Hamieh Mohamad
@hamieh
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Assistant Professor @WCM , @WCMpeds, @WCM_MeyerCancer, @parkerici, #Immunology, #Immunotherapy, #CART
New York, NY
Joined October 2008
Our new paper describing a novel synthetic co-stimulatory molecule designed to boost anti-tumor responses is out in @NatureCancer .
nature.com
Nature Cancer - Dobrin et al. develop a fusion receptor comprising the CD80 ectodomain and the 4-1BB cytoplasmic domain, which engages the CD28 and 4-1BB pathways and increases the antitumor...
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RT @NatureCancer: ✨ONLINE NOW @NatureCancer “Synthetic dual co-stimulation increases the potency of HIT and TCR-targeted cell therapies” #C….
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RT @ElizSMcKenna: In the April issue of @CD_AACR - a new review by @hamieh @JorgeMansilla_S Isabelle Rivière & @Michel_Sadelain @MSKCancerC….
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RT @sloan_kettering: 🚨 Our Dr. Michel Sadelain will deliver the George Stamatoyannopoulos Memorial Lecture tomorrow at #ASGCT19. The lectur….
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RT @deguine_j: The new smart cars at #AACR19 : Sadelain, Lim highlight current thinking of improving CAR-T #immunotherapy, by targeting wit….
nature.com
Nature - Chimeric antigen receptors (CARs) promote antigen loss in tumour cells by trogocytosis, which results in T cell fratricide killing and exhaustion but can be counteracted by cooperative...
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RT @Immune_News: CAR T cell trogocytosis and cooperative killing regulate tumour antigen escape @sloan_kettering.
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RT @SciImmunology: ICYMI, @sloan_kettering scientists have identified new structures that play a critical role in one of the most protectiv….
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RT @charles_ferte: What is the difference between 28z and BBz CAR-T ? Toxicity , persistence, effector function . Beautiful talk by Michel….
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RT @enhancerleo: Don't bite off more than you can chew! CD19 #CARTcells acquire CD19 from #cancer cells by #trogocytosis, helping #tumor #e….
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Brilliant. .
On the Nature cover this week: Under pressure. How the immune system shapes cancer evolution. Browse the contents page for this issue:
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RT @notSoJunkDNA: Who needs Game of Thrones when you can summarize a paper by "(CARs) promote antigen loss in tumour cells by trogocytosis,….
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RT @anton_gh: Mind blowing paper by Sadalain lab: trogocytosis and cooperative killing regulate tumour antigen escape. What an interesting….
nature.com
Nature - Chimeric antigen receptors (CARs) promote antigen loss in tumour cells by trogocytosis, which results in T cell fratricide killing and exhaustion but can be counteracted by cooperative...
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RT @mvicaracal: Online @nature: CAR T cell trogocytosis and cooperative killing regulate tumour antigen escape
nature.com
Nature - Chimeric antigen receptors (CARs) promote antigen loss in tumour cells by trogocytosis, which results in T cell fratricide killing and exhaustion but can be counteracted by cooperative...
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RT @pcandersson: Loss of antigens, and T cell dysfunction are hurdles for successful #CARTcell therapies. A new study published by authors….
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RT @NYTHealth: A daring cancer therapy that few doctors believed would work has sent some cancer patients into complete remission. https://….
nytimes.com
After a long, intense pursuit, researchers are close to bringing to market a daring new treatment: cell therapy that turbocharges the immune system to fight cancer.
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RT @sloan_kettering: MSK researchers made some groundbreaking discoveries in 2015. Check out 3 highlights: https://….
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RT @NatureBiotech: Optimizing costimulation boost efficacy of CAR T Cell therapy in mice http://t.co/1cel2hZ0Dn
#NBThighlight.
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