We are no longer accepting applicants for our open-label mechanistic study on Psilocybin for fibromyalgia, thank you for those who applied, watch this space for updates and results. https://t.co/xCjMYF1P8X @juliabornemann @Dr_Kirran @RCarhartHarris @ProfDavidNutt

Hello Denver 👋🏼 #PS2025

'another sin of human hubris at arguably the most famous shrine to the folly of human hubris in history' https://t.co/hqS3fQUsXq

Evolutionary psychiatry @RoySocMed

Yesterday, the U.S. Government Accountability Office (GAO, the constitutional version of DOGE) published a Science & Tech Spotlight on the 'Medical Use of Psychedelics'. According to GAO, over 340 trials on psychedelics were active between 2015 and early 2025.

"One sees whatever he wants, when looking into the uncertainty" - Xavier Bichat's critique of microscopy, which of course in time turned out to be essential to our understanding. The same critique is made of fMRI today.

🫴A sense-ational #ImperialLates all about Senses 👂 👀Catch a free night full of immersive and interactive experiences, talks and more 👃 plus tasty food and a fully stocked bar 👅 📍 @imperialcollge @ImperialSpark 📅 Thu 5 Dec, 6pm - 9pm 🎟️ free 🔗 https://t.co/IXT3eN7sQf

Prohibition does not stop drug use or drug-related deaths. It only increases risk by allowing lucky-dip cocktails like this on the market. #Liam #drugspolicy @guardian @TransformDrugs

This makes me proud, just over 100 years after @EdinburghUni admitted the first women medical trainees, @LindaFoundation and Scotland make history again:

@REMAPTherapy @JacobSAday @boehnkster @juliabornemann @RCarhartHarris @IASPpain @PhysioPainAssoc @laurarathbone @diarmuiddenneny @fmauk @PainResForum @pain_europe

…..there is a small but growing body of evidence looking at autoimmune, genetic, epigenetic contributors to fibromyalgia. Dr Claw’s final slide summed it up nicely for me (9/9):

🗞️In summary, I still don’t fully understand #fibromyalgia, but that’s OK, no-one does. The strongest evidence supports a ‘top-down’ central process, but there are also bottom-up drivers. Psychological factors such as ACEs have an impact, but are unlikely causative....(8/9)

Two FM posters that stood out (7/9)

Andreas Goebel of @LivUni spoke to autoimmune activity in FM. (6/9)

Daniel Clauw of reviewed central sensitisation, as well as evidence contradicting other mechanisms (5/9)

@cl_sommer made the case for fibromyalgia and small fibre neuropathy, bring this into a more integrated model 👇🏼 (4/9)

Winifred Hauser reviewed Fibro from a psychiatric lense. Thankfully we have come a long way in this area, although some work to do on translating research to clinical practice (3/9)

Jacob Ablin explored how genetics and epigenetic factors could predispose people to fibromyalgia (2/9)

🧵Reviewing some of #IASP2024 ‘s content on Fibromyalgia. Notably, the @PAINthejournal Reports Symposium: ‘Fibromyalgia: Who are you?’ (1/9)

Nocebo, the dark side of social context in pain experiences @IASPpain #IASP

Touchdown in Amsterdam for @IASPpain @IASPnetwork #iasp2024 👋🏼