Ethan Perlstein bio/acc
@eperlste
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ceo @PerlaraPBC (@ycombinator W16), ceo @epalrestat, ceo @endrarediseases, solo vc @AngelList, evo pharmacologist, mTOR worshipper, cofounder of K&L
Bicoastal
Joined January 2011
PMM2-CDG pioneer Maggie has been on epalrestat for almost two years as part of an ongoing single-patient IND study. Her first dose was January 2020. See the results with your own eyes 👇
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RT @ihteshamit: This one paper might kill the LLM agent hype. NVIDIA just published a blueprint for agentic AI powered by Small Language M….
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RT @VerbinnenAndrew: under appreciate fact about launching a telehealth like is that it allows us to collect clinic….
anagen.xyz
Get personalized hair loss treatments developed by leading scientists at competitive prices.
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RT @noor_siddiqui_: Preventing suffering in the future doesn’t diminish the dignity of people living with conditions today. That’s a false….
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We scientists need to start calling ourselves “data artists” since we paint pictures with data.
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Same goes for scientists: you will be outcompeted by your peers at your peril. AGI is kinda here for those who know how to prompt for it.
Almost every study shows doctors with AI perform better than those without. Now AI is achieving perfect scores in medical licensing exams. You will simply expect every professional services provider you go to will use AI in the future or you won’t trust the advice.
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Every scientist should be doing this already.
I’m excited to share the first part of an absolutely stunning analysis from the GPT-5 thinking model! I uploaded a huge spreadsheet, nearly 1,300 metabolites (lipids, carbohydrates, microbiome-derived compounds, and much more) measured in 150 ME/CFS patients and 100 healthy
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GPT-5 will soon be bragging about how fast it finishes — down to the millisecond. My AI dudes: please don’t apply this algorithm to your dating life.
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I think we’ve just achieved AGSI: . Artificial Grad Student Intelligence.
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The frontier models are jagged but so is human intelligence.
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VCs and Wall Street already get to speculate on treatment and cures. Why not let degens join the biotech capital formation party?.
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The road to longevity is paved with rare disease treatments and cures.
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RT @pumpdotscience: you either die a degen. or live long enough to become a PhDegen. let's relive the drama ⤵️
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Crowdfunding ➡️ Internet capital markets. Online communities ➡️ Token networks. TradBio ➡️ DeSci.
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Compounds that can be repurposed for inherited metabolic diseases might also extend lifespan in wildtype model organisms, starting with worms. Now that would be a rare-to-common therapeutic goldmine!. @mkaeberlein @agingdoc1.
worm experiments now live - join us in the lab
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TradBio is still sleeping on internet capital markets but the PhDegens are wide awake.
now live . meet us in the lab.
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