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Inherited Cancer Registry (ICARE) Profile
Inherited Cancer Registry (ICARE)

@inheritedcancer

Followers
461
Following
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Media
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"To end the cycle of inherited cancer through research, education, and engagement" The information provided on our page is not a substitute for medical advice.

Nashville, TN 37212
Joined August 2019
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@inheritedcancer
Inherited Cancer Registry (ICARE)
4 months
#TNBC is more common among Black populations from Africa, the Caribbean, & US. Emerging data suggests it may also be more common in other non-European populations, highlighting the importance of studying ALL populations so everyone has the chance to benefit from #genomic advances
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@inheritedcancer
Inherited Cancer Registry (ICARE)
4 months
Different #breastcancer genes🧬lead to different levels of #risk: High risk genes (more than 4-fold risk) include #BRCA1, #BRCA2, #PALB2, #TP53, #PTEN, #CDH1 Less high risk genes (2-4 fold risk) include #CHEK2, #ATM, #BARD1, #RAD51C, #RAD51D #InheritedCancer #Genetics #Education
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@inheritedcancer
Inherited Cancer Registry (ICARE)
4 months
1 in 10 people with #osteosarcoma have an #inheritedcancer risk gene mutation. If you are a #sarcoma patient, you may want to consider #genetictesting and joining our #CAUSAL study, which involves free inherited cancer genetic testing & tumor testing: https://t.co/sg8jjc4DON
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@inheritedcancer
Inherited Cancer Registry (ICARE)
5 months
Genetic testing for #inheritedcancer can help guide #care, including: • #treatment plans, such as chemotherapy, drugs, surgery, and radiation • #screening and #prevention Sharing genetic test results can also help family members understand their #cancerrisks.
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@inheritedcancer
Inherited Cancer Registry (ICARE)
5 months
.@NCCN released updated Genetic/Familial High-Risk Assessment: #Colorectal, #Endometrial, #Gastric #Cancer guidelines on June 13th, including updates to clinical diagnostic criteria for #PeutzJeghersSyndrome among many other important updates. Read more at https://t.co/ZfKZCYP9P0
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@inheritedcancer
Inherited Cancer Registry (ICARE)
5 months
Have you already had genetic testing for inherited cancer and would you like to contribute to inherited cancer research? Enroll in ICARE today at ⤸ https://t.co/N3nUD73EuP #InheritedCancerRegistry #InheritedCancer #HereditaryCancer #Cancer #CancerResearch #CancerAwareness
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@inheritedcancer
Inherited Cancer Registry (ICARE)
5 months
Do you have a history of #breastcancer and an #ATM mutation? Join #ICARE at https://t.co/N3nUD73EuP to contribute to #tumor #genomics studies to better understand breast cancer in ATM carriers. With your help, we hope one day our research may lead to new or refined #treatments!
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@inheritedcancer
Inherited Cancer Registry (ICARE)
5 months
July 13th is #GastrointestinalStromalTumor (GIST) #Awareness Day! Inherited conditions that can lead to GISTs include primary familial #GIST syndrome, #neurofibromatosis type 1 (von Recklinghausen disease), and #CarneyStratakis syndrome. Learn more at 👇 https://t.co/RExAco5lfD
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@inheritedcancer
Inherited Cancer Registry (ICARE)
5 months
At the @NCCN 2025 Annual Conference, several experts in the field of #inheritedcancer discussed genes related to prostate, endometrial, & gastric cancers and updates to the #NCCN #Guidelines for Genetic/Familial High-Risk Assessment. Learn more at: https://t.co/a4zmqa2RS5
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@inheritedcancer
Inherited Cancer Registry (ICARE)
5 months
Watch an excerpt from yesterday's #ICARE #Genetics Case Conference during which Elizabeth Swisher, MD from the University of Washington (@UW) discusses Myelodysplastic Syndrome (#MDS) and Acute Myeloid #Leukemia (#AML) following #PARPinhibitor therapy ⤸ https://t.co/x7BhkFuEdl
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@inheritedcancer
Inherited Cancer Registry (ICARE)
5 months
.@NCCN just released updated Genetic/Familial High-Risk Assessment: #Breast, #Ovarian, #Pancreatic, & #Prostate #Cancer guidelines today! These new guidelines include updates to #CHEK2, #PALB2, #TP53, & #PTEN content and much more! Check them out at: https://t.co/bs0a9rnDB9
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@inheritedcancer
Inherited Cancer Registry (ICARE)
5 months
#BRCA1 & #BRCA2 are among the most well-studied genes, yet most BRCA studies have been done in White populations. This means our knowledge about genes & risks comes mainly from White populations. #Diversity in #genomicsresearch is vital to prevent further widening of #disparities
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@inheritedcancer
Inherited Cancer Registry (ICARE)
5 months
Watch an exciting presentation from the @NCCN 2025 Annual Conference to learn about genes related to #prostate, #endometrial, & #gastric #cancers as well as the expanded recommendations in the #NCCN Guidelines for Genetic/Familial High-Risk Assessment ⤵ https://t.co/f4z4gWDwES
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@inheritedcancer
Inherited Cancer Registry (ICARE)
5 months
If you have a history of #breastcancer and a #mutation in #BRCA, #PALB2, #ATM, or #CHEK2, you may be eligible to contribute to tumor #genomics studies that are being conducted through the #ICARE. To learn more about participating or to enroll online, visit https://t.co/N3nUD73EuP
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@inheritedcancer
Inherited Cancer Registry (ICARE)
5 months
A trial among #BRCA carriers comparing neoadjuvant #chemo with #olaparib vs. chemo alone found no improvement in pathologic response (64.1% vs. 69.8%) yet significant improvement in overall survival at 3 yrs (100% vs. 88.2%). Read the full article at: https://t.co/ry8k3hSpEr
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@inheritedcancer
Inherited Cancer Registry (ICARE)
5 months
Did you know ~80% of #genomics data comes from Europeans, yet they only make up ~16% of the world population? This #bias means important associations for other #ancestry groups may be missed. Not including #diverse populations in genomics #research can further WIDEN #disparities!
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@inheritedcancer
Inherited Cancer Registry (ICARE)
5 months
Check out our YouTube channel to listen to experts discuss #inheritedcancer-related topics, including updates to NCCN #guidelines and the latest information on certain inherited cancer #genes. https://t.co/QGu41EwMmS #cancer #genetictesting #cancergenetics #gcchat
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@inheritedcancer
Inherited Cancer Registry (ICARE)
5 months
July is #Sarcoma and #BoneCancer #Awareness Month! Inherited #genes that lead to higher risks of these tumors include: #TP53, #RB1, #NF1, #APC, #KIT & #PDGFR. To learn more, read the following article 👇 https://t.co/86pdgy4YWx
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@inheritedcancer
Inherited Cancer Registry (ICARE)
5 months
A new study found that compared to those with #BRCA2 variants outside exon 11, those with exon 11 mutations had lower #breastcancer risk, higher risk for ER-negative disease, and later age at diagnosis. Learn more at: https://t.co/88kD218sQg
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@inheritedcancer
Inherited Cancer Registry (ICARE)
5 months
#TNBC is more common among Black populations from Africa, the Caribbean, & US. Emerging data suggests it may also be more common in other non-European populations, highlighting the importance of studying ALL populations so everyone has the chance to benefit from #genomic advances
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