Fabiola Valdivia Francia
@fabivf90
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PhD Student at @uzh_irem
Zurich, Switzerland
Joined February 2012
Excited to share our lab’s latest preprint: In vivo single-cell CRISPR screening for microproteins identifies a critical ribosomal component. Check out how we systematically explore #microprotein functions and how they expand the cellular proteome!
Our genome encodes > 7000 microproteins that have been previously ignored in genome annotations. How do these microproteins impact tissue function? Here, we use an in vivo single-cell CRISPR screen to systematically explore microprotein function. 1/9 https://t.co/qGeefkiqVH
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Check out our lab’s most recent pre-print: “In vivo single-cell ribosome profiling reveals cell-type-specific translational programs during aging” featuring @clarasdure work!
How does aging alter the translational landscape of stem cells and how do these changes impact their regenerative capacity? Here we developed an in vivo single-cell ribosome profiling strategy to monitor translational landscapes of the mouse skin. 1/6 https://t.co/0QUQQx6UJI
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Had an amazing time at the #ncRNA2024 meeting! It was exciting to share and discuss our work. Huge thanks to the organizers for this incredible opportunity!
Big congratulations to Fabi (@fabivf90) for winning the best oral presentation award at the ncRNA World Conference! Stay tuned for her upcoming preprint on her exciting single-cell CRISPR screen revealing novel microproteins in cancer.
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Check out our lab’s latest work, just published in @Nature! Huge shoutout to @PeterFRenz3 for his incredible work! Happy to finally see it published! It’s been truly inspiring to be a small part of this journey and the Sendoel Lab!
Clonal expansions can remodel entire tissues even when they appear normal, but what mechanisms drive this? And how do these processes differ from tumorigenesis? Out @Nature, we identify distinct TNF programs during tumor evolution. 🧵 https://t.co/S3w9Zl1NE2
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Happy to share our latest review about the dark proteome and microproteins encoded by small open reading frames (#sORFs). Here we describe the tools used to detect and study #microproteins! https://t.co/xO3dT19TSv
The dark proteome encoded by more than 7200 annotated sORFs is redefining our understanding of the human genome. Interested in how to detect microproteins? Check out Fabiola's recent review "No country for old methods". https://t.co/ac0yZ64XSC
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Thank you to the #BarcelonaBioMed conference organizers for giving me the opportunity to present my PhD work during the #CancerinContext meeting! It was inspiring and exciting to meet everyone and exchange ideas during the conference! @IRBBarcelona
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Check out our lab’s most recent pre-print! Amazing science by @PeterFRenz3 ☺️
Happy to share the latest pre-print from our lab. A single-cell CRISPR based investigation into clonal expansion and early tumorigenesis. https://t.co/yjKsn7o6FX A great team effort with @moorlab and @s__ellis
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https://t.co/diUAVIV9BU New review in @ELS_CellBiology together with @fabivf90 from the SendoelLab @uzh_irem is out. Learn all about the regulation and function of 5'UTR small ORFs. #smallORFsbigimpact #somelikeittranslated
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