Explore tweets tagged as #AMPtutorials
In NGS, variant allele fraction (VAF) correlates with how many DNA strands had the mutation in the original sample. We try to correlate it with tumor cellularity and possible germline status, but a lot can change it (1/11) #amptutorials #pathtwitter #medtwitter #pathologists
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Homologous recombination deficiency (HRD) and PARP inhibitors are kind of a confusing topic. HRD is caused by defects in the homologous recombination repair (HRR) proteins, which repair double-strand breaks by using the homologous chromosome as a template. #AMPtutorials (1/10)
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For children with Wilms tumor, each of these are associated with aggressive disease:.•1p and 16q LOH.•1q gain.•TP53 mutation or deletion.•MYCN amp. Molecular is now indicated for all favorable histology Wilms. Learn more in our shortcourse #USCAP2024. #AMPTutorials #pedipath
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Me not panicking about #pathology boards 😁📚 . Here's a 🧵 I compiled on some cancers and their associated mutations 🧬. Hope you find it useful 🙌🏽. #PathX #PathTwitter #MolPath #MedTwitter #AMPtutorials ✨
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Honored to join the AMP Social Media Challenge Working Group under the leadership of Dr. @AlannaChurch_MD !. Over the next 2 years, I’ll be part of the team judging submissions for #AMPtutorials and contributing to program improvements. Grateful to @AMPath for this opportunity!
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PIK3CA tweetorial (🧵 1/6). The PIK3CA gene encodes the p110-alpha catalytic subunit of PIK3 pathway; pathogenic/ oncogenic variants often result in overactivation of this pathway (gain-of-function). #AMPtutorials #Molpath #path2path #PathX
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Share your molecular knowledge with our #AMPtutorials challenge! Post your social media tutorial on any molecular topic on your platform of choice. Winners will get free registration to the #AMPath24 meeting. More info here: #molpath
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In this #AMPtutorials, we will discuss the role of the TMPRSS2::ERG fusion in prostate cancer (PCa), and its therapeutic implications. What do you know about the fusion? 🧬. #Molpath #GUpath #ProstateCancer .@AMPath @MGBpathology @MGHPathology
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Stay informed about EWSR1-rearranged sarcomas for accurate diagnosis & management! . #MolecularPathology #BSTpath #AMPtutorials
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PIK3CA tweetorial . The majority of hotspot variants in the gene PIK3CA are in the helical and kinase domains. #AMPtutorials
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PIK3CA tweetorial . The PIK3CA variants can be associated with malignancies and PIK3CA-Related Overgrowth Syndrome (PROS). #AMPtutorials
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PIK3CA tweetorial. Many clinical laboratories now utilize targeted next-generation sequencing (NGS) assays for PIK3CA testing. #AMPtutorials
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PIK3CA tweetorial. Alpelisib and capivasertib, when combined with the selective estrogen degraded, fulvestrant, as well as inavolisib inhibitor combination with both fulvestrant and palbociclib are FDA approved/ NCCN recommended therapies . #AMPtutorials
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Thank you Dr. @AlannaChurch_MD and @AMPath for this award! Always grateful to my @templepathology family and the Twitter family for teaching and encouraging me to ask and think about the ‘Why’ and ‘How’ questions more. 🧬✨.#AMPath #AMPath24 #Hemepath #Molpath #AMPtutorials
Congratulations @whosainastro, our second winner of the @AMPath #AMPtutorials social media challenge the fascinating history of p53 🧬. He's won free registration to the #AMP24 meeting in Vancouver 🇨🇦.
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Common method for detecting ALK gene fusion in the routine molecular pathology laboratory.#MolecularPathology #BSTpath #AMPtutorials
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Our 2025 Social Media Challenge is accepting entries! To participate, post a short #molpath tutorial on your favorite social platform and send us the URL. View details: #AMPtutorials
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Share your molecular knowledge with our #AMPtutorials challenge! Post your social media tutorial on any molecular topic on your platform of choice. Winners will get free registration to the #AMP2024 meeting. More info here: #pathtwitter #molpath
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Do you have a entry for our 2025 Social Media Challenge (#AMPtutorials)?. Post a short tutorial on any #molpath topic on the social media platform of your choice. Enter to win a free pass to #AMPath2025. Details and entry form:
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Honored to be announced as one of the winners of the AMP Social Media Challenge during the AMP Business and Awards Ceremony 🧬✨#AMP2024 #AMPtutorials
Why is p53 called p53? 🤔. A 🧵 about the history and discovery of the most studied gene in human history, also known as the guardian of the genome. 🧬 #pathtwitter #pathX #molecular #history.
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