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Jan Domanski Profile
Jan Domanski

@jandom_random

Followers
299
Following
6K
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112
Statuses
738

Forbes 30U30, ex-CTO @Labstep, ex @DEShawResearch, ex @amazon. Software and drug-discovery at @charmtherapeutx

London, England
Joined March 2016
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@jandom_random
Jan Domanski
4 months
What a joke…
@andreasklinger
Andreas Klinger 🦾
4 months
People think i am making this up This is who got interviewed by them. 85% legacy stuff and their lobby arms
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@venturetwins
Justine Moore
5 months
When the vibe coding is over and it's time for vibe debugging
@venturetwins
Justine Moore
5 months
The simple life of a Japanese capybara who makes a living from vibe coding apps
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@jandom_random
Jan Domanski
5 months
Sounds familiar indeed
@tunguz
Bojan Tunguz
5 months
This really hits close to home for me. My whole career in tech was one big unsuccessful struggle to try to explain the distinction between these various modes of operation, and why you will fail miserably if you try to impose a single mindset for all of them.
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@jandom_random
Jan Domanski
5 months
Has somebody tried boltz-2 with perturbed “off-pocket” crop? Such that the predicted structure cannot be corrected (eg picked residues are outside the binding pocket) and checked if the affinity head is still working? (It shouldn’t be under such perturbation)
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@jandom_random
Jan Domanski
5 months
GCP on fire 🔥 Some AI intern caught loose? :P https://t.co/GEkdYbJ3KO
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@jandom_random
Jan Domanski
6 months
Memory Lost !!
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@jandom_random
Jan Domanski
7 months
A friend in need is a friend indeed!
@unusual_whales
unusual_whales
7 months
Britain and the European Union are set to sign a formal declaration committing to “free and open trade," per POLITICO
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@jandom_random
Jan Domanski
7 months
Lets goooo
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@jandom_random
Jan Domanski
8 months
Google probably has the best models but still builds crappy products around them
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@jandom_random
Jan Domanski
8 months
This is a flow that 2tn dollar company has for an in-app upgrade (it doesn’t: sends you to a random help article) BTW the browser version lets you use Gemini 2.5 but the app doesn’t
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@jandom_random
Jan Domanski
8 months
Never confuse charisma&confidence for competence.
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@jandom_random
Jan Domanski
8 months
Not quite but thanks! 😹
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@jandom_random
Jan Domanski
8 months
A large fraction of #compchem problems could be settled by just two things - believable (industry?) datasets around a property of interest - a suitably expressive software to run multiple tools quickly on above dataset & evaluate 🌶️🌶️🌶️
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@jandom_random
Jan Domanski
8 months
This is obviously true to anyone working in tech… yet remains a mystery/curiosity to other industries…
@ClementDelangue
clem 🤗
8 months
Great research on open-source by @Harvard: - $4.15B invested in open-source generates $8.8T of value for companies (aka $1 invested in open-source = $2,000 of value created) - Companies would need to spend 3.5 times more on software than they currently do if OSS did not exist I
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@jandom_random
Jan Domanski
8 months
Very pleased to see this work out, and massive thanks to everyone involved! This works shows the incredible potential of combining the new ML tools with existing biophysical methods, including FEP. Also, an example of *actually* using ML in a real drug-discovery program :)
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@WaxBallze
Max Stolze
9 months
This Indian restaurant is named after the great French scientist, Marie Curie❤️⚗️
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@seatsixtyone
The Man in Seat 61
9 months
Interesting. And a Milan-Ljubljana Frecciarossa on the cards from June.
@EuropeanRailTT
European Rail Timetable
9 months
Read our thoughts about Trenitalia's expansion plans https://t.co/qjg0VrBeFs Photo by Florian Pépellin (CC-BY-SA 4.0). Frecciarosa train 9296 from Milano to Paris at Modane.
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@paulg
Paul Graham
10 months
Apparently EU users don't get new AI versions till several months after US users, because AI companies have to get regulatory signoff first. Was the cost of overregulation ever so clear? Every user in Europe is several months behind, in a field that changes every several months.
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@jandom_random
Jan Domanski
10 months
If you care about EU tech you should speak 🆙
@euacchq
eu/acc
10 months
Good morning. Last call. Today is the last day to give your feedback. It can be anonymous and it can be just a few words. Remind the EU Commission you want a company law that is fully digital, notary-free and that we don't want notaries in the future of company law. It is
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