Gabe Stine
@gabrielmstine
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Postdoctoral associate at MIT studying the neuroscience of cognition and learning. Previously in the Shadlen lab at Columbia.
Joined March 2017
I’m thrilled to share two preprints in which we use new NHP neuropixels probes to shed light on the neural mechanisms of decision formation and termination. The probes allowed us to record simultaneously from 100s of neurons in LIP in a single session 1/N.
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RT @RaynorProject: Thank you to all our incredible attendees for your engagement and openness throughout the week. We hope you enjoyed the….
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RT @CMZiemba: The long gestating final chapter of my thesis is out in.@SfNJournals this week as a featured cover article. Thanks to all….
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RT @gabrielmstine: Proud that the last of my PhD work is finally out, with co-first author @NatSteinemann. And check out the great insight….
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These methods suggest that the DV is an emergent signal of the population (distributed coding). In other words, leveraging the known functional organization of single neurons led us to fundamentally different conclusions about neural coding in LIP. Check out the paper for more!.
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Second, neurons with the appropriate response field directly signal the decision variable. A simple average of a handful of these neurons (0 DoF) renders signals that are almost identical to those rendered from dim. reduction methods that use the full population (100s of DoF).
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First, fits of a DDM to the behavior render quantitative predictions for what we ought to observe in the neural dynamics and their relationship to choice/RT. The agreement between these predictions and the data is, IMO, remarkable. This is more than a vague, qualitative match.
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Proud that the last of my PhD work is finally out, with co-first author @NatSteinemann. And check out the great insight article from Bharath Talluri and @nienborglab: Below I highlight two findings of the paper that I think are particularly noteworthy.
Finally! This is the version of record; it's also the version to read, thanks to the review process at eLife. The finding was out of reach before macaque Neuropixels. @eLife: Direct observation of the neural computations underlying a single decision
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RT @gabrielmstine: I'll also be an "expert" at the neuropixels booth on Sunday afternoon from 2:30–3:30pm to offer advice on using neuropix….
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I'll also be an "expert" at the neuropixels booth on Sunday afternoon from 2:30–3:30pm to offer advice on using neuropixels-nhp probes. Stop by and say hello!.
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Excited to be presenting my ongoing postdoctoral work at #sfn2024! Come visit my poster on Saturday afternoon and learn about how the cerebellum interacts with thalamus and neocortex to support non-motor error-correction and adaptation.
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There's a box missing:. Does it go away after spinning around three times and lifting your pencil? ----> The ephys gods were unhappy.
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RT @stevewcchang: We are sharing this important commentary with the research community as a Commentary piece just published in the Journal….
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RT @MIcheleABasso1: Hello all! Please give this a read - and amplify! #SimCo2024 #ThankAMonkey #EndSufferingThruScience..
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RT @ThomElston: 🚨 I am looking for a postdoc! We'll get into multi-site neuropixel recordings and closed-loop stimulation in NHPs performin….
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Couldn't agree more. So frustrating that we don't have more mechanisms for retaining our most experienced, knowledgeable, and skilled scientists. Just seems stupid strategically.
Another insightful, forward-thinking article from The Transmitter. I'll go even further. As someone with experience in both academia and industry, I think that academia's inability to create meaningful careers beyond principal investigator roles is significantly holding it back.
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Inspiring!.
Our new study is out today in the New England Journal of Medicine! We demonstrate a speech neuroprosthesis that decodes the attempted speech of a man with ALS into text with 97.5% accuracy, enabling him to communicate with his family, friends, and colleagues in his own home. 1/9
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RT @chris_fetsch: Happy to share a new preprint by the brilliant and indefatigable @MiguelVivarLazo. The first of several stories we want t….
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This fact played a big role in my recovery from cortical chauvinism. Those ignoring the cerebellum are missing a big piece of the puzzle.
From an evolutionary perspective, what distinguishes the human brain?.You may say, the neocortex. Surprisingly, in humans and other great apes, the expansion of the cerebellum accelerated faster than the enlargement of the cerebral cortex.
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RT @shadlen: Thanks to highly competent reviewers, this is a more rigorous improved version. I hope colleagues consider the counterfactual….
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