eperlste Profile Banner
Ethan Perlstein bio/acc Profile
Ethan Perlstein bio/acc

@eperlste

Followers
19K
Following
94K
Media
1K
Statuses
61K

ceo @PerlaraPBC (@ycombinator W16), ceo @epalrestat, ceo @endrarediseases, solo vc @AngelList, evo pharmacologist, mTOR worshipper, cofounder of K&L

Bicoastal
Joined January 2011
Don't wanna be here? Send us removal request.
@eperlste
Ethan Perlstein bio/acc
4 years
PMM2-CDG pioneer Maggie has been on epalrestat for almost two years as part of an ongoing single-patient IND study. Her first dose was January 2020. See the results with your own eyes šŸ‘‡
14
25
250
@eperlste
Ethan Perlstein bio/acc
1 hour
RT @jchervinsky: The GENIUS Act passes the House by a huge margin, 307 - 122. The President will sign it into law tomorrow. We have stable….
0
106
0
@eperlste
Ethan Perlstein bio/acc
1 hour
RT @gdb: ChatGPT Agent: our first AI with access to a text browser, a visual browser, and a terminal. Rolling out in ChatGPT Pro, Plus, an….
0
64
0
@eperlste
Ethan Perlstein bio/acc
2 hours
The value prop of DeSci for Pharma is making the US competitive with China on clinical trial speed and cost. Prove to TradBio that onchain decentralized trials run vastly cheaper and faster, then they’ll be all over crypto. .
0
0
0
@eperlste
Ethan Perlstein bio/acc
1 day
yah but yeast is still the hottest model organism.
@NIH
NIH
1 day
A tiny worm called C. elegans is a favorite among biologists. Studies of these wiggly worms have given surprising insights into human health and led to four Nobel Prizes. Learn more:
Tweet media one
0
0
4
@eperlste
Ethan Perlstein bio/acc
2 days
I would hope that the scientists attending a psychedelics conference are on the substances they study in the lab.
2
0
8
@eperlste
Ethan Perlstein bio/acc
4 days
Pitting o3 vs Grok 4 against each other with identical prompts relating to biology specifically. So far not discerning much of a difference. Both are giving similar answers. Feels kinda like talking to a pair of identical twins who were separated at birth.
1
0
5
@eperlste
Ethan Perlstein bio/acc
6 days
How are the 10,000+ rare diseases affecting 1 in 10 Americans NOT a national priority?.
@PRVWatch
PRV Watch
6 days
Marty Makary FDA Commissioner discusses the Commissioner's National Priority Voucher Program on CNBC: What qualifies as a national priority?.šŸ”¹Large unmet public health need. Would like to see:.- cure for T1 diabetes .- more cancer therapies for stage 4 metastatic disease .-.
0
3
6
@eperlste
Ethan Perlstein bio/acc
6 days
RT @eperlste: The biggest regret I have from my all-too-brief stint as CSO of @ReeveFoundation that was cut short by COVID was not being ab….
0
1
0
@eperlste
Ethan Perlstein bio/acc
7 days
The biggest regret I have from my all-too-brief stint as CSO of @ReeveFoundation that was cut short by COVID was not being able to close a partnership with @neuralink. @maxhodak_,whom I knew from YC, was there at the time and we had just one promising intro meeting in late.
@MarioNawfal
Mario Nawfal
7 days
🚨NEURALINK IMPLANTS 7TH PATIENT, MEET JAKE SCHNEIDER. Jake becomes seventh brain chip recipient targeting neurodegenerative diseases. Vows to "redefine what is possible" as Neuralink expands beyond paralysis patients. Source: @PairedWith_P7 @neuralink
0
1
9
@eperlste
Ethan Perlstein bio/acc
7 days
The biggest regret I have from my all-too-brief stint as CSO of @ReeveFoundation that was cut short by COVID was not being able to close a partnership with @neuralink. @maxhodak_,whom I knew from YC, was there at the time and we had just one promising intro meeting in late.
@MarioNawfal
Mario Nawfal
7 days
🚨NEURALINK IMPLANTS 7TH PATIENT, MEET JAKE SCHNEIDER. Jake becomes seventh brain chip recipient targeting neurodegenerative diseases. Vows to "redefine what is possible" as Neuralink expands beyond paralysis patients. Source: @PairedWith_P7 @neuralink
0
0
4
@eperlste
Ethan Perlstein bio/acc
7 days
TradBio is wringing its hands over China eating its lunch, but completely asleep at the wheel on AI which will drive incalculable innovation from below.
1
0
6
@eperlste
Ethan Perlstein bio/acc
7 days
Nothing stops this train.
@balajis
Balaji
7 days
Bitcoin is hitting all time highs.
Tweet media one
1
0
2
@eperlste
Ethan Perlstein bio/acc
7 days
RT @endrarediseases: Curetopia Lab Meeting livestream will be on Monday July 14 @ 9AM PACIFIC . We’ve been heads down cooking and we have t….
0
4
0
@eperlste
Ethan Perlstein bio/acc
9 days
Why stop at a kidney?. Blood, sperm, and ovaries are fungible too!.
0
0
7
@eperlste
Ethan Perlstein bio/acc
9 days
If the frontier models today can save 10 hours for every one of the 50M+ PhD scientist on Earth, that equates to a collective productivity unlock of 1000 millennia!. We have no idea what’s coming, but it’s the biggest thing since sliced bread.
@DeryaTR_
Derya Unutmaz, MD
9 days
This graphic doesn’t even represent the advanced AI models. What OpenAI or Google DeepResearch models can complete in 15-20 minutes would take me dozens of hours. I’m also testing a model that’s even much further ahead…what’s coming is a far bigger hurricane! I’ll keep warningā˜ŗļø.
1
1
13
@eperlste
Ethan Perlstein bio/acc
9 days
This FDA is the most community engaged I’ve ever seen — take them up on their offer!.
@US_FDA
U.S. FDA
9 days
Got a question for the FDA Commissioner?. In our next FDA Direct conversation, we'll be fielding questions from the audience. Click the link below to submit yours!.
Tweet media one
0
1
8
@eperlste
Ethan Perlstein bio/acc
10 days
RT @ElliotHershberg: This is one of the core questions I tried to answer in my recent essay on virtual cells. If we are still far from mod….
0
4
0
@eperlste
Ethan Perlstein bio/acc
11 days
If anyone wants a training set on drug responses in yeast, you know where to find me.
0
0
3
@eperlste
Ethan Perlstein bio/acc
11 days
Love all the talk about virtual (human) cells. But I’ve yet to see any model accurately predict drug response in a simple yeast cell let alone in a complex differentiated human cell. Show me you can accurately predict perturbations in a yeast cell, then I’ll take notice. I.
4
0
44
@eperlste
Ethan Perlstein bio/acc
11 days
Weekends are for vibe CEOing.
0
0
4