@InamoriNews 【訂正】本研究は広瀬さん(元特定准教授)の稲盛財団研究助成2023採択課題の成果です。.

We share another new research. A membrane lytic peptide-modified polysaccharide was developed in this paper. It forms a stable coacervate and efficiently delivers IgG into cytosol. This work has been selected as a cover in Bioconjug. Chem. #L17E #IgG

本研究は広瀬の稲森財団研究助成2023採択課題の成果です。@InamoriNews.

commentary→

@MolTherapy

Our new work has been published in @MolTherapy. This paper demonstrates a novel mechanism of cytosolic delivery mediated by the L17E peptide and highlights the important role of the calcium-activated potassium channel KCa3.1 in supporting this delivery process.

By modulating RNA-binding affinity, novel m6A erasers (modFTO & modALKBH5) were created that minimize off-target effects with programmable RNA-binding proteins and enable ligand-responsive control. This work has been selected as a cover in Chem. Commun.

We're thrilled to share our new research about an innovative approach for precise and time-controllable m6A RNA demethylation. #m6A #Epitranscriptomics #RNA #ChemCommun

Our new review article highlights the design of intracellular delivery peptides and new delivery methods, such as coacervate, for intracellular protein delivery. #protein #delivery #peptide.

We are delighted to share our latest paper titled "ATP2B4 is an essential gene for epidermal growth factor-induced macropinocytosis in A431 cells." This research sheds light on #ATP2B4 as a pivotal gene related to #macropinocytosis induction.

日本薬学会第144年会（@パシフィコ横浜）でシンポジウムを開催します.[S58]「RNA疾患のメカニズムと創薬に向けたRNA操作」.3月31日(日) 09:45 〜 11:45　会議センター 502 (5F).薬学会にご参加のみなさま、ぜひお越しください！.

We are happy to share with you that our paper entitled "E3MPH16: An efficient endosomolytic peptide for intracellular protein delivery" is now published online @JCRnEDITORS

Our paper entitled "Liquid Droplet-Mediated Formulation of Lipid Nanoparticles Encapsulating Immunoglobulin G for Cytosolic Delivery" has been published online in @Mol_Pharm.

RT @hirohide_saito: AIにより機能性RNAを生成できる新技術「RfamGen」を@naturemethodsに本日発表しました！.RNA配列と2次構造を学習することで、目的の機能をもつRNAを効率よく生成できるAI, RfamGenを開発しました。大学院生の….

RT @hirohide_saito: 本日尊敬する先生とお話する機会があり、心に留めたいことをメモします。.1. 基礎を徹底的に勉強する。.2. 一見当たり前と思われることも実際に手を動かし検証して、さらに技術と知識を高める。.3. 自慢話ではない魅力的な授業を準備して、学生….

RT @icr_ku: Futaki group has published a new article @ACS_AMI !."Inkjet-Based Intracellular Delivery System that Effectively Utilizes Cell….

Our new paper and collaborative work with @MotonariU, entitled "Xanthine derivatives inhibit FTO in an l-ascorbic acid-dependent manner", has been published in Chemical Communications.