdocs to participate in a scientific conference! This year, the award will support the attendance of #Cytokines2025 @CytokineSociety! Apply here 👉

.@HYcheng215, @ZhaozhuQ et al. @HopkinsMedicine reveal that the PAC channel negatively regulates phagosome maturation in macrophages. PAC Channel deletion enhances bacterial clearance & immune responses, incl. STING-IFN & inflammasome activation.

RT @KarinaYaniv: Happy to see our work, led by @IvanBassi, out today in @JExpMed! Zebrafish help us find new treatments for a #rare_disease….

.@IvanBassi3, @karinayaniv @yaniv_lab, Greenberger et al. use #zebrafish to help identify new treatments for a severe lymphatic malformation. @WeizmannScience @Ams_Jabali @TelAvivUni @sheba_medical @ERC_Research @ODC_UPenn

🎥 See a short video summary of a study by Chae Won Kim (@EmmaChaewonKim) of the Heung Kyu Lee's lab (@heungkyulee):

🎥 New video summary of a study by Chae Won Kim (@EmmaChaewonKim), Hyun-Jin Kim, Heung Kyu Lee (@heungkyulee) & colleagues () showing that gut dysbiosis from high-salt diet promotes glioma via propionate-mediated TGF-β activation:

Kaiyang Tang, Lijian Wu et al. of the @deng_pan_lab @MedTsinghua report that an in vivo #CRISPR-Cas9 screen reveals that inactivation of Calreticulin (CALR) potentiates CD8⁺ T cell-mediated anti-tumor immunity and overcomes tumor immune evasion.

Kenison and Quintana @harvardmed discuss work by Chatterjee et al. ( demonstrating that disruption of the gut microbiota promotes #neuroinflammation and cognitive decline through the loss of #microbiome-derived metabolites.

📢 Tell your friends and colleagues about JEM’s Early Career Travel Award! ✈️🧳 We're providing support for #gradstudents and early-career #postdocs researchers to attend #Cytokines2025, this November in Seattle! Apply by Sept. 26 👉

Roark, Habib, Shaw, Kwong, Shapiro et al. @columbiamed @pennmedicine @niaidnews infect macaques with chimeric simian-human immunodeficiency viruses to induce broad #HIV-1-neutralizing antibodies targeting the V2 apex site-of-vulnerability. #Virology

JEM's latest #CME activity @MSKCME is now available! ✍️💻 New content📄: “Epitope and HLA specificity of human TCRs against Plasmodium falciparum circumsporozoite protein” by van Dijk et al. ( . Begin the CME here 👉

RT @IFC_UNAM: Conoce más sobre la trayectoria de nuestra investigadora Paula Licona 😊.

RT @ragoninstitute: Congratulations to Ragon Early Independence Fellow @immunoliugy who was spotlighted in the @JExpMed Women in STEM featu….

RT @scrippsresearch: Scripps Research Assistant Professor Alejandra Mendoza (@thepenkpanther) was recently featured in @JExpMed's ‘Women in….

#Lipid #metabolism and #neuroinflammation: What is the link? A new review from Vini Tiwari (@vinitiwari1) & Mikael Simons on the relationship btwn lipid metabolism & #inflammation & how disruptions in this interplay contribute to neurological disorders

Gristick, Bjorkman et al. @Caltech report a new germline-targeting #HIV-1 Env SOSIP trimer, 3nv.2, that binds to bNAb precursors targeting the CD4bs, V3, & V2 epitopes. Immunization expts show 3nv.2 elicits the combined effects of its parent immunogens

Ciliated cell–derived IL-17D restrains allergic #asthma through controlling #monocyte recruitment, say Lei Yuan, Chen Dong et al. #MucosalImmunology #Inflammation #Cilia

RT @Lucie_JExpMed: The first Viewpoint in our 2025 series is up! Huge thank you to contributors Sophia Liu @immunoliugy, Margarida Saraiva,….

RT @niseto: Here's our take on how neutrophils can be a critical link between cancer and cardiovascular disease! "Heart of the matter: Neut….

#Cancer patients display an elevated burden of #CardiovascularDisease. This review from Ambreen, @niseto et al. @TheCrick explores cancer-elicited changes to #neutrophil behaviour and proposes ways in which these may contribute to cardiovascular pathology.

RT @Gaia_JExpMed: Don't miss the 2025 #womeninSTEM becoming independent" series @JExpMed!.