Jake Kelly MD
@jakekellymd
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Performance Cardiologist | VO₂ Max, Metabolic Health & Longevity Strategist | Ironman Triathlete | Father of 3 |
Anchorage, AK
Joined January 2009
✈️ Somewhere between Barcelona and Anchorage, I realized something: “Heart healthy” advice isn’t enough anymore. Here’s what actually matters — and how to build it. 🧵
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VO₂ max isn’t built in perfect conditions. It’s built by consistency across seasons, stress, and schedules.
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Most cardiometabolic disease isn’t about what people do. It’s about when. Sleep timing, morning light, early movement & regular meals. Circadian rhythm is preventive medicine hiding in plain sight.
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Strength is a longevity drug. Not for size or hypertrophy. For function. Carry. Push. Pull. Hinge. 2–3 short sessions a week will change your future.
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Cardiologists talk about cholesterol, stents, and medications. But the strongest predictor of how long you’ll live and how well you’ll function is VO₂ max. Not genetics. Not age. Not LDL. VO₂ max is trainable at every decade of life.
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Most 80-year-olds can’t walk up a hill without stopping. My 80-year-old mom is in the top ~1–2% VO₂ max for her age. No lifelong athletics. No supplements. Just consistency, walking, and light strength. Cardiovascular fitness doesn’t fade with age; it fades with inactivity.
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Thanks for the shoutout from @Alan_Couzens. A special write-up and a telling story on a life well-lived.
A must-read from @jakekellymd ... "What an 80-year-old can teach us about VO2max and longevity" 🙌 https://t.co/MRH4wMvzHn
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A must-read from @jakekellymd ... "What an 80-year-old can teach us about VO2max and longevity" 🙌 https://t.co/MRH4wMvzHn
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Kids don’t care about “exercise.” They care about adventure. Best longevity habit for winter: 20 minutes outside. Walk. Sled. Breathe. Play.
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Winter raises BP. Walking lowers it. Sleep and strength do the rest.
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GLP-1s are amazing tools. BUT, you must "repair" upstream dysfunction, ideally at the same time to prevent relapse @neuroteg @JAMAInternalMed @yaleHFdoc
@JAMAInternalMed “Downstream GLP-1 drugs lead to relapse when stopped because the upstream biology was never repaired. Upstream GLP-1 strategies (metabolic, immune, liver, vascular, microbiome, neurocircuit repair) aim for durability, not dependency. GLP-X measures that shift.”#GLP1
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Up early again. Mind loud. Heart steady. Cool water. Hot coffee. Write until the static dissolves. Stress out. Clarity in. Sometimes you have to let it all out To let more in.
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If you’ve ever had a health scare that logic couldn’t quiet… my story may help. 👇 Full article https://t.co/cMfVvjJWmZ
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As a cardiologist, I see this weekly. And this time, I became the patient. It changed the way I practice. It made me more empathetic. More human.
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ER tests can be normal: ECG, troponin, chest X-ray. But the fear remains. Why? Because anxiety is a physiologic event, not “just worry.”
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The scary part? Anxiety often presents as real physical symptoms: • chest tightness • racing heart • shortness of breath • dizziness • abdominal pain • a sense of doom
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The fear wasn’t logical. It didn’t match the data. But it took over my physiology anyway. (If you’ve ever had chest pain, palpitations, or a sudden health fear… you know exactly what I mean.)
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Not physically. Not medically. But mentally. Anxiety didn’t whisper. It detonated.
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I’ve been physician and cardiologist for 20+ years. I stay calm in every crisis. But one morning in Hawai‘i, a small dog bit my leg… and I completely fell apart.
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